Progress towards in vivo use of siRNAs (Q28297652)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16481219 AND SRC:MED&resulttype=core&format=json

16 January 2020

review article

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title

Progress towards in vivo use of siRNAs (English)

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16 January 2020

1

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16 January 2020

author name string

Mark A Behlke

series ordinal

1

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language of work or name

English

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publication date

14 February 2006

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16 January 2020

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16 January 2020

volume

13

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issue

4

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16 January 2020

page(s)

644-670

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Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide

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A facile nonviral method for delivering genes and siRNAs to skeletal muscle of mammalian limbs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Small interfering RNA targeting Fas protects mice against renal ischemia-reperfusion injury.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Protection against lethal influenza virus challenge by RNA interference in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Use of RNA interference to prevent lethal murine west nile virus infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Targeting 2A protease by RNA interference attenuates coxsackieviral cytopathogenicity and promotes survival in highly susceptible mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

In vivo delivery of caspase-8 or Fas siRNA improves the survival of septic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Toward a gene therapy for dominant disease: validation of an RNA interference-based mutation-independent approach

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Sequence-specific suppression of mdr1a/1b expression in mice via RNA interference

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Gene silencing in primary and metastatic tumors by small interfering RNA delivery in mice: quantitative analysis using melanoma cells expressing firefly and sea pansy luciferases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Gene silencing in rat-liver and limb grafts by rapid injection of small interference RNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

RNA silencing in vivo reveals role of p22phox in rat angiotensin slow pressor response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Delivery of siRNA and siRNA expression constructs to adult mammals by hydrodynamic intravascular injection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Sequence-specific gene silencing in murine muscle induced by electroporation-mediated transfer of short interfering RNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Exploring RNA interference as a therapeutic strategy for renal disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

RNAi-induced gene silencing by local electroporation in targeting brain region.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Effects of treatment with small interfering RNA on joint inflammation in mice with collagen-induced arthritis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Electro-transfer of small interfering RNA ameliorated arthritis in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Sonoporation using microbubble BR14 promotes pDNA/siRNA transduction to murine heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Overcoming the inhibitory effect of serum on lipofection by increasing the charge ratio of cationic liposome to DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Comprehensive analysis of the acute toxicities induced by systemic administration of cationic lipid:plasmid DNA complexes in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Cytotoxicity issues pertinent to lipoplex-mediated gene therapy in-vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

In vivo characteristics of cationic liposomes as delivery vectors for gene therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

DOTAP (and other cationic lipids): chemistry, biophysics, and transfection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Side-effects of a systemic injection of linear polyethylenimine-DNA complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Effects of structure of beta-cyclodextrin-containing polymers on gene delivery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Self-assembling nucleic acid delivery vehicles via linear, water-soluble, cyclodextrin-containing polymers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Rapid intravascular injection into limb skeletal muscle: a damage assessment study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

In vivo gene silencing in Plasmodium berghei--a mouse malaria model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

An apolipoprotein B antisense oligonucleotide lowers LDL cholesterol in hyperlipidemic mice without causing hepatic steatosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Encapsulation of c-myc antisense oligodeoxynucleotides in lipid particles improves antitumoral efficacy in vivo in a human melanoma line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Transporting silence: design of carriers for siRNA to angiogenic endothelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Tumor-targeted gene therapy: strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Toll-like receptors on tumor cells facilitate evasion of immune surveillance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Inhibition of influenza virus production in virus-infected mice by RNA interference

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Gene silencing by systemic delivery of synthetic siRNAs in adult mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Suppression of ocular neovascularization with siRNA targeting VEGF receptor 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

End-capped antisense oligodeoxynucleotides effectively inhibit gene expression in vivo and offer a low-toxicity alternative to fully modified phosphorothioate oligodeoxynucleotides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

siRNA relieves chronic neuropathic pain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Lack of efficacy of 'naked' small interfering RNA applied directly to rat brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Central administration of small interfering RNAs in rats: a comparison with antisense oligonucleotides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Small interfering RNA targeting Raf-1 inhibits tumor growth in vitro and in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

DNA antisense therapy for asthma in an animal model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Discovery and development of respirable antisense therapeutics for asthma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Noninvasive delivery of small inhibitory RNA and other reagents to pulmonary alveoli in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Inhibition of respiratory viruses by nasally administered siRNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

