Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL-RANK signaling system (Q28283972)

Europe PubMed Central

title

Role of RANKL in physiological and pathological bone resorption and therapeutics targeting the RANKL-RANK signaling system (English)

0 references

author name string

Sakae Tanaka

1

0 references

Kozo Nakamura

2

0 references

Naoyuki Takahasi

3

0 references

Tatsuo Suda

Bone resorption by osteoclasts

4

0 references

language of work or name

English

0 references

publication date

December 2005

0 references

published in

Immunological Reviews

0 references

volume

208

0 references

page(s)

30-49

0 references

cites work

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Osteonal and hemi-osteonal remodeling: the spatial and temporal framework for signal traffic in adult human bone

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Tumor necrosis factor receptor-associated factor (TRAF) family: adapter proteins that mediate cytokine signaling

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

RANK is essential for osteoclast and lymph node development

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

TRAF7 potentiates MEKK3-induced AP1 and CHOP activation and induces apoptosis

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptor

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-kappaB, a member of the TNFR superfamily

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Distinct molecular mechanism for initiating TRAF6 signalling

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Mitf and Tfe3: members of a b-HLH-ZIP transcription factor family essential for osteoclast development and function

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Microphthalmia-associated transcription factor interacts with PU.1 and c-Fos: determination of their subcellular localization

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Bim: a novel member of the Bcl-2 family that promotes apoptosis

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

A New Mechanism of Bone Destruction in Rheumatoid Arthritis: Synovial Fibroblasts Induce Osteoclastogenesis

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

A mutation in the gene TNFRSF11B encoding osteoprotegerin causes an idiopathic hyperphosphatasia phenotype

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Osteoclast differentiation and activation

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

The biochemistry of apoptosis

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Genetic regulation of osteoclast development and function

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Evolving concepts of rheumatoid arthritis

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X

Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

21 April 2017

1 reference

https://api.crossref.org/works/10.1111/J.0105-2896.2005.00327.X