Presence of tissue transglutaminase in granular endoplasmic reticulum is characteristic of melanized neurons in Parkinson's disease brain (Q28291271)

8

object named as

Benjamin Drukarch

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author name string

Micha M M Wilhelmus

1

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Robin Verhaar

2

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Gerda Andringa

3

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John G J M Bol

4

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Patrick Cras

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Jeroen J M Hoozemans

The role of tissue transglutaminase in 1-methyl-4-phenylpyridinium (MPP )-induced toxicity in differentiated human SH-SY5Y neuroblastoma cells

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language of work or name

English

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publication date

March 2011

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published in

Brain Pathology

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volume

21

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issue

2

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page(s)

130-9

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cites work

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Cellular functions of endoplasmic reticulum chaperones calreticulin, calnexin, and ERp57.

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Staging of brain pathology related to sporadic Parkinson's disease

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Neuropathology of synuclein aggregates

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The release of Hsp70 from A431 carcinoma cells is mediated by secretory-like granules

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Biochemical events in naturally occurring forms of cell death

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Transglutaminase 2: an enigmatic enzyme with diverse functions

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Interaction between tissue transglutaminase and phospholipid vesicles.

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Tissue transglutaminase-catalyzed formation of high-molecular-weight aggregates in vitro is favored with long polyglutamine domains: a possible mechanism contributing to CAG-triplet diseases.

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Tau protein is cross-linked by transglutaminase in P301L tau transgenic mice.

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Activity and distribution of tissue transglutaminase in association with nerve-muscle synapses.

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Lipids associated with tissue transglutaminase.

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Transglutaminase induces protofibril-like amyloid beta-protein assemblies that are protease-resistant and inhibit long-term potentiation

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Proteomic analysis of exosomes secreted by human mesothelioma cells

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Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons

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Activation of the unfolded protein response in Parkinson's disease

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Tissue transglutaminase and the stress response

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Tissue transglutaminase-induced aggregation of alpha-synuclein: Implications for Lewy body formation in Parkinson's disease and dementia with Lewy bodies

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Transglutaminase action imitates Huntington's disease: selective polymerization of Huntingtin containing expanded polyglutamine.

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A novel quality control compartment derived from the endoplasmic reticulum

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Evidence for a role for transglutaminase in Huntington's disease and the potential therapeutic implications

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Cell stress induced by the parkinsonian mimetic, 6-hydroxydopamine, is concurrent with oxidation of the chaperone, ERp57, and aggresome formation

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Effect of tissue transglutaminase on the solubility of proteins containing expanded polyglutamine repeats.

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Proteomic analysis reveals upregulation of calreticulin in murine dopaminergic neuronal cells after treatment with 6-hydroxydopamine

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Transglutaminases: crosslinking enzymes with pleiotropic functions

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Protein targets of oxidative damage in human neurodegenerative diseases with abnormal protein aggregates

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Tissue transglutaminase and apoptosis: sense and antisense transfection studies with human neuroblastoma cells

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Calreticulin, a multi-process calcium-buffering chaperone of the endoplasmic reticulum.

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Transglutaminase-mediated intramolecular cross-linking of membrane-bound alpha-synuclein promotes amyloid formation in Lewy bodies.

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ER chaperones in mammalian development and human diseases

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Elevated transglutaminase-induced bonds in PHF tau in Alzheimer's disease.

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Proteomics identification of acyl-acceptor and acyl-donor substrates for transglutaminase in a human intestinal epithelial cell line. Implications for celiac disease

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Transglutaminase 2: a multi-functional protein in multiple subcellular compartments

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Tissue transglutaminase is a multifunctional BH3-only protein

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ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology

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Mitochondrial complex I deficiency in Parkinson's disease

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Dissecting the mechanisms of tissue transglutaminase-induced cross-linking of alpha-synuclein: implications for the pathogenesis of Parkinson disease

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Tissue transglutaminase modulates alpha-synuclein oligomerization

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Transglutaminase bonds in neurofibrillary tangles and paired helical filament tau early in Alzheimer's disease

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Expanding insights on the involvement of endoplasmic reticulum stress in Parkinson's disease

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Integrin signaling regulates blastocyst adhesion to fibronectin at implantation: intracellular calcium transients and vesicle trafficking in primary trophoblast cells

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Transglutaminases and transglutaminase-catalyzed cross-links colocalize with the pathological lesions in Alzheimer's disease brain

21 January 2018

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Tissue transglutaminase: a novel pharmacological target in preventing toxic protein aggregation in neurodegenerative diseases

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Novel role of transglutaminase 1 in corpora amylacea formation?

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KDEL proteins are found on the surface of NG108-15 cells

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Transglutaminase cross-links in intranuclear inclusions in Huntington disease

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Cell-surface transglutaminase undergoes internalization and lysosomal degradation: an essential role for LRP1.

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