Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes (Q28295404)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7638186 AND SRC:MED&resulttype=core&format=json

22 October 2019

title

Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes (English)

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22 October 2019

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1

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22 October 2019

author name string

E F Petricoin

2

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22 October 2019

J R Ortaldo

3

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22 October 2019

R C Rees

4

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22 October 2019

A C Larner

5

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22 October 2019

J A Johnston

6

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22 October 2019

J J O'Shea

7

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22 October 2019

language of work or name

English

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publication date

1 August 1995

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Proceedings of the National Academy of Sciences of the United States of America

22 October 2019

published in

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22 October 2019

volume

92

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22 October 2019

issue

16

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22 October 2019

page(s)

7307-7311

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JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

22 October 2019

cites work

1 reference

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The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

20 March 2017

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

20 March 2017

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An interleukin-4-induced transcription factor: IL-4 Stat

20 March 2017

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Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes

20 March 2017

1 reference

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Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

20 March 2017

1 reference

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Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation

20 March 2017

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Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

20 March 2017

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Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130

20 March 2017

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Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

20 March 2017

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Identification and purification of human Stat proteins activated in response to interleukin-2

20 March 2017

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Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12

20 March 2017

1 reference

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Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element

20 March 2017

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Purification to homogeneity and partial characterization of cytotoxic lymphocyte maturation factor from human B-lymphoblastoid cells

20 March 2017

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Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells

20 March 2017

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Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

20 March 2017

1 reference

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Requirement of serine phosphorylation for formation of STAT-promoter complexes

20 March 2017

1 reference

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Stat3 and Stat4: members of the family of signal transducers and activators of transcription

20 March 2017

1 reference

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Cytoplasmic activation of GAF, an IFN-gamma-regulated DNA-binding factor

20 March 2017

1 reference

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Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein

20 March 2017

1 reference

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Human cancer cell lines express a negative transcriptional regulator of the interferon regulatory factor family of DNA binding proteins

20 March 2017

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Cytokines that associate with the signal transducer gp130 activate the interferon-induced transcription factor p91 by tyrosine phosphorylation

29 September 2017

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Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts

29 September 2017

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Signaling by the cytokine receptor superfamily: JAKs and STATs.

29 September 2017

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Receptor to nucleus signaling by prolactin and interleukin 2 via activation of latent DNA-binding factors

29 September 2017

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Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2.

29 September 2017

1 reference

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Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes

29 September 2017

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Interleukin-12: a bridge between innate resistance and adaptive immunity with a role in infection and acquired immunodeficiency

29 September 2017

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Signal transduction from the cell surface to the nucleus through the phosphorylation of transcription factors

29 September 2017

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Interleukin-6-induced serine phosphorylation of transcription factor APRF: evidence for a role in interleukin-6 target gene induction

29 September 2017

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Prolactin activates the interferon-regulated p91 transcription factor and the Jak2 kinase by tyrosine phosphorylation

29 September 2017

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Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response.

29 September 2017

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Growth hormone and erythropoietin differentially activate DNA-binding proteins by tyrosine phosphorylation

29 September 2017

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29 September 2017

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29 September 2017

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T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p56lck

29 September 2017

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Characterization of the promoter of the human gene encoding the high-affinity IgG receptor: transcriptional induction by gamma-interferon is mediated through common DNA response elements

29 September 2017

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Interferon gamma rapidly induces in human monocytes a DNA-binding factor that recognizes the gamma response region within the promoter of the gene for the high-affinity Fc gamma receptor

29 September 2017

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Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway

29 September 2017

1 reference

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Interferon-induced nuclear signalling by Jak protein tyrosine kinases

2 June 2018

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Cell surface phenotype of a cloned line of human natural killer cells.

2 June 2018

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T cell antigen receptor engagement stimulates c-raf phosphorylation and induces c-raf-associated kinase activity via a protein kinase C-dependent pathway

2 June 2018

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IL-12 receptor. II. Distribution and regulation of receptor expression

2 June 2018

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The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15.

2 June 2018

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Interferon-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator

27 November 2018

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Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor

27 November 2018

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12 December 2020

Tyrosine phosphorylation of DNA binding proteins by multiple cytokines

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12 December 2020

A common nuclear signal transduction pathway activated by growth factor and cytokine receptors

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12 December 2020

Requirement of Tyrosine Phosphorylation for Rapid Activation of a DNA Binding Factor by IL-4

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12 December 2020

Interleukin-12 induces tyrosine phosphorylation and activation of 44-kD mitogen-activated protein kinase in human T cells

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Identifiers

DOI

10.1073/PNAS.92.16.7307

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7638186 AND SRC:MED&resulttype=core&format=json

22 October 2019

ADS bibcode

1995PNAS...92.7307B

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7638186 AND SRC:MED&resulttype=core&format=json

22 October 2019

PubMed publication ID

7638186

2 references