Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice (Q28312170)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19307728 AND SRC:MED&resulttype=core&format=json

24 January 2020

title

Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice (English)

1 reference

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24 January 2020

2

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24 January 2020

Michael Tsang

3

1 reference

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24 January 2020

Laurent Kodjabachian

4

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24 January 2020

Natalie A. Sims

5

1 reference

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24 January 2020

Mathias Ehrich

7

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24 January 2020

Alexander Dobrovic

8

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24 January 2020

Peter Choong

10

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24 January 2020

Peter Choong

11

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24 January 2020

David M Thomas

14

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24 January 2020

author name string

Maya Kansara

1

1 reference

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24 January 2020

Melanie K Trivett

6

1 reference

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24 January 2020

John Slavin

9

1 reference

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24 January 2020

Paul J Simmons

12

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24 January 2020

Igor B Dawid

13

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24 January 2020

language of work or name

English

0 references

publication date

23 March 2009

1 reference

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Journal of Clinical Investigation

24 January 2020

published in

1 reference

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24 January 2020

volume

119

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24 January 2020

issue

4

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24 January 2020

page(s)

837-851

1 reference

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Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer

24 January 2020

cites work

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Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry

20 March 2017

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Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis

20 March 2017

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The Wnt antagonist sFRP1 in colorectal tumorigenesis

20 March 2017

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High bone density due to a mutation in LDL-receptor-related protein 5

20 March 2017

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Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation

20 March 2017

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20 March 2017

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A new secreted protein that binds to Wnt proteins and inhibits their activities

20 March 2017

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

20 March 2017

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A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands

20 March 2017

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Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation

20 March 2017

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Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter

20 March 2017

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Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

20 March 2017

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Secreted antagonists of the Wnt signalling pathway

7 April 2017

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Improved retroviral vectors for gene transfer and expression

7 April 2017

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In vitro analysis of integrated global high-resolution DNA methylation profiling with genomic imbalance and gene expression in osteosarcoma

7 April 2017

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Roles of Wnt signalling in bone growth, remodelling, skeletal disorders and fracture repair.

29 September 2017

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Wnt pathway inhibitors are strongly down-regulated in pituitary tumors

29 September 2017

1 reference

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Mechanisms of anabolic therapies for osteoporosis

29 September 2017

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The genetics of low-density lipoprotein receptor-related protein 5 in bone: a story of extremes

29 September 2017

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Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton

29 September 2017

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Molecular pathogenesis of osteosarcoma.

29 September 2017

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The many ways of Wnt in cancer

29 September 2017

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WIF1, an inhibitor of the Wnt pathway, is rearranged in salivary gland tumors

29 September 2017

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Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia

29 September 2017

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Function and biological roles of the Dickkopf family of Wnt modulators

29 September 2017

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Epigenetic modifications in osteogenic differentiation and transformation.

29 September 2017

1 reference

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Inactivation of Wnt inhibitory factor-1 (WIF1) expression by epigenetic silencing is a common event in breast cancer.

29 September 2017

1 reference

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Epigenetic inactivation of Wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/beta-catenin signaling pathway

29 September 2017

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Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers.

29 September 2017

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Molecular profiling of giant cell tumor of bone and the osteoclastic localization of ligand for receptor activator of nuclear factor kappaB

29 September 2017

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Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma

29 September 2017

1 reference

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Reprogramming of a melanoma genome by nuclear transplantation

29 September 2017

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Cytoplasmic and/or nuclear staining of beta-catenin is associated with lung metastasis

29 September 2017

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Cytoplasmic and/or nuclear accumulation of the beta-catenin protein is a frequent event in human osteosarcoma

29 September 2017

1 reference

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Bone homeostasis in growth hormone receptor-null mice is restored by IGF-I but independent of Stat5.

