Effect of analogues of 5'-methylthioadenosine on cellular metabolism. Inactivation of S-adenosylhomocysteine hydrolase by 5'-isobutylthioadenosine (Q28366549)

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Language	Label	Description	Also known as
English	Effect of analogues of 5'-methylthioadenosine on cellular metabolism. Inactivation of S-adenosylhomocysteine hydrolase by 5'-isobutylthioadenosine	scientific article

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scholarly article

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Effect of analogues of 5'-methylthioadenosine on cellular metabolism. Inactivation of S-adenosylhomocysteine hydrolase by 5'-isobutylthioadenosine (English)

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author name string

F Della Ragione

1

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A E Pegg

2

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language of work or name

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publication date

15 February 1983

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Biochemical Journal

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210

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2

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429-35

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The enzymatic synthesis of S-adenosyl-L-homocysteine from adenosine and homocysteine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

20 March 2017

Studies of inhibition of rat spermidine synthase and spermine synthase

1 reference

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20 March 2017

Effects of inhibitors of spermidine and spermine synthesis on polyamine concentrations and growth of transformed mouse fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

20 March 2017

Affinity-chromatographic purification of S-adenosyl-l-homocysteine hydrolase. Some properties of the enzyme from rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

20 March 2017

Effect of 5‘-deoxy-5’-isobutylthioadenosine on putrescine uptake and polyamine biosynthesis by chick embryo fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

20 March 2017

5-Methylthioribose 1-phosphate: A product of partially purified, rat liver 5′-methylthioadenosine phosphorylase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

20 March 2017

Studies on the metabolism of 5'-isobutylthioadenosine (SIBA): phosphorolytic cleavage by methylthioadenosine phosphorylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

20 March 2017

S-Adenosyl-L-methionine-dependent macromolecule methyltransferases: potential targets for the design of chemotherapeutic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

29 September 2017

Trends in the biochemical pharmacology of 5'-deoxy-5'-methylthioadenosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

29 September 2017

Resistance of an adenosine kinase-deficient human lymphoblastoid cell line to effects of deoxyadenosine on growth, S-adenosylhomocysteine hydrolase inactivation, and dATP accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

29 September 2017

Reaction of 5'-deoxyadenosine and related analogs with the 5'-methylthioadenosine cleaving enzyme of sarcoma 180 cells, a possible chemotherapeutic target enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

29 September 2017

Apparent suicide inactivation of human lymphoblast S-adenosylhomocysteine hydrolase by 2'-deoxyadenosine and adenine arabinoside. A basis for direct toxic effects of analogs of adenosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

29 September 2017

Relationship between inhibition of protein methylase I and inhibition of Rous sarcoma virus-induced cell transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

29 September 2017

S -Adenosylhomocysteine toxicity in normal and adenosine kinase-deficient lymphoblasts of human origin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

29 September 2017

The antifungal antibiotic sinefungin as a ver y active inhibitor of methyltransferases and of the transformation of chick embryo fibroblasts by rous sarcoma virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

29 September 2017

Identification of 2-keto-4-methylthiobutyrate as an intermediate compound in methionine synthesis from 5'-methylthioadenosine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

2 June 2018

Methylthioadenosine, a potent inhibitor of spermine synthase from bovine brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

2 June 2018

Inhibition of the synthesis of polyamines and macromolecules by 5'-methylthioadenosine and 5'-alkylthiotubercidins in BHK21 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1154241

27 November 2018

Polyamine biosynthesis in rat prostate. Substrate and inhibitor properties of 7-deaza analogues of decarboxylated S-adenosylmethionine and 5'-methylthioadenosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/6407475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of S-adenosylhomocysteine in adenosine-mediated toxicity in cultured mouse T lymphoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/6407475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The rate of transmethylation in mouse liver as measured by trapping S-adenosylhomocysteine

1 reference

https://pubmed.ncbi.nlm.nih.gov/6407475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory activity of sinefungin and SIBA (5'-deoxy-5'-S-isobutylthio-adenosine) on the growth of promastigotes and amastigotes of different species of Leishmania

1 reference

https://pubmed.ncbi.nlm.nih.gov/6407475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal regulation of methylthioadenosine and polyamine metabolism in methylthioadenosine phosphorylase-deficient human leukemic cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/6407475

12 December 2020

based on heuristic

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Inhibition of cyclic amp phosphodiesterase by 5'-deoxy-5'-S-isobutylthioadenosine at biologically active concentrations of drug

1 reference

https://pubmed.ncbi.nlm.nih.gov/6407475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5'-Methylthioadenosine phosphorylase-L. Substrate activity of 5'-deoxyadenosine with the enzyme from Sarcoma 180 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/6407475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irreversible inhibition of S-adenosylhomocysteine hydrolase by nucleoside analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/6407475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of S-adenosylhomocysteine hydrolase by 5'-deoxy-5'-methylthioadenosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/6407475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of a methyl-transferase inhibitor, 5'-deoxy'5'-S-isobutyl-thioadenosine (SIBA) on cAMP level and progesterone induced meiosis reinitiation in Xenopus laevis oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/6407475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dependence of adenine production upon polyamine synthesis in cultured human lymphoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/6407475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of adenosine metabolites on methyltransferase reactions in isolated rat livers

1 reference

https://pubmed.ncbi.nlm.nih.gov/6407475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of S-adenosylhomocysteine hydrolase by 9-beta-D-arabinofuranosyladenine in intact cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/6407475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine metabolism: modification by S-adenosylhomocysteine and 5'-methylthioadenosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/6407475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of aminopropyltransferases by 5'-S-isobutyl-5'-deoxyadenosine in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/6407475

12 December 2020

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Carbocyclic analogue of 3-deazaadenosine: a novel antiviral agent using S-adenosylhomocysteine hydrolase as a pharmacological target

1 reference

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12 December 2020

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Identifiers

10.1042/BJ2100429

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