Zinc and zinc transporter regulation in pancreatic islets and the potential role of zinc in islet transplantation (Q28390590)

Europe PubMed Central

title

Zinc and zinc transporter regulation in pancreatic islets and the potential role of zinc in islet transplantation (English)

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author name string

Mariea D Bosco

1

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Daisy M Mohanasundaram

2

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Chris J Drogemuller

3

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Carol J Lang

4

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Peter D Zalewski

5

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P Toby Coates

The review of diabetic studies : RDS

6

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language of work or name

English

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publication date

2010

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published in

1 reference

Inhibition of xanthine oxidase reduces oxidative stress and improves skeletal muscle function in response to electrically stimulated isometric contractions in aged mice

volume

7

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issue

4

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page(s)

263-74

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cites work

1 reference

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20 March 2017

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Functional characterization of a novel mammalian zinc transporter, ZnT6

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Gene therapy to improve pancreatic islet transplantation for Type 1 diabetes mellitus

29 September 2017

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Three-dimensional structure of beta-cell-specific zinc transporter, ZnT-8, predicted from the type 2 diabetes-associated gene variant SLC30A8 R325W.

29 September 2017

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Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic beta-cell function

29 September 2017

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TRPM3 channels provide a regulated influx pathway for zinc in pancreatic beta cells.

29 September 2017

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A low-risk ZnT-8 allele (W325) for post-transplantation diabetes mellitus is protective against cyclosporin A-induced impairment of insulin secretion

29 September 2017

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ZnT8 autoantibody titers in type 1 diabetes patients decline rapidly after clinical onset

29 September 2017

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29 September 2017

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STAT5-glucocorticoid receptor interaction and MTF-1 regulate the expression of ZnT2 (Slc30a2) in pancreatic acinar cells

29 September 2017

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Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.

29 September 2017

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Transient oxidative stress damages mitochondrial machinery inducing persistent beta-cell dysfunction

29 September 2017

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29 September 2017

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SLC30A3 responds to glucose- and zinc variations in beta-cells and is critical for insulin production and in vivo glucose-metabolism during beta-cell stress.

29 September 2017

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Effect of zinc supplementation on microalbuminuria in patients with type 2 diabetes: a double blind, randomized, placebo-controlled, cross-over trial

29 September 2017

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29 September 2017

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A common nonsynonymous single nucleotide polymorphism in the SLC30A8 gene determines ZnT8 autoantibody specificity in type 1 diabetes

29 September 2017

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ZIP7-mediated intracellular zinc transport contributes to aberrant growth factor signaling in antihormone-resistant breast cancer Cells.

29 September 2017

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SLC30A8 (ZnT8) Polymorphism is Associated with Young Age at Type 1 Diabetes Onset

29 September 2017

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29 September 2017

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Investigation of transport mechanisms and regulation of intracellular Zn2 in pancreatic alpha-cells.

29 September 2017

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Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function

29 September 2017

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Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function

29 September 2017

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Human islet oxygen consumption rate and DNA measurements predict diabetes reversal in nude mice

29 September 2017

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Oxidative stress and impaired insulin secretion in type 2 diabetes

29 September 2017

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Interventional strategies to prevent beta-cell apoptosis in islet transplantation.

29 September 2017

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Zinc-ligand interactions modulate assembly and stability of the insulin hexamer -- a review

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Allelic variation in gene expression is common in the human genome

29 September 2017

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Antioxidant effects of zinc supplementation in Tunisians with type 2 diabetes mellitus

29 September 2017

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Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?

29 September 2017

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Interrelationships of key variables of human zinc homeostasis: relevance to dietary zinc requirements

29 September 2017

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Zinc and selenium, site-specific versus general antioxidation.

29 September 2017

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Over-expression of ZnT7 increases insulin synthesis and secretion in pancreatic beta-cells by promoting insulin gene transcription

29 September 2017

1 reference

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Identification of a major humoral epitope in Slc30A8 (ZnT8).

2 June 2018

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Intracellular transport of proinsulin in pancreatic beta-cells. Structural maturation probed by disulfide accessibility

2 June 2018

1 reference

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Insulin sensitivity in zinc-depleted rats: assessment with the euglycaemic hyperinsulinic clamp technique.

2 June 2018

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Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion.

2 June 2018

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Meta-analysis and functional effects of the SLC30A8 rs13266634 polymorphism on isolated human pancreatic islets

27 November 2018

1 reference

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Islet transplantation and antioxidant management: a comprehensive review

27 November 2018

1 reference

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The influence of zinc supplementation on the pancreas of streptozotocin-diabetic rats

27 November 2018

1 reference

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Zinc transporter-8 gene (SLC30A8) is associated with type 2 diabetes in Chinese

27 November 2018

1 reference

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Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study).