A novel method for the intracellular delivery of siRNA using microbubble-enhanced focused ultrasound

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

First clinical data on RNAi

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Evaluating hypoxia-inducible factor-1alpha as a cancer therapeutic target via inducible RNA interference in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Blockage of the macrophage migration inhibitory factor expression by short interference RNA inhibited the rejection of an allogeneic tracheal graft

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Silencing T-bet defines a critical role in the differentiation of autoreactive T lymphocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Silencing of Fas, but not caspase-8, in lung epithelial cells ameliorates pulmonary apoptosis, inflammation, and neutrophil influx after hemorrhagic shock and sepsis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

In vivo gene silencing (with siRNA) of pulmonary expression of MIP-2 versus KC results in divergent effects on hemorrhage-induced, neutrophil-mediated septic acute lung injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Small interfering RNA-mediated functional silencing of vasopressin V2 receptors in the mouse kidney

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

siRNA-induced caveolin-1 knockdown in mice increases lung vascular permeability via the junctional pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Antitumor activity of small interfering RNA/cationic liposome complex in mouse models of cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Variants of bcl-2 specific siRNA for silencing antiapoptotic bcl-2 in pancreatic cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Characterization of the bystander effect of somatostatin receptor sst2 after in vivo gene transfer into human pancreatic cancer cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Down-regulation of apoptosis mediators by RNAi inhibits axotomy-induced retinal ganglion cell death in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

Attenuation of alpha2A-adrenergic receptor expression in neonatal rat brain by RNA interference or antisense oligonucleotide reduced anxiety in adulthood

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/J.YMTHE.2006.01.001

A randomized controlled clinical trial of intravitreous fomivirsen for treatment of newly diagnosed peripheral cytomegalovirus retinitis in patients with AIDS.

7 January 2021

1 reference

12 December 2020

Structural requirements of double-stranded RNA for the activation of 2‘,5‘-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells

1 reference

12 December 2020

In vivo application of RNA interference: from functional genomics to therapeutics

1 reference

12 December 2020

Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model.

1 reference

12 December 2020

RNA interference targeting transforming growth factor-beta type II receptor suppresses ocular inflammation and fibrosis.

1 reference

12 December 2020

State-of-the-art modified RNAi compounds for therapeutics.

1 reference

12 December 2020

Immunotherapeutic utility of stimulatory and suppressive oligodeoxynucleotides

1 reference

12 December 2020

Recent advances in immunostimulatory CpG oligonucleotides.

1 reference

12 December 2020

Antisense oligonucleotides for target validation in the CNS.

1 reference

12 December 2020

siRNA targeted against amyloid precursor protein impairs synaptic activity in vivo.

1 reference

12 December 2020

SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth.

1 reference

12 December 2020

Modification of professional antigen-presenting cells with small interfering RNA in vivo to enhance cancer vaccine potency

1 reference

12 December 2020

Systemic siRNA-mediated gene silencing: a new approach to targeted therapy of cancer.

1 reference

12 December 2020

Peptide-oligonucleotide conjugates for the delivery of antisense and siRNA.

1 reference

12 December 2020

Reconstituted influenza virus envelopes as an efficient carrier system for cellular delivery of small-interfering RNAs.

1 reference

12 December 2020

siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain

1 reference

12 December 2020

Peptide-Based Strategy for siRNA Delivery into Mammalian Cells

1 reference

12 December 2020

Potential applications for RNAi to probe pathogenesis and develop new treatments for ocular disorders

1 reference

12 December 2020

Small interfering RNA for experimental cancer therapy.

1 reference

12 December 2020

Requirement for sphingosine 1-phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference

1 reference

12 December 2020

Silencing of CXCR4 blocks breast cancer metastasis

1 reference

12 December 2020

Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo

1 reference

12 December 2020

Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells

1 reference

12 December 2020

Oligonucleotide analogues: an overview

1 reference

12 December 2020

Systemic delivery of RafsiRNA using cationic cardiolipin liposomes silences Raf-1 expression and inhibits tumor growth in xenograft model of human prostate cancer.

1 reference

12 December 2020

10.1016/J.YMTHE.2006.01.001

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16481219 AND SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017