Iron-regulatory proteins limit hypoxia-inducible factor-2alpha expression in iron deficiency (Q28297161)

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

21 April 2017

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Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway

21 April 2017

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Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

21 April 2017

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Iron regulation and the cell cycle: identification of an iron-responsive element in the 3'-untranslated region of human cell division cycle 14A mRNA by a refined microarray-based screening strategy

21 April 2017

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Translational regulation of mammalian and Drosophila citric acid cycle enzymes via iron-responsive elements

21 April 2017

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Iron-dependent regulation of the divalent metal ion transporter

21 April 2017

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Identification of the iron-responsive element for the translational regulation of human ferritin mRNA

21 April 2017

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 April 2017

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PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR

21 April 2017

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Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia

21 April 2017

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

21 April 2017

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The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling

21 April 2017

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Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

21 April 2017

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The HIF family member EPAS1/HIF-2α is required for normal hematopoiesis in mice

21 April 2017

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HIF-2alpha regulates murine hematopoietic development in an erythropoietin-dependent manner

21 April 2017

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Retinal disease in mice lacking hypoxia-inducible transcription factor-2alpha

21 April 2017

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The deadenylating nuclease (DAN) is involved in poly(A) tail removal during the meiotic maturation of Xenopus oocytes.

21 April 2017

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Oxygen sensing by HIF hydroxylases

21 April 2017

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Regulation of erythropoietin production

21 April 2017

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Increased duodenal iron uptake and transfer in a rat model of chronic hypoxia is accompanied by reduced hepcidin expression

21 January 2018

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HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 alpha and developmentally expressed in blood vessels

21 January 2018

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Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology

21 January 2018

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Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

21 January 2018

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Attenuation of proteasome-induced proteolysis in skeletal muscle by {beta}-hydroxy-{beta}-methylbutyrate in cancer-induced muscle loss

21 January 2018

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Balancing acts: molecular control of mammalian iron metabolism

21 January 2018

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IRP-1 Binding to Ferritin mRNA Prevents the Recruitment of the Small Ribosomal Subunit by the Cap-Binding Complex eIF4F

21 January 2018

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Role of the ferroportin iron-responsive element in iron and nitric oxide dependent gene regulation

21 January 2018

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Complete loss of iron regulatory proteins 1 and 2 prevents viability of murine zygotes beyond the blastocyst stage of embryonic development

21 January 2018

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Generation of conditional alleles of the murineiron regulatory protein (IRP)-1 and -2 genes

21 January 2018

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A model for the structure and functions of iron-responsive elements

21 January 2018

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Position is the critical determinant for function of iron-responsive elements as translational regulators

21 January 2018

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Ribosomal pausing and scanning arrest as mechanisms of translational regulation from cap-distal iron-responsive elements

21 January 2018

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Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

21 January 2018

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HLF/HIF-2alpha is a key factor in retinopathy of prematurity in association with erythropoietin

21 January 2018

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Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys

21 January 2018

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Recombinant iron-regulatory factor functions as an iron-responsive-element-binding protein, a translational repressor and an aconitase. A functional assay for translational repression and direct demonstration of the iron switch

21 January 2018

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Standardization of protocols in cDNA microarray analysis

21 January 2018

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Hypoxia post-translationally activates iron-regulatory protein 2.

21 January 2018

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Hypoxia alters iron-regulatory protein-1 binding capacity and modulates cellular iron homeostasis in human hepatoma and erythroleukemia cells

21 January 2018

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Effect of hypoxia on the binding and subcellular distribution of iron regulatory proteins

21 January 2018

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Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

21 January 2018

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Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway

31 March 2020

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Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells

31 March 2020

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Molecular control of vertebrate iron homeostasis by iron regulatory proteins

31 March 2020

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Evidence that the pathway of transferrin receptor mRNA degradation involves an endonucleolytic cleavage within the 3' UTR and does not involve poly(A) tail shortening.

31 March 2020

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Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

31 March 2020

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Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs.

31 March 2020

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