27 November 2018

1 reference

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Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the Insulin Resistance Atherosclerosis Family Study

27 November 2018

1 reference

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A Polymorphism in the Zinc Transporter Gene SLC30A8 Confers Resistance Against Posttransplantation Diabetes Mellitus in Renal Allograft Recipients

27 November 2018

1 reference

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Znt7 (Slc30a7)-deficient mice display reduced body zinc status and body fat accumulation

27 November 2018

1 reference

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Insulin secretion defects of human type 2 diabetic islets are corrected in vitro by a new reactive oxygen species scavenger

27 November 2018

1 reference

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Zinc transporter 7 is located in the cis-Golgi apparatus of mouse choroid epithelial cells

27 November 2018

1 reference

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Islet microvasculature in islet hyperplasia and failure in a model of type 2 diabetes.

27 November 2018

1 reference

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Zinc at pharmacologic concentrations affects cytokine expression and induces apoptosis of human peripheral blood mononuclear cells

27 November 2018

1 reference

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Single-donor, marginal-dose islet transplantation in patients with type 1 diabetes

27 November 2018

1 reference

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D-Glyceraldehyde causes production of intracellular peroxide in pancreatic islets, oxidative stress, and defective beta cell function via non-mitochondrial pathways

27 November 2018

1 reference

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The action mechanism of zinc(II) complexes with insulinomimetic activity in rat adipocytes

27 November 2018

1 reference

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Zinc modulates mRNA levels of cytokines

27 November 2018

1 reference

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Insulin independence following isolated islet transplantation and single islet infusions

27 November 2018

1 reference

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Allelic Variation in Human Gene Expression

27 November 2018

1 reference

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Beta-cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemia

27 November 2018

1 reference

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The antioxidant properties of zinc: interactions with iron and antioxidants

27 November 2018

1 reference

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Trace element homeostasis during continuous sedation with propofol containing EDTA versus other sedatives in critically ill patients.

27 November 2018

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Survey of mRNAs encoding zinc transporters and other metal complexing proteins in pancreatic islets of rats from birth to adulthood: similar patterns in the Sprague-Dawley and Wistar BB strains.

27 November 2018

1 reference

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The molecular basis for the role of zinc in developmental biology

27 November 2018

1 reference

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Modulation of p53 protein conformation and DNA-binding activity by intracellular chelation of zinc.

27 November 2018

1 reference

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Effects of zinc supplementation on the plasma glucose level and insulin activity in genetically obese (ob/ob) mice.

27 November 2018

1 reference

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Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues.

27 November 2018

1 reference

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Destruction of islet isografts by severe nonspecific inflammation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143541

Autoantibodies to zinc transporter 8 and SLC30A8 genotype stratify type 1 diabetes risk

27 November 2018

1 reference

12 December 2020

Detection of secretion from single pancreatic beta-cells using extracellular fluorogenic reactions and confocal fluorescence microscopy

1 reference

12 December 2020

The pancreas and zinc homeostasis

1 reference

12 December 2020

siRNA-mediated knock-down of ZnT3 and ZnT8 affects production and secretion of insulin and apoptosis in INS-1E cells

1 reference

12 December 2020

Lymphoid expression and regulation of A20, an inhibitor of programmed cell death

1 reference

12 December 2020

Short-term zinc supplementation in women with non-insulin-dependent diabetes mellitus: effects on plasma 5'-nucleotidase activities, insulin-like growth factor I concentrations, and lipoprotein oxidation rates in vitro

1 reference

12 December 2020

Zinc sulphate induces metallothionein in pancreatic islets of mice and protects against diabetes induced by multiple low doses of streptozotocin

1 reference

12 December 2020

Letter: Acrodermatitis enteropathica: a lethal inherited human zinc-deficiency disorder

1 reference

12 December 2020

The cellular and subcellular localization of zinc transporter 7 in the mouse spinal cord

1 reference

12 December 2020

Evidence for a role of superoxide generation in glucose-induced beta-cell dysfunction in vivo

1 reference

12 December 2020

Zinc mapping and density imaging of rabbit pancreas endocrine tissue sections using nuclear microscopy

1 reference

12 December 2020

Zinc Therapy of Acrodermatitis Enteropathica

1 reference

12 December 2020

Zinc-transporter genes in human visceral and subcutaneous adipocytes: lean versus obese

1 reference

12 December 2020