Genetic Ablation of CXCR2 Protects against Cigarette Smoke-Induced Lung Inflammation and Injury (Q28392432)

CXCR1/CXCR2 antagonist CXCL8(3-74)K11R/G31P blocks lung inflammation in swine barn dust-instilled mice

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7

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391

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cites work

1 reference

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Chemokine signaling via the CXCR2 receptor reinforces senescence

20 March 2017

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Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect

20 March 2017

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p53- and PAI-1-mediated induction of C-X-C chemokines and CXCR2: importance in pulmonary inflammation due to cigarette smoke exposure

20 March 2017

1 reference

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Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease

29 September 2017

1 reference

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Inhibition of LPS-induced airway neutrophilic inflammation in healthy volunteers with an oral CXCR2 antagonist.

29 September 2017

1 reference

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Chemokine receptor CXCR2 is transactivated by p53 and induces p38-mediated cellular senescence in response to DNA damage.

29 September 2017

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SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice

29 September 2017

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DNA damage‐dependent NF‐κB activation: NEMO turns nuclear signaling inside out

29 September 2017

1 reference

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Defective regulation of CXCR2 facilitates neutrophil release from bone marrow causing spontaneous inflammation in severely NF-kappa B-deficient mice

29 September 2017

1 reference

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CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow

29 September 2017

1 reference

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Aging enhances susceptibility to cigarette smoke-induced inflammation through bronchiolar chemokines

29 September 2017

1 reference

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Therapeutic inhibition of CXCR2 by Reparixin attenuates acute lung injury in mice

29 September 2017

1 reference

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A novel, orally active CXCR1/2 receptor antagonist, Sch527123, inhibits neutrophil recruitment, mucus production, and goblet cell hyperplasia in animal models of pulmonary inflammation

29 September 2017

1 reference

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Cigarette smoke induces cellular senescence

29 September 2017

1 reference

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Critical role of endothelial CXCR2 in LPS-induced neutrophil migration into the lung

29 September 2017

1 reference

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Role of CXCR2 in cigarette smoke-induced lung inflammation

29 September 2017

1 reference

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On the mechanism and significance of ligand-induced internalization of human neutrophil chemokine receptors CXCR1 and CXCR2.

29 September 2017

1 reference

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Critical role for CXCR2 and CXCR2 ligands during the pathogenesis of ventilator-induced lung injury

29 September 2017

1 reference

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CXCR2 is required for neutrophilic airway inflammation and hyperresponsiveness in a mouse model of human rhinovirus infection

29 September 2017

1 reference

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Attenuation of acute lung inflammation induced by cigarette smoke in CXCR3 knockout mice

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078490

Acute pulmonary inflammation is inhibited in CXCR3 knockout mice after short-term cigarette smoke exposure

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078490

Role of the chemokine receptor CXCR2 in bleomycin-induced pulmonary inflammation and fibrosis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5078490

CXCR2 is essential for maximal neutrophil recruitment and methacholine responsiveness after ozone exposure

2 June 2018

1 reference

https://api.crossref.org/works/10.3389/FPHAR.2016.00391

CXCR2 inhibition suppresses hemorrhage-induced priming for acute lung injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHAR.2016.00391

Neutrophil-derived ROS contribute to oxidative DNA damage induction by quartz particles

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHAR.2016.00391

CXCR2 is required for neutrophil recruitment to the lung during influenza virus infection, but is not essential for viral clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHAR.2016.00391

Disruption of neutrophil migration in a conditional transgenic model: evidence for CXCR2 desensitization in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHAR.2016.00391

HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27826243

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

An age-associated increase in pulmonary inflammation after burn injury is abrogated by CXCR2 inhibition

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27826243