Evaluation of the neuroactive steroid ganaxolone on social and repetitive behaviors in the BTBR mouse model of autism (Q28383216)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26525567 AND SRC:MED&resulttype=core&format=json

6 June 2020

Michael A Rogawski

series ordinal

4

1 reference

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6 June 2020

2

Randi J Hagerman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26525567 AND SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Tatiana M Kazdoba

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26525567 AND SRC:MED&resulttype=core&format=json

6 June 2020

Jacqueline N Crawley

series ordinal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26525567 AND SRC:MED&resulttype=core&format=json

6 June 2020

language of work or name

English

0 references

publication date

January 2016

0 references

published in

Psychopharmacology

1 reference

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6 June 2020

volume

233

1 reference

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6 June 2020

issue

2

1 reference

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6 June 2020

page(s)

309-323

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26525567 AND SRC:MED&resulttype=core&format=json

GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

6 June 2020

cites work

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Acute dietary tryptophan manipulation differentially alters social behavior, brain serotonin and plasma corticosterone in three inbred mouse strains

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AMPAKINE enhancement of social interaction in the BTBR mouse model of autism

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Neurosteroids — Endogenous Regulators of Seizure Susceptibility and Role in the Treatment of Epilepsy

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BTBR T tf/J mice: Autism-relevant behaviors and reduced fractone-associated heparan sulfate

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Density and function of central serotonin (5-HT) transporters, 5-HT1A and 5-HT2A receptors, and effects of their targeting on BTBR T tf/J mouse social behavior

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Recent developments in the significance and therapeutic relevance of neuroactive steroids--Introduction to the special issue

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Steroids, neuroactive steroids and neurosteroids in psychopathology

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Model of autism: increased ratio of excitation/inhibition in key neural systems

20 March 2017

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Autism-like behavioral phenotypes in BTBR T tf/J mice

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Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains

7 April 2017

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Autism Symptomatology in Boys with Fragile X Syndrome: A Cross Sectional Developmental Trajectories Comparison with Nonsyndromic Autism Spectrum Disorder

7 April 2017

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The fragile X syndrome-autism comorbidity: what do we really know?

29 September 2017

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Ganaxolone improves behavioral deficits in a mouse model of post-traumatic stress disorder

29 September 2017

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Sensory integration in mouse insular cortex reflects GABA circuit maturation

29 September 2017

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Chronic desipramine treatment rescues depression-related, social and cognitive deficits in Engrailed-2 knockout mice

29 September 2017

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Enhancement of inhibitory neurotransmission by GABAA receptors having α2,3-subunits ameliorates behavioral deficits in a mouse model of autism

29 September 2017

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Synergistic GABA-enhancing therapy against seizures in a mouse model of Dravet syndrome

29 September 2017

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Glyoxalase 1 and its substrate methylglyoxal are novel regulators of seizure susceptibility

29 September 2017

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Neurosteroids and GABA-A Receptor Function

29 September 2017

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Neuroendocrine aspects of catamenial epilepsy

29 September 2017

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Automated Three‐Chambered Social Approach Task for Mice

29 September 2017

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Prevalence of autism spectrum disorders in a total population sample

29 September 2017

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Social peers rescue autism-relevant sociability deficits in adolescent mice.

29 September 2017

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General and social anxiety in the BTBR T tf/J mouse strain.

29 September 2017

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Unusual repertoire of vocalizations in adult BTBR T tf/J mice during three types of social encounters

29 September 2017

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Expression of social behaviors of C57BL/6J versus BTBR inbred mouse strains in the visible burrow system

29 September 2017

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Ganaxolone suppression of behavioral and electrographic seizures in the mouse amygdala kindling model

29 September 2017

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Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP.

29 September 2017

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Chromosome 15q11-13 duplication syndrome brain reveals epigenetic alterations in gene expression not predicted from copy number.

29 September 2017

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The amygdala, reward and emotion.

29 September 2017

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Social deficits in BTBR T tf/J mice are unchanged by cross-fostering with C57BL/6J mothers

29 September 2017

1 reference

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Endogenous neurosteroids regulate GABAA receptors through two discrete transmembrane sites

29 September 2017

1 reference

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Assessing autism-like behavior in mice: variations in social interactions among inbred strains

29 September 2017

1 reference

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Emotion and cognition: insights from studies of the human amygdala

29 September 2017

1 reference

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Neurosteroid modulation of GABAA receptors

29 September 2017

1 reference

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Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex

29 September 2017

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Association between a GABRB3 polymorphism and autism.

29 September 2017

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GABAergic mechanisms in epilepsy

29 September 2017

1 reference

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Anxiolytic and side-effect profile of LY354740: a potent, highly selective, orally active agonist for group II metabotropic glutamate receptors

29 September 2017

1 reference

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Characterization of the anticonvulsant properties of ganaxolone (CCD 1042; 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one), a selective, high-affinity, steroid modulator of the gamma-aminobutyric acid(A) receptor

29 September 2017

1 reference

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Neurosteroids and GABAA receptor function.

29 September 2017

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Baseline exploratory activity predicts anxiolytic responsiveness to diazepam in five mouse strains.

29 September 2017

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Exploratory behavior models of anxiety in mice

29 September 2017

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NMDA receptor antagonists and limbic status epilepticus: a comparison with standard anticonvulsants

29 September 2017

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Neurosteroids increase tonic GABAergic inhibition in the lateral section of the central amygdala in mice

29 September 2017

1 reference

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Symptoms of Autism in Males with Fragile X Syndrome: A Comparison to Nonsyndromic ASD Using Current ADI-R Scores

2 June 2018

1 reference

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D-Cycloserine improves sociability in the BTBR T Itpr3tf/J mouse model of autism spectrum disorders with altered Ras/Raf/ERK1/2 signaling

2 June 2018

1 reference

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Autism profiles of males with fragile X syndrome

2 June 2018

1 reference

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Anxiolytic and anticonvulsant activity of a synthetic neuroactive steroid Co 3-0593

2 June 2018

1 reference

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Central nervous system characterization of the new cholecystokininB antagonist LY288513.

2 June 2018

1 reference

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Comparative behavioral characterization of the neuroactive steroids 3α-OH,5α-pregnan-20-one and 3α-OH,5β-pregnan-20-one in rodents

2 June 2018

1 reference

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Anticonvulsant tolerance and withdrawal characteristics of benzodiazepine receptor ligands in different seizure models in mice. Comparison of diazepam, bretazenil and abecarnil.

2 June 2018

1 reference

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An analysis of autism in fifty males with the fragile X syndrome

2 June 2018

1 reference

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The use of a plus-maze to measure anxiety in the mouse

2 June 2018

1 reference

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Effects of diazepam on behavioural and antinociceptive responses to the elevated plus-maze in male mice depend upon treatment regimen and prior maze experience

2 June 2018

1 reference

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Anxiolytic effects of 3α-hydroxy-5α[β]-pregnan-20-one: endogenous metabolites of progesterone that are active at the GABAA receptor

2 June 2018

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2 June 2018

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Autistic behavior in young boys with fragile X syndrome

21 January 2018

1 reference

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Ethological comparison of the effects of diazepam and acute/chronic imipramine on the behaviour of mice in the elevated plus-maze

21 January 2018

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Behavioral effects of diazepam in the murine plus-maze: flumazenil antagonism of enhanced head dipping but not the disinhibition of open-arm avoidance

21 January 2018

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Effects of early postnatal allopregnanolone administration on elevated plus maze anxiety scores in adult male Wistar rats

21 January 2018

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Allopregnanolone regulates neurogenesis and depressive/anxiety-like behaviour in a social isolation rodent model of chronic stress

21 January 2018

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21 January 2018

Animal tests of anxiety

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Genotypic differences between C57BL/6 and A inbred mice in anxiolytic and sedative actions of diazepam

21 January 2018

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Acute and chronic effects of the synthetic neuroactive steroid, ganaxolone, against the convulsive and lethal effects of pentylenetetrazol in seizure-kindled mice: comparison with diazepam and valproate

21 January 2018

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Differences in anxiety-related behaviours and in sensitivity to diazepam in inbred and outbred strains of mice.

21 January 2018

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Pharmacological treatment of fragile X syndrome with GABAergic drugs in a knockout mouse model

21 January 2018

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Pharmacological profile of a 17β-heteroaryl-substituted neuroactive steroid

21 January 2018

1 reference

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Ethological analysis of cholecystokinin (CCKA and CCKB) receptor ligands in the elevated plus-maze test of anxiety in mice

21 January 2018

1 reference

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Impacts of facial identity and type of emotion on responses of amygdala neurons

21 January 2018

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The anxiolytic effect of acute ethanol or diazepam exposure is unaltered in mu-opioid receptor knockout mice

21 January 2018

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Differences in anxiety-related behavior and response to diazepam in BALB/cByJ and C57BL/6J strains of mice

21 January 2018

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Neurosteroids infusion into the CA1 hippocampal region on exploration, anxiety-like behaviour and aversive learning

21 January 2018

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Anticonvulsant activity of progesterone and neurosteroids in progesterone receptor knockout mice.

21 January 2018

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Anxiolytic activity of progesterone in progesterone receptor knockout mice.

21 January 2018

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Behaviorally Selective Effects of Neuroactive Steroids on Plus-Maze Anxiety in Mice

21 January 2018

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The behavioral phenotype in fragile X: symptoms of autism in very young children with fragile X syndrome, idiopathic autism, and other developmental disorders

21 January 2018

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Prototypical anxiolytics do not reduce anxiety-like behavior in the open field in C57BL/6J mice.

21 January 2018

1 reference

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Modification of behavioral effects of drugs in mice by neuroactive steroids

21 January 2018

1 reference

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Male mice emit distinct ultrasonic vocalizations when the female leaves the social interaction arena

21 January 2018

1 reference

https://api.crossref.org/works/10.1007/S00213-015-4115-7

Effects of gestational allopregnanolone administration in rats bred for high affective behavior.

21 January 2018

1 reference

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Reversal of behavioral effects of pentylenetetrazol by the neuroactive steroid ganaxolone

21 January 2018

1 reference

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10.1007/S00213-015-4115-7

27 November 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26525567 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26525567 AND SRC:MED&resulttype=core&format=json

6 June 2020

PubMed publication ID

26525567

1 reference