Kif3a deficiency reverses the skeletal abnormalities in Pkd1 deficient mice by restoring the balance between osteogenesis and adipogenesis (Q28476413)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151991 AND SRC:MED&resulttype=core&format=json

18 January 2020

title

Kif3a deficiency reverses the skeletal abnormalities in Pkd1 deficient mice by restoring the balance between osteogenesis and adipogenesis (English)

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18 January 2020

1 reference

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151991 AND SRC:MED&resulttype=core&format=json

18 January 2020

Zhousheng Xiao

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151991 AND SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Ni Qiu

1

1 reference

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18 January 2020

Li Cao

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151991 AND SRC:MED&resulttype=core&format=json

18 January 2020

Valentin David

3

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18 January 2020

language of work or name

English

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publication date

2 December 2010

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151991 AND SRC:MED&resulttype=core&format=json

18 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151991 AND SRC:MED&resulttype=core&format=json

18 January 2020

volume

5

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18 January 2020

issue

12

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18 January 2020

page(s)

e15240

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Creative Commons Attribution 4.0 International

18 January 2020

copyright license

start time

2 December 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia

7 April 2017

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Sonic Hedgehog influences the balance of osteogenesis and adipogenesis in mouse adipose-derived stromal cells

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29 September 2017

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Conditional disruption of Pkd1 in osteoblasts results in osteopenia due to direct impairment of bone formation.

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Mechanical loading down-regulates peroxisome proliferator-activated receptor gamma in bone marrow stromal cells and favors osteoblastogenesis at the expense of adipogenesis

29 September 2017

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29 September 2017

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Polycystin-2 cation channel function is under the control of microtubular structures in primary cilia of renal epithelial cells.

29 September 2017

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29 September 2017

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Selective Runx2-II deficiency leads to low-turnover osteopenia in adult mice

29 September 2017

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Polycystins, calcium signaling, and human diseases.

29 September 2017

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Kidney-specific inactivation of the KIF3A subunit of kinesin-II inhibits renal ciliogenesis and produces polycystic kidney disease

29 September 2017

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Rescue of the skeletal phenotype in CasR-deficient mice by transfer onto the Gcm2 null background

29 September 2017

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Polaris, a protein disrupted in orpk mutant mice, is required for assembly of renal cilium

29 September 2017

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Characterization of the upstream mouse Cbfa1/Runx2 promoter

29 September 2017

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Sonic hedgehog increases the commitment of pluripotent mesenchymal cells into the osteoblastic lineage and abolishes adipocytic differentiation

29 September 2017

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29 September 2017

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29 September 2017

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KIF3A is a new microtubule-based anterograde motor in the nerve axon

29 September 2017

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The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization

29 September 2017

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Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity

2 June 2018

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Conditional Kif3a ablation causes abnormal hedgehog signaling topography, growth plate dysfunction, and excessive bone and cartilage formation during mouse skeletogenesis

2 June 2018

1 reference

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Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996304

Hedgehog signaling plays a conserved role in inhibiting fat formation

2 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996304

Transcription suppression of peroxisome proliferator-activated receptor gamma2 gene expression by tumor necrosis factor alpha via an inhibition of CCAAT/ enhancer-binding protein delta during the early stage of adipocyte differentiation.

2 June 2018

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Function of GATA transcription factors in preadipocyte-adipocyte transition

2 June 2018

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Development of the post-natal growth plate requires intraflagellar transport proteins

2 June 2018

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Role of intraflagellar transport and primary cilia in skeletal development.

21 January 2018

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Hedgehog signaling in mature osteoblasts regulates bone formation and resorption by controlling PTHrP and RANKL expression.

21 January 2018

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Hedgehog coordination of postnatal osteoclast and osteoblast activities

21 January 2018

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Intraflagellar transport is essential for endochondral bone formation

21 January 2018

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Oxysterols are novel activators of the hedgehog signaling pathway in pluripotent mesenchymal cells

21 January 2018

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Cellular and subcellular localization of the ARPKD protein; fibrocystin is expressed on primary cilia.

21 January 2018

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Osteogenic and adipogenic cell fractions isolated from postnatal mouse calvaria

21 January 2018

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Trans-heterozygous Pkd1 and Pkd2 mutations modify expression of polycystic kidney disease.

21 January 2018

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Selective deficiency of the "bone-related" Runx2-II unexpectedly preserves osteoblast-mediated skeletogenesis.

21 January 2018

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Molecular switching of osteoblastogenesis versus adipogenesis: implications for targeted therapies

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12 December 2020

Pathogenic sequence for dissecting aneurysm formation in a hypomorphic polycystic kidney disease 1 mouse model

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Polycystin-1 and -2 Dosage Regulates Pressure Sensing

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Gli2 activator function in preosteoblasts is sufficient to mediate Ihh-dependent osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification

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A signal transduction pathway involved in microtubule-mediated cell polarization

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12 December 2020

Comparison of Pkd1-targeted mutants reveals that loss of polycystin-1 causes cystogenesis and bone defects

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12 December 2020

Polycystic kidney disease

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A functional floxed allele of Pkd1 that can be conditionally inactivated in vivo

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[Cystic liver diseases. Genetics and cell biology]

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Polycystin-2 cation channel function in the human syncytiotrophoblast is regulated by microtubular structures

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12 December 2020

10.1371/JOURNAL.PONE.0015240

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1485937

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151991 AND SRC:MED&resulttype=core&format=json

OpenCitations bibliographic resource ID

18 January 2020

ADS bibcode

2010PLoSO...515240Q

0 references

1485937

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151991 AND SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

21151991

1 reference