Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels (Q28265776)

Glutamate-cysteine ligase, modifier subunit

GOA release 2020-03-11

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GOA release 2020-03-11

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Ying Chen

1

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Howard G Shertzer

2

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Scott N Schneider

3

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Daniel W Nebert

4

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Timothy P Dalton

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

7 October 2005

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published in

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volume

280

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issue

40

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page(s)

33766-74

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https://api.crossref.org/works/10.1074/JBC.M504604200

Genetically altered mice to evaluate glutathione homeostasis in health and disease

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Reactive intermediates and the dynamics of glutathione transferases

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The changing faces of glutathione, a cellular protagonist

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1 reference

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The biochemistry and physiology of S-nitrosothiols

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S-nitrosothiols signal the ventilatory response to hypoxia

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Modulation of glutamate receptor functions by glutathione

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1 reference

https://api.crossref.org/works/10.1074/JBC.M504604200

Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response

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1 reference

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Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous

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1 reference

https://api.crossref.org/works/10.1074/JBC.M504604200

Glutathione synthesis is essential for mouse development but not for cell growth in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M504604200

Drosophila melanogaster glutamate-cysteine ligase activity is regulated by a modifier subunit with a mechanism of action similar to that of the mammalian form

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M504604200

Expression and characterization of human glutamate-cysteine ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M504604200

In Situ Measurement of Glutamate Concentrations in the Periportal, Intermediate, and Pericentral Zones of Rat Liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M504604200

Polymorphism in the 5'-flanking region of human glutamate-cysteine ligase modifier subunit gene is associated with myocardial infarction

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1 reference

https://api.crossref.org/works/10.1074/JBC.M504604200

Polymorphism in glutamate-cysteine ligase modifier subunit gene is associated with impairment of nitric oxide-mediated coronary vasomotor function

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1 reference

https://api.crossref.org/works/10.1074/JBC.M504604200

Association of polymorphism in glutamate-cysteine ligase catalytic subunit gene with coronary vasomotor dysfunction and myocardial infarction

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1 reference

https://api.crossref.org/works/10.1074/JBC.M504604200

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M504604200

Cell cycle-dependent regulation of cellular ATP concentration, and depolymerization of the interphase microtubular network induced by elevated cellular ATP concentration in whole fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M504604200

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

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1 reference

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A novel method for measurement of submembrane ATP concentration

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1 reference

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Blockade of Myocardial ATP-sensitive Potassium Channels by Ketamine

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1 reference

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Variable regulation of glutamate cysteine ligase subunit proteins affects glutathione biosynthesis in response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M504604200

Increased gamma-glutamylcysteine synthetase and gamma-glutamyl transpeptidase activities enhance resistance of rat lung epithelial L2 cells to quinone toxicity

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1 reference

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Differential regulation of γ-glutamylcysteine synthetase heavy and light subunit gene expression

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1 reference

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Regulation of gamma-glutamylcysteine synthetase by protein phosphorylation

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1 reference

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Glutathione, iron and Parkinson's disease

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1 reference

https://api.crossref.org/works/10.1074/JBC.M504604200

Mitochondrial impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells: relevance to Parkinson's disease

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1 reference

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Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease

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Identifiers

DOI

10.1074/JBC.M504604200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

16081425

1 reference

Consolidated OpenCitations Corpus – April 2017