Src-family tyrosine kinases, phosphoinositide 3-kinase and Gab1 regulate extracellular signal-regulated kinase 1 activation induced by the type A endothelin-1 G-protein-coupled receptor (Q28363296)

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Language	Label	Description	Also known as
English	Src-family tyrosine kinases, phosphoinositide 3-kinase and Gab1 regulate extracellular signal-regulated kinase 1 activation induced by the type A endothelin-1 G-protein-coupled receptor	scientific article

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scholarly article

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Src-family tyrosine kinases, phosphoinositide 3-kinase and Gab1 regulate extracellular signal-regulated kinase 1 activation induced by the type A endothelin-1 G-protein-coupled receptor (English)

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G protein-coupled receptor

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author name string

S Bisotto

1

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E D Fixman

2

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language of work or name

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publication date

15 November 2001

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number of pages

9

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based on heuristic

inferred from page(s)

Biochemical Journal

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360

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Pt 1

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77-85

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Engagement of Gab1 and Gab2 in erythropoietin signaling

1 reference

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Src-family tyrosine kinases in activation of ERK-1 and p85/p110-phosphatidylinositol 3-kinase by G/CCKB receptors

1 reference

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20 March 2017

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

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A novel mitogenic signaling pathway of bradykinin in the human colon carcinoma cell line SW-480 involves sequential activation of a Gq/11 protein, phosphatidylinositol 3-kinase beta, and protein kinase Cepsilon

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Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast

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Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor

1 reference

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Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation

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A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

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Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

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EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

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The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase

1 reference

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29 September 2017

Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases

1 reference

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Extracellular signal-regulated kinases are involved in the antiapoptotic effect of endothelin-1.

1 reference

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An endothelin receptor B antagonist inhibits growth and induces cell death in human melanoma cells in vitro and in vivo

1 reference

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29 September 2017

The Gab1 protein is a docking site for multiple proteins involved in signaling by the B cell antigen receptor.

1 reference

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29 September 2017

Gab1 acts as an adapter molecule linking the cytokine receptor gp130 to ERK mitogen-activated protein kinase

1 reference

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Absence of endothelin receptors and receptor mRNA in mammalian fibroblasts transformed with SV40 or ras oncogene

1 reference

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Association of the Multisubstrate Docking Protein Gab1 with the Hepatocyte Growth Factor Receptor Requires a Functional Grb2 Binding Site Involving Tyrosine 1356

1 reference

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Efficient Cellular Transformation by the Met Oncoprotein Requires a Functional Grb2 Binding Site and Correlates with Phosphorylation of the Grb2-associated Proteins, Cbl and Gab1

1 reference

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1 reference

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Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases

1 reference

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The role of endothelin in coronary atherosclerosis

1 reference

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Phosphatidylinositol 3-kinase is an early intermediate in the G beta gamma-mediated mitogen-activated protein kinase signaling pathway

1 reference

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Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

1 reference

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Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway

1 reference

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Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation in intact Swiss 3T3 cells

1 reference

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29 September 2017

Molecular mechanisms of endothelin-1-induced cell-cycle progression: involvement of extracellular signal-regulated kinase, protein kinase C, and phosphatidylinositol 3-kinase at distinct points

1 reference

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2 June 2018

PI 3-kinase gamma and protein kinase C-zeta mediate RAS-independent activation of MAP kinase by a Gi protein-coupled receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222204

2 June 2018

Signal characteristics of G protein-transactivated EGF receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222204

2 June 2018

The IRS-signalling system during insulin and cytokine action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222204

2 June 2018

Differential regulation of extracellular signal-regulated protein kinase 1 and Jun N-terminal kinase 1 by Ca2 and protein kinase C in endothelin-stimulated Rat-1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222204

2 June 2018

Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222204

2 June 2018

cAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-activated protein kinase pathway in COS-7 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222204

2 June 2018

Identification of endothelin–1 in the pathophysiology of metastatic adenocarcinoma of the prostate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222204

2 June 2018

Cloning and expression of a cDNA encoding an endothelin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222204

2 June 2018

Gab1 mediates neurite outgrowth, DNA synthesis, and survival in PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222204

27 November 2018

Increasing complexity of Ras signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222204

27 November 2018

Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222204

27 November 2018

Extracellular matrix and pulmonary hypertension: control of vascular smooth muscle cell contractility

1 reference

https://pubmed.ncbi.nlm.nih.gov/11695994

12 December 2020

based on heuristic

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Levels of endothelin in the bronchoalveolar lavage fluid of patients with symptomatic asthma and reversible airflow obstruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/11695994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis of G protein specificity of human endothelin receptors. A study with endothelinA/B chimeras

1 reference

https://pubmed.ncbi.nlm.nih.gov/11695994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/11695994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear signaling by endothelin-1 requires Src protein-tyrosine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11695994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/11695994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of ERK activation attenuates endothelin-stimulated airway smooth muscle cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11695994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11695994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell growth control by G protein-coupled receptors: from signal transduction to signal integration

1 reference

https://pubmed.ncbi.nlm.nih.gov/11695994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A conserved inositol phospholipid binding site within the pleckstrin homology domain of the Gab1 docking protein is required for epithelial morphogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11695994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelin-1 inhibits apoptosis of vascular smooth muscle cells induced by nitric oxide and serum deprivation via MAP kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/11695994

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based on heuristic

inferred from PubMed ID database lookup

Requirement of SHP2 binding to Grb2-associated binder-1 for mitogen-activated protein kinase activation in response to lysophosphatidic acid and epidermal growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11695994

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/0264-6021:3600077

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