RhoJ regulates melanoma chemoresistance by suppressing pathways that sense DNA damage (Q28274939)

2

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Rubina Kapadia

3

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Hootan Mehr

4

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Michael A White

5

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Anand K Ganesan

Melanoma genome sequencing reveals frequent PREX2 mutations

6

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language of work or name

English

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publication date

1 November 2012

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published in

Cancer Research

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volume

72

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issue

21

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page(s)

5516-28

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cites work

1 reference

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Chemical genetic screen for AMPKα2 substrates uncovers a network of proteins involved in mitosis

20 March 2017

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Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth

20 March 2017

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The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer

20 March 2017

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Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

20 March 2017

1 reference

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A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer

20 March 2017

1 reference

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MITF: master regulator of melanocyte development and melanoma oncogene

20 March 2017

1 reference

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SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response

20 March 2017

1 reference

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Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin

20 March 2017

1 reference

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Characterization of TCL, a new GTPase of the rho family related to TC10 andCcdc42

20 March 2017

1 reference

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Mechanisms of ATR-mediated checkpoint signalling

20 March 2017

1 reference

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N-terminally truncated BAF57 isoforms contribute to the diversity of SWI/SNF complexes in neurons

20 March 2017

1 reference

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Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

20 March 2017

1 reference

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Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma

7 April 2017

1 reference

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DNA damage-induced cell death: from specific DNA lesions to the DNA damage response and apoptosis

29 September 2017

1 reference

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The role of RhoJ in endothelial cell biology and angiogenesis.

29 September 2017

1 reference

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Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication

29 September 2017

1 reference

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Phosphorylation of SMC1 by ATR is required for desferrioxamine (DFO)-induced apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

Resistance to BRAF Inhibition in Melanomas

29 September 2017

1 reference

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A role for ATF2 in regulating MITF and melanoma development

29 September 2017

1 reference

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Analysis of protein phosphorylation in cisplatin-treated human cells following annexin V-based separation and multi-antibody screening

29 September 2017

1 reference

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Sox proteins in melanocyte development and melanoma

29 September 2017

1 reference

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Gambogic acid triggers DNA damage signaling that induces p53/p21(Waf1/CIP1) activation through the ATR-Chk1 pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

Altered-function p53 missense mutations identified in breast cancers can have subtle effects on transactivation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

Stepping up melanocytes to the challenge of UV exposure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

Pak protein kinases and their role in cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

Integrated genomic and pharmacological approaches to identify synthetic lethal genes as cancer therapeutic targets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

Modeling genomic diversity and tumor dependency in malignant melanoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

The Mre11-Rad50-Nbs1 complex acts both upstream and downstream of ataxia telangiectasia mutated and Rad3-related protein (ATR) to regulate the S-phase checkpoint following UV treatment.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

Synthetic lethal screen identification of chemosensitizer loci in cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

Melanocytes: the new Black

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

Small interfering RNA screens reveal enhanced cisplatin cytotoxicity in tumor cells having both BRCA network and TP53 disruptions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

BLM helicase is activated in BCR/ABL leukemia cells to modulate responses to cisplatin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

Management of cutaneous melanoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

DNA repair pathways in drug resistance in melanoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

Radiation resistance of human melanoma analysed by retroviral insertional mutagenesis reveals a possible role for dopachrome tautomerase.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

RETRACTED: p73alpha regulation by Chk1 in response to DNA damage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

Apoptosis and melanoma chemoresistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

Genome-wide in silico identification of transcriptional regulators controlling the cell cycle in human cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

P21-activated kinase is required for mitotic progression and regulates Plk1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

MEK'ing the most of p53 reactivation therapy in melanoma.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

ATR and H2AX cooperate in maintaining genome stability under replication stress

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

Dacarbazine causes transcriptional up-regulation of interleukin 8 and vascular endothelial growth factor in melanoma cells: a possible escape mechanism from chemotherapy

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3548429

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/22971344

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-12-0775

1 reference

1 reference

1 reference

PubMed publication ID

22971344

1 reference