Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway (Q28306490)

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English	Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway	scientific article

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scholarly article

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Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway (English)

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author name string

P Gerwins

1

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J L Blank

2

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G L Johnson

3

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language of work or name

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publication date

28 March 1997

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Journal of Biological Chemistry

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272

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13

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8288-95

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Sounding the alarm: protein kinase cascades activated by stress and inflammation

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Diversity in function and regulation of MAP kinase pathways

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

MAP kinase pathways in yeast: for mating and more

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21 January 2018

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

The stress-activated protein kinase subfamily of c-Jun kinases

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Components of a new human protein kinase signal transduction pathway

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Sequential protein kinase reactions controlling cell growth and differentiation

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Differential calcium dependence in the activation of c-Jun kinase and mitogen-activated protein kinase by muscarinic acetylcholine receptors in rat 1a cells

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Angiotensin II stimulates calcium-dependent activation of c-Jun N-terminal kinase

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Identification and characterization of a new mammalian mitogen-activated protein kinase kinase, MKK2.

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Isolation of MEK5 and differential expression of alternatively spliced forms

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Raf-1 activates MAP kinase-kinase

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

MEK-1 phosphorylation by MEK kinase, Raf, and mitogen-activated protein kinase: analysis of phosphopeptides and regulation of activity

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

The mixed lineage kinase SPRK phosphorylates and activates the stress-activated protein kinase activator, SEK-1.

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1).

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

A novel fluorescent ceramide analogue for studying membrane traffic in animal cells: accumulation at the Golgi apparatus results in altered spectral properties of the sphingolipid precursor

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Two binding orientations for peptides to the Src SH3 domain: development of a general model for SH3-ligand interactions

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Structure-function analysis of SH3 domains: SH3 binding specificity altered by single amino acid substitutions

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Structural basis for the binding of proline-rich peptides to SH3 domains

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

PH domain: the first anniversary

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Protein-DNA interactions at a drug-responsive element of the human apolipoprotein A-I gene

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Cdc42 and PAK-mediated signaling leads to Jun kinase and p38 mitogen-activated protein kinase activation

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

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https://api.crossref.org/works/10.1074/JBC.272.13.8288

21 January 2018

Identifiers

10.1074/JBC.272.13.8288

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