Inhibition of prostaglandin E2 receptor EP3 mitigates thrombin-induced brain injury (Q28270949)

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2 March 2020

title

Inhibition of prostaglandin E2 receptor EP3 mitigates thrombin-induced brain injury (English)

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2 March 2020

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8

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2 March 2020

author name string

Xiaoning Han

1

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2 March 2020

Xi Lan

2

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2 March 2020

Qiang Li

3

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2 March 2020

Yufeng Gao

4

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2 March 2020

Wei Zhu

5

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2 March 2020

Tian Cheng

6

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2 March 2020

Takayuki Maruyama

7

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2 March 2020

language of work or name

English

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publication date

2 October 2015

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Journal of Cerebral Blood Flow & Metabolism

2 March 2020

published in

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2 March 2020

volume

36

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2 March 2020

issue

6

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2 March 2020

page(s)

1059-1074

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Toxic role of prostaglandin E2 receptor EP1 after intracerebral hemorrhage in mice

2 March 2020

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PGE2 receptor agonist misoprostol protects brain against intracerebral hemorrhage in mice

20 March 2017

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(-)-Epicatechin protects hemorrhagic brain via synergistic Nrf2 pathways

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Expression and cellular localization of cyclooxygenases and prostaglandin E synthases in the hemorrhagic brain

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Involvement of PGE2 and PGDH but not COX-2 in thrombin-induced cortical neuron apoptosis

20 March 2017

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20 March 2017

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Increased activity of Rho kinase contributes to hemoglobin-induced early disruption of the blood-brain barrier in vivo after the occurrence of intracerebral hemorrhage

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An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration

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Microsomal prostaglandin E synthase-1 contributes to ischaemic excitotoxicity through prostaglandin E2 EP3 receptors.

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Blood-brain barrier breakdown and repair by Src after thrombin-induced injury

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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PDGFR-α inhibition preserves blood-brain barrier after intracerebral hemorrhage.

29 September 2017

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Effects of thrombin on neurogenesis after intracerebral hemorrhage

2 June 2018

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Inhibition of prostaglandin E2 EP3 receptors improves stroke injury via anti-inflammatory and anti-apoptotic mechanisms.

2 June 2018

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Involvement of microglial RhoA/Rho-kinase pathway activation in the dopaminergic neuron death. Role of angiotensin via angiotensin type 1 receptors

21 January 2018

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PKC-delta/c-Src-mediated EGF receptor transactivation regulates thrombin-induced COX-2 expression and PGE(2) production in rat vascular smooth muscle cells

21 January 2018

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Relative importance of proteinase-activated receptor-1 versus matrix metalloproteinases in intracerebral hemorrhage-mediated neurotoxicity in mice

21 January 2018

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Prostaglandin E receptor subtype EP3 in conjunctival epithelium regulates late-phase reaction of experimental allergic conjunctivitis

21 January 2018

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Combination of thrombin and matrix metalloproteinase-9 exacerbates neurotoxicity in cell culture and intracerebral hemorrhage in mice.

21 January 2018

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Thrombin-induced delayed injury involves multiple and distinct signaling pathways in the cerebral cortex and the striatum in organotypic slice cultures

21 January 2018

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Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia.

21 January 2018

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Inhibition of the Rho/ROCK pathway prevents neuronal degeneration in vitro and in vivo following methylmercury exposure

21 January 2018

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Microglial expression of prostaglandin EP3 receptor in excitotoxic lesions in the rat striatum

21 January 2018

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Hemoglobin affects lipid peroxidation and prostaglandin E2 formation in rat corticocerebral tissues in vitro

21 January 2018

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21 January 2018

Identifiers

DOI

10.1177/0271678X15606462

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26661165 AND SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

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2 March 2020

PubMed publication ID

26661165

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26661165 AND SRC:MED&resulttype=core&format=json