The 5-HT4 receptor: molecular cloning and pharmacological characterization of two splice variants (Q28368220)

2

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H T Kao

3

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M A Olsen

4

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T M Laz

5

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L E Schechter

6

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J A Bard

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P J Vaysse

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P R Hartig

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T A Branchek

Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization

10

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language of work or name

English

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publication date

15 June 1995

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published in

The EMBO Journal

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volume

14

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issue

12

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page(s)

2806-15

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cites work

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Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation

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Molecular cloning and functional expression of 5-HT1E-like rat and human 5-hydroxytryptamine receptor genes

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Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase

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Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase

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Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane A2 receptor

20 March 2017

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International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin)

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Two members of a distinct subfamily of 5-hydroxytryptamine receptors differentially expressed in rat brain

20 March 2017

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A simple and very efficient method for generating cDNA libraries

20 March 2017

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

20 March 2017

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The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor

20 March 2017

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Palmitoylation of the human beta 2-adrenergic receptor. Mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor

20 March 2017

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Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase

20 March 2017

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Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor

20 March 2017

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Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype

20 March 2017

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Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1D alpha and 5-HT1D beta

20 March 2017

1 reference

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Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers

20 March 2017

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Human gene S31 encodes the pharmacologically defined serotonin 5-hydroxytryptamine1E receptor

20 March 2017

1 reference

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A human serotonin 1D receptor variant (5HT1D beta) encoded by an intronless gene on chromosome 6

20 March 2017

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Isolation of a mouse "5HT1E-like" serotonin receptor expressed predominantly in hippocampus

20 March 2017

1 reference

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Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype

20 March 2017

1 reference

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Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs

20 March 2017

1 reference

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Cloning and functional characterization of the rat stomach fundus serotonin receptor

20 March 2017

1 reference

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Molecular cloning, functional expression, and pharmacological characterization of a novel serotonin receptor (5-hydroxytryptamine2F) from rat stomach fundus

20 March 2017

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

20 March 2017

1 reference

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A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells

7 April 2017

1 reference

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Use of eukaryotic expression technology in the functional analysis of cloned genes

7 April 2017

1 reference

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Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.

7 April 2017

1 reference

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A proposed new nomenclature for 5-HT receptors.

29 September 2017

1 reference

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29 September 2017

1 reference

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Human serotonin1B receptor expression in Sf9 cells: phosphorylation, palmitoylation, and adenylyl cyclase inhibition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

The two isoforms of the mouse somatostatin receptor (mSSTR2A and mSSTR2B) differ in coupling efficiency to adenylate cyclase and in agonist-induced receptor desensitization

29 September 2017

1 reference

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A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model

29 September 2017

1 reference

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Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain

29 September 2017

1 reference

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Molecular characterization of a functional cDNA encoding the serotonin 1c receptor

29 September 2017

1 reference

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An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins

29 September 2017

1 reference

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Structure and functional expression of cloned rat serotonin 5HT-2 receptor

29 September 2017

1 reference

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The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

A 5-hydroxytryptamine receptor in human atrium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Cloning, functional expression, and mRNA tissue distribution of the rat 5-hydroxytryptamine1A receptor gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Molecular cloning and characterization of a rat brain cDNA encoding a 5-hydroxytryptamine1B receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Primary structure and functional expression of the 5HT3 receptor, a serotonin-gated ion channel

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

The 5-HT4 receptor: a place in the sun

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Characterization of the human 5-hydroxytryptamine1B receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Molecular cloning of a complementary deoxyribonucleic acid encoding the thyrotropin-releasing hormone receptor and regulation of its messenger ribonucleic acid in rat GH cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Sequence alignment of the G-protein coupled receptor superfamily

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Inhibition of cloned adenylyl cyclases by mutant-activated Gi-alpha and specific suppression of type 2 adenylyl cyclase inhibition by phorbol ester treatment.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Development of a radioligand binding assay for 5-HT4 receptors in guinea-pig and rat brain

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Differential expression of the beta-adrenergic receptor modifies agonist stimulation of adenylyl cyclase: a quantitative evaluation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

The effects of SB 204070, a highly potent and selective 5-HT4 receptor antagonist, on guinea-pig distal colon.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

The infectivity of polyoma virus DNA for mouse embryo cells in the presence of diethylaminoethyl-dextran

2 June 2018

1 reference

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Identification of serotonin M-receptor subtypes and their specific blockade by a new class of drugs

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Pharmacological characterization of two 5-hydroxytryptamine receptors coupled to adenylate cyclase in guinea pig hippocampal membranes.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

A nonclassical 5-hydroxytryptamine receptor positively coupled with adenylate cyclase in the central nervous system

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Expression of a human cDNA encoding the beta 2-adrenergic receptor in Chinese hamster fibroblasts (CHW): functionality and regulation of the expressed receptors.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Pharmacological characterization of a neuronal receptor for 5-hydroxytryptamine in guinea pig ileum with properties similar to the 5-hydroxytryptamine receptor.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Pharmacological characterization of 5-hydroxytryptamine4(5-HT4) receptors positively coupled to adenylate cyclase in adult guinea pig hippocampal membranes: effect of substituted benzamide derivatives.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Pharmacological analysis of 5-hydroxytryptamine effects on electrically stimulated human isolated urinary bladder

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

The rat 5-hydroxytryptamine1B receptor is the species homologue of the human 5-hydroxytryptamine1D beta receptor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Cloning and expression of an adenylyl cyclase localized to the corpus striatum

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

[3H]-GR113808 labels 5-HT4 receptors in the human and guinea-pig brain.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Cloning and expression of a novel mouse somatostatin receptor (SSTR2B).

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=398399

Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity

27 November 2018

1 reference

12 December 2020

Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: studies of bicyclic cannabinoid analogs

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12 December 2020

BRL 24924: a potent agonist at a non-classical 5-HT receptor positively coupled with adenylate cyclase in colliculi neurons

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12 December 2020

5-Hydroxytryptamine4 receptors mediate relaxation of the rat oesophageal tunica muscularis mucosae

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12 December 2020

Serotonin-induced stimulation of cortisol secretion from human adrenocortical tissue is mediated through activation of a serotonin4 receptor subtype

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12 December 2020