Helicobacter pylori CagA: a new paradigm for bacterial carcinogenesis (Q28287897)

Helicobacter pylori infectious disease

Europe PubMed Central

title

Helicobacter pylori CagA: a new paradigm for bacterial carcinogenesis (English)

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Masanori Hatakeyama

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author name string

Hideaki Higashi

series ordinal

2

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language of work or name

English

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publication date

December 2005

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published in

Cancer Science

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volume

96

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issue

12

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page(s)

835-43

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cites work

Helicobacter pylori infection induces gastric cancer in mongolian gerbils

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Altered states: involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Oncogenic mechanisms of the Helicobacter pylori CagA protein

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Crystal Structure of the Tyrosine Phosphatase SHP-2

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Helicobacter pylori infection and the development of gastric cancer

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

A whole-genome microarray reveals genetic diversity among Helicobacter pylori strains

20 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Cancer burden in the year 2000. The global picture

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

E-cadherin germline mutations in familial gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Analyses of the cag pathogenicity island of Helicobacter pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Risk for gastric cancer in people with CagA positive or CagA negative Helicobacter pylori infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Helicobacter pylori CagA seropositivity and gastric carcinoma risk in a Japanese American population

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Helicobacter pylori CagA protein can be tyrosine phosphorylated in gastric epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Translocation of the Helicobacter pylori CagA protein in gastric epithelial cells by a type IV secretion apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Src is the kinase of the Helicobacter pylori CagA protein in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

c-Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

SHP-2 tyrosine phosphatase as an intracellular target of Helicobacter pylori CagA protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

EPIYA motif is a membrane-targeting signal of Helicobacter pylori virulence factor CagA in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

The CagA protein of Helicobacter pylori is translocated into epithelial cells and binds to SHP-2 in human gastric mucosa

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Conditional gene silencing utilizing the lac repressor reveals a role of SHP-2 in cagA-positive Helicobacter pylori pathogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Integrating the MAP kinase signal into the G1 phase cell cycle machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

SH2 domains from suppressor of cytokine signaling-3 and protein tyrosine phosphatase SHP-2 have similar binding specificities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Attenuation of Helicobacter pylori CagA x SHP-2 signaling by interaction between CagA and C-terminal Src kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

The Helicobacter pylori CagA protein induces cortactin dephosphorylation and actin rearrangement by c-Src inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Helicobacter pylori CagA--a potential bacterial oncoprotein that functionally mimics the mammalian Gab family of adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Grb2 is a key mediator of helicobacter pylori CagA protein activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Helicobacter pylori CagA protein targets the c-Met receptor and enhances the motogenic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Disruption of the epithelial apical-junctional complex by Helicobacter pylori CagA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Activation of beta-catenin by carcinogenic Helicobacter pylori

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Helicobacter pylori CagA protein activates serum response element-driven transcription independently of tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

NF-kappaB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Functional antagonism between Helicobacter pylori CagA and vacuolating toxin VacA in control of the NFAT signaling pathway in gastric epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

A model for gastric cancer epidemiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Association between diversity in the Src homology 2 domain--containing tyrosine phosphatase binding site of Helicobacter pylori CagA protein and gastric atrophy and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Meta-analysis of the relationship between CagA seropositivity and gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Determinants and consequences of different levels of CagA phosphorylation for clinical isolates of Helicobacter pylori.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X

Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1111/J.1349-7006.2005.00130.X