Mutation of the MXI1 gene in prostate cancer (Q28302634)

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A R Brothman

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B J Williams

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N B Atkin

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E V Prochownik

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

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language of work or name

English

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publication date

March 1995

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published in

Nature Genetics

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volume

9

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issue

3

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page(s)

249-55

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cites work

1 reference

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

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Assignment of the human MAD and MXI1 genes to chromosomes 2p12-p13 and 10q24-q25

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The SMC family: novel motor proteins for chromosome condensation?

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The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation

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An amino-terminal c-myc domain required for neoplastic transformation activates transcription

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The leucine zipper of c-Myc is required for full inhibition of erythroleukemia differentiation

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Intracellular leucine zipper interactions suggest c-Myc hetero-oligomerization

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Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max.

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Myc and Max proteins possess distinct transcriptional activities

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Sequence-specific transcriptional activation by Myc and repression by Max.

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The tumor suppressor genes

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Clonal expansion of p53 mutant cells is associated with brain tumour progression

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Translocation and rearrangements of the c-myc oncogene locus in human undifferentiated B-cell lymphomas

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Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma

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L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer

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The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

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MyoD family: a paradigm for development?

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Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo

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The myoD Gene Family: Nodal Point During Specification of the Muscle Cell Lineage

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Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc

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7 January 2021

Association of Myn, the murine homolog of Max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation

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Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity

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7 January 2021

Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites

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7 January 2021

Oncogenic activity of the c-Myc protein requires dimerization with Max.

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7 January 2021

Opposite regulation of gene transcription and cell proliferation by c-Myc and Max.

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7 January 2021

Suppression of Myc, but not E1a, transformation activity by Max-associated proteins, Mad and Mxi1

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7 January 2021

Translocation (2;7)(p13;q36) in a case of acute nonlymphocytic leukemia evolving from a myelodysplastic syndrome

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Chromosomal characteristics of malignant lymphoma

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B-cell chronic lymphocytic leukaemia: clonal chromosome abnormalities and prognosis in 89 cases

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Childhood chronic lymphocytic leukemia with (2;14) translocation

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Deletion mapping of the long arm of chromosome 10 in glioblastoma multiforme

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Chromosome study of five cancers of the prostate.

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Cytogenetic analysis of 57 primary prostatic adenocarcinomas

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Cytogenetic survey of 32 cancers of the prostate

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Tumor suppressor genes

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A simple method for isolation of DNA from formalin-fixed paraffin-embedded samples for PCR

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7 January 2021

Splicing of messenger RNA precursors

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7 January 2021

Differential patterns of DNA binding by myc and max proteins

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7 January 2021

Myogenin resides in the nucleus and acquires high affinity for a conserved enhancer element on heterodimerization

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7 January 2021

Discrimination between related DNA sites by a single amino acid residue of Myc-related basic-helix-loop-helix proteins

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7 January 2021

A point mutation in the MyoD basic domain imparts c-Myc-like properties

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Rapid and efficient site-specific mutagenesis without phenotypic selection

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7 January 2021

Aneusomy of chromosomes 7 and 17 detected by FISH in prostate cancer and the effects of selection in vitro

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