Targeting pathogen metabolism without collateral damage to the host (Q28468608)

1

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10 June 2020

Amalia Dolga

3

1 reference

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10 June 2020

Freek J H Sorgdrager

4

1 reference

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10 June 2020

Balazs Szoor

9

1 reference

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10 June 2020

Keith Matthews

10

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10 June 2020

Hans Westerhoff

12

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10 June 2020

Barbara Marleen Bakker

13

1 reference

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10 June 2020

11

Jacky L Snoep

1 reference

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10 June 2020

author name string

Albert Gerding

2

1 reference

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10 June 2020

Manon Buist-Homan

5

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10 June 2020

François du Toit

6

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10 June 2020

Klaas Nico Faber

7

1 reference

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10 June 2020

Hermann-Georg Holzhütter

8

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10 June 2020

language of work or name

English

0 references

publication date

13 January 2017

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published in

Scientific Reports

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10 June 2020

volume

7

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10 June 2020

page(s)

40406

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Creative Commons Attribution 4.0 International

10 June 2020

copyright license

start time

13 January 2017

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

RTCA

object named as

RTCA

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

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Handling uncertainty in dynamic models: the pentose phosphate pathway in Trypanosoma brucei

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Targeting glycolysis in the malaria parasite Plasmodium falciparum

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An analysis of the attrition of drug candidates from four major pharmaceutical companies

29 September 2017

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SK channel activation modulates mitochondrial respiration and attenuates neuronal HT-22 cell damage induced by H2O2.

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Glycosomal targets for anti-trypanosomatid drug discovery

29 September 2017

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Quantifying the contribution of the liver to glucose homeostasis: a detailed kinetic model of human hepatic glucose metabolism

29 September 2017

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Structural approaches to obtain kinase selectivity

29 September 2017

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Drug resistance in human African trypanosomiasis

29 September 2017

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Predicting selective drug targets in cancer through metabolic networks.

29 September 2017

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Metabolic reconstruction, constraint-based analysis and game theory to probe genome-scale metabolic networks

29 September 2017

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The trypanolytic factor of human serum: many ways to enter the parasite, a single way to kill

29 September 2017

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Role of band 3 in regulating metabolic flux of red blood cells

29 September 2017

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Erythroid glucose transporters.

29 September 2017

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Human African trypanosomiasis: pharmacological re-engagement with a neglected disease.

29 September 2017

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The energy-less red blood cell is lost: erythrocyte enzyme abnormalities of glycolysis

29 September 2017

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Experimental and in silico analyses of glycolytic flux control in bloodstream form Trypanosoma brucei

29 September 2017

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Validation of the hexose transporter of Plasmodium falciparum as a novel drug target.

29 September 2017

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Contribution of glucose transport to the control of the glycolytic flux in Trypanosoma brucei

29 September 2017

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Cytochalasin B binding sites and glucose transport carrier in human erythrocyte ghosts

29 September 2017

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Model of 2,3-bisphosphoglycerate metabolism in the human erythrocyte based on detailed enzyme kinetic equations: computer simulation and metabolic control analysis

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A domino effect in drug action: from metabolic assault towards parasite differentiation.

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The principle of flux minimization and its application to estimate stationary fluxes in metabolic networks.

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What Controls Glycolysis in Bloodstream FormTrypanosoma brucei?

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12 December 2020

Phloretin - an uncoupler and an inhibitor of mitochondrial oxidative phosphorylation

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12 December 2020

Vectors for inducible expression of toxic gene products in bloodstream and procyclic Trypanosoma brucei

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12 December 2020

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Proliferating bloodstream-form Trypanosoma brucei use a negligible part of consumed glucose for anabolic processes

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Human erythrocytes express GLUT5 and transport fructose

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12 December 2020

Use of mathematical models for predicting the metabolic effect of large-scale enzyme activity alterations. Application to enzyme deficiencies of red blood cells

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12 December 2020

Structure of cytochalasins and cytochalasin B binding sites in human erythrocyte membranes

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Specificity of glucose transport in Trypanosoma brucei. Effective inhibition by phloretin and cytochalasin B

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12 December 2020

Identifiers

DOI

10.1038/SREP40406

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28084422 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28084422 AND SRC:MED&resulttype=core&format=json

10 June 2020

PubMed publication ID

28084422

1 reference