Decreased glucuronidation and increased bioactivation of acetaminophen in Gilbert's syndrome (Q28324425)

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:1732127

11 November 2022

J. P. Uetrecht

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:1732127

11 November 2022

P. G. Wells

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:1732127

full work available at URL

11 November 2022

language of work or name

English

0 references

publication date

February 1992

0 references

http://api.elsevier.com/content/article/PII:0016508592901069?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

http://api.elsevier.com/content/article/PII:0016508592901069?httpAccept=text/plain

11 November 2022

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

11 November 2022

0 references

102

0 references

issue

2

0 references

page(s)

577-86

0 references

cites work

Chronic nonhemolytic unconjugated hyperbilirubinemia with glucuronyl transferase deficiency. Clinical, biochemical, pharmacologic and genetic evidence for heterogeneity

1

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Hepatic Bilirubin UDP-Glucuronyl Transferase Activity in Liver Disease and Gilbert's Syndrome

11 November 2022

3

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Studies of bilirubin kinetics in normal adults

11 November 2022

9

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Diagnosis of Gilbert's Syndrome: Role of Reduced Caloric Intake Test

11 November 2022

13

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Constitutional hepatic dysfunction (CHD; Gilbert's disease); a review with special reference to a characteristic increase and prolongation of the hyperbilirubinemic response to nicotinic acid

11 November 2022

14

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Comparison of nicotinic acid- and caloric restriction-induced hyperbilirubinaemia in the diagnosis of Gilbert's syndrome

11 November 2022

15

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Gilbert's syndrome: diagnosis by typical serum bilirubin pattern

11 November 2022

20

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Relationships between serum bilirubins and production and conjugation of bilirubin. Studies in Gilbert's syndrome, Crigler-Najjar disease, hemolytic disorders, and rat models

11 November 2022

21

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

What can we learn from analysis of serum bilirubin?

11 November 2022

22

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

[On the problem of glucuronide formation in functional hyperbilirubinemia with regard to renal glucuronide clearance]

11 November 2022

23

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Alteration of drug metabolism in Gilbert's syndrome

11 November 2022

25

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Urinary glucuronic acid excretion in liver disease and the effect of a salicylamide load

11 November 2022

28

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Kinetics of Oxazepam and Lorazepam in Two Subjects with Gilbert Syndrome*

11 November 2022

29

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Glucuronide formation in patients with constitutional hepatic dysfunction (Gilbert's disease)

11 November 2022

30

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Conjugation of N-acetyl-p-aminophenol (N.A.P.A.) in adult liver patients

11 November 2022

31

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Normal pathways for glucuronidation, sulphation and oxidation of paracetamol in Gilbert's syndrome

11 November 2022

33

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Kinetics and metabolism of paracetamol and phenacetin

11 November 2022

35

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Inter-subject and ethnic differences in paracetamol metabolism

11 November 2022

36

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Enhanced acetaminophen toxicity in rats with bilirubin glucuronyl transferase deficiency

11 November 2022

38

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Studies on the genetic linkage of bilirubin and androsterone UDP-glucuronyltransferases by cross-breeding of two mutant rat strains

11 November 2022

41

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Isolation and sequencing of rat liver bilirubin UDP-glucuronosyltransferase cDNA: possible alternate splicing of a common primary transcript

11 November 2022

42

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Obesity, sex, and acetaminophen disposition

11 November 2022

44

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Repetitive microvolumetric sampling and analysis of acetaminophen and its toxicologically relevant metabolites in murine plasma and urine using high performance liquid chromatography

11 November 2022

45

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Heterogeneity of hepatic microsomal UDP-glucuronosyltransferase(s) activities: comparison between human and mammalian species activities.

11 November 2022

47

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Isolation of multiple normal and functionally defective forms of uridine diphosphate-glucuronosyltransferase from inbred Gunn rats

11 November 2022

48

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Paracetamol (acetaminophen) kinetics in patients with Gilber's syndrome

11 November 2022

49

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Paracetamol as a test drug to determine glucuronide formation in man. Effects of inducers and of smoking

11 November 2022

50

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Glucuronidation and biliary excretion of acetaminophen in rats

11 November 2022

51

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Is biliary excretion of paracetamol significant in man?

11 November 2022

52

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Dose-dependent pharmacokinetics of acetaminophen: evidence of glutathione depletion in humans.

11 November 2022

53

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Use of thermospray liquid chromatography-mass spectrometry for characterization of reactive metabolites of 3'-hydroxyacetanilide, a non-hepatotoxic regioisomer of acetaminophen

11 November 2022

55

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Paracetamol poisoning in children

11 November 2022

58

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

Acetaminophen elimination kinetics in neonates, children, and adults

11 November 2022

59

1 reference

https://api.crossref.org/works/10.1016/0016-5085(92)90106-9

11 November 2022

Identifiers

0 references