29 September 2017

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DNA hypermethylation in tumorigenesis: epigenetics joins genetics

29 September 2017

1 reference

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CpG methylation within the 5' regulatory region of the BRCA1 gene is tumor specific and includes a putative CREB binding site

29 September 2017

1 reference

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Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

29 September 2017

1 reference

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Normal genetically mosaic mice produced from malignant teratocarcinoma cells

29 September 2017

1 reference

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Comprehensive microarray analysis of bone morphogenetic protein 2-induced osteoblast differentiation resulting in the identification of novel markers for bone development

29 September 2017

1 reference

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Sp1 elements protect a CpG island from de novo methylation

2 June 2018

1 reference

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Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1.

2 June 2018

1 reference

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Identification of genes differentially expressed by prematurely fused human sutures using a novel in vivo - in vitro approach

2 June 2018

1 reference

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Defining a noncarcinogenic dose of recombinant human parathyroid hormone 1-84 in a 2-year study in Fischer 344 rats.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662557

Bone anabolic effects of parathyroid hormone are blunted by deletion of the Wnt antagonist secreted frizzled-related protein-1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662557

An in vivo tumor model exploiting metabolic response as a biomarker for targeted drug development

27 November 2018

1 reference

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Perinatal testosterone surge is required for normal adult bone size but not for normal bone remodeling.

27 November 2018

1 reference

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Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation

27 November 2018

1 reference

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Sex and tissue-specific differences in low-dose radiation-induced oncogenic signaling

27 November 2018

1 reference

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Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2662557

Bone neoplasms in F344 rats given teriparatide [rhPTH(1-34)] are dependent on duration of treatment and dose

27 November 2018

1 reference

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Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors

27 November 2018

1 reference

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Stable suppression of tumorigenicity by virus-mediated RNA interference

27 November 2018

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DNA methylation represses transcription in vivo.

27 November 2018

1 reference

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Frequent beta-catenin abnormalities in bone and soft-tissue tumors.

27 November 2018

1 reference

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Differential cell surface expression of the STRO-1 and alkaline phosphatase antigens on discrete developmental stages in primary cultures of human bone cells.

27 November 2018

1 reference

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Mapping Patterns of CpG Island Methylation in Normal and Neoplastic Cells Implicates Both Upstream and Downstream Regions inde Novo Methylation

27 November 2018

1 reference

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Allele-specific expression and total expression levels of imprinted genes during early mouse development: implications for imprinting mechanisms

27 November 2018

1 reference

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Deletion of a single allele of the Dkk1 gene leads to an increase in bone formation and bone mass

27 November 2018

1 reference

12 December 2020

Functional analysis of CpG methylation in the BRCA1 promoter region

1 reference

12 December 2020

Clinical relevance of Ki-67 expression in bone tumors

1 reference

12 December 2020

Intermittent parathyroid hormone treatment increases osteoblast number, steady state messenger ribonucleic acid levels for osteocalcin, and bone formation in tibial metaphysis of hypophysectomized female rats

1 reference

12 December 2020

In SituHistochemical Detection ofβ-Galactosidase Activity in Lung: Assessment of X-Gal Reagent in DistinguishinglacZGene Expression and Endogenousβ-Galactosidase Activity

1 reference

12 December 2020

PARAMETERS OF RADIATION DOSAGE THAT INFLUENCE PRODUCTION OF OSTEOGENIC SARCOMAS IN MICE

1 reference

12 December 2020

An expression signature classifies chemotherapy-resistant pediatric osteosarcoma

1 reference

12 December 2020

Osteosarcoma and teriparatide?

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12 December 2020

Identifiers

DOI

10.1172/JCI37175

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19307728 AND SRC:MED&resulttype=core&format=json

release_tek2kwiymfby3cytzfdc3s37fm

24 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tek2kwiymfby3cytzfdc3s37fm

24 November 2022

mapped directly with Wikidata item

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19307728 AND SRC:MED&resulttype=core&format=json

24 January 2020

PubMed publication ID

19307728

2 references