The PC12 cell as model for neurosecretion (Q28257458)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18005394 AND SRC:MED&resulttype=core&format=json

26 December 2019

review article

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title

The PC12 cell as model for neurosecretion (English)

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26 December 2019

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1

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26 December 2019

author name string

A G Ewing

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18005394 AND SRC:MED&resulttype=core&format=json

26 December 2019

language of work or name

English

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publication date

15 November 2007

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26 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18005394 AND SRC:MED&resulttype=core&format=json

26 December 2019

volume

192

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26 December 2019

issue

2

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26 December 2019

page(s)

273-285

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describes a project that uses

26 December 2019

PC12

0 references

cites work

The synaptic vesicle cycle

1 reference

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Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport

20 March 2017

1 reference

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Temporally resolved catecholamine spikes correspond to single vesicle release from individual chromaffin cells

20 March 2017

1 reference

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Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

20 March 2017

1 reference

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Lithium ions Up-regulate mRNAs encoding dense-core vesicle proteins in nerve growth factor-differentiated PC12 cells

20 March 2017

1 reference

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Inositol trisphosphate, a novel second messenger in cellular signal transduction

20 March 2017

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Neonatal exposure to brominated flame retardant BDE-47 reduces long-term potentiation and postsynaptic protein levels in mouse hippocampus

7 April 2017

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The last decade of solvent research in animal models of abuse: mechanistic and behavioral studies.

29 September 2017

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Neurochemical targets and behavioral effects of organohalogen compounds: an update

29 September 2017

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Targeting exocytosis: ins and outs of the modulation of quantal dopamine release

29 September 2017

1 reference

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Stable gene silencing of synaptotagmin I in rat PC12 cells inhibits Ca2 -evoked release of catecholamine.

29 September 2017

1 reference

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Molecular mechanisms involved in the toxic effects of polychlorinated biphenyls (PCBs) and brominated flame retardants (BFRs).

29 September 2017

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Calcium-dependent regulation of exocytosis

29 September 2017

1 reference

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SCAMP2 interacts with Arf6 and phospholipase D1 and links their function to exocytotic fusion pore formation in PC12 cells

29 September 2017

1 reference

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Correlation between vesicle quantal size and fusion pore release in chromaffin cell exocytosis

29 September 2017

1 reference

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Presynaptic disruption of transmitter release by lead

29 September 2017

1 reference

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Transmembrane segments of syntaxin line the fusion pore of Ca2 -triggered exocytosis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Dopamine neurons release transmitter via a flickering fusion pore

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Convergent effects of lithium and valproate on the expression of proteins associated with large dense core vesicles in NGF-differentiated PC12 cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Intracellular patch electrochemistry: regulation of cytosolic catecholamines in chromaffin cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Secretory granule exocytosis

29 September 2017

1 reference

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Artificial cells: unique insights into exocytosis using liposomes and lipid nanotubes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Ca(2 ) -independent vesicular catecholamine release in PC12 cells by nanomolar concentrations of Pb(2 ).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Synaptotagmin I is a molecular target for lead

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

VMAT-Mediated changes in quantal size and vesicular volume.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

L-3,4-dihydroxyphenylalanine increases the quantal size of exocytotic dