Human microglia convert l-tryptophan into the neurotoxin quinolinic acid (Q28379366)

2

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C A Wiley

3

0 references

E O Major

4

0 references

K Saito

5

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S P Markey

Effects of immune activation on quinolinic acid and neuroactive kynurenines in the mouse

6

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language of work or name

English

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publication date

1 December 1996

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published in

Biochemical Journal

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volume

320 ( Pt 2)

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page(s)

595-7

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cites work

1 reference

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Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease

20 March 2017

1 reference

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Human macrophages convert L-tryptophan into the neurotoxin quinolinic acid

20 March 2017

1 reference

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Neuroactive kynurenines in Lyme borreliosis

29 September 2017

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Inter-relationships between quinolinic acid, neuroactive kynurenines, neopterin and beta 2-microglobulin in cerebrospinal fluid and serum of HIV-1-infected patients

29 September 2017

1 reference

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Poliovirus induces indoleamine-2,3-dioxygenase and quinolinic acid synthesis in macaque brain

29 September 2017

1 reference

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Quinolinic acid in tumors, hemorrhage and bacterial infections of the central nervous system in children

29 September 2017

1 reference

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4-Chloro-3-hydroxyanthranilate, 6-chlorotryptophan and norharmane attenuate quinolinic acid formation by interferon-gamma-stimulated monocytes (THP-1 cells).

2 June 2018

1 reference

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Early appearance of type II astrocytes in developing human fetal brain

2 June 2018

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Human fetal astrocytes in culture support the growth of the neurotropic human polyomavirus, JCV.

2 June 2018

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Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status

2 June 2018

1 reference

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Mechanism of delayed increases in kynurenine pathway metabolism in damaged brain regions following transient cerebral ischemia

2 June 2018

1 reference

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A mechanism for increased quinolinic acid formation following acute systemic immune stimulation

27 November 2018

1 reference

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A mechanism of quinolinic acid formation by brain in inflammatory neurological disease. Attenuation of synthesis from L-tryptophan by 6-chlorotryptophan and 4-chloro-3-hydroxyanthranilate

27 November 2018

1 reference

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Quinolinic acid in the cerebrospinal fluid of children with symptomatic human immunodeficiency virus type 1 disease: relationships to clinical status and therapeutic response

27 November 2018

1 reference

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Cerebrospinal fluid nitrite/nitrate levels in neurologic diseases.

27 November 2018

1 reference

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Quantification of quinolinic acid in rat brain, whole blood, and plasma by gas chromatography and negative chemical ionization mass spectrometry: effects of systemic L-tryptophan administration on brain and blood quinolinic acid concentrations

27 November 2018

1 reference

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Kynurenine pathway enzymes in brain: responses to ischemic brain injury versus systemic immune activation

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8973572

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Increased levels of the excitotoxin quinolinic acid in spinal cord following contusion injury

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8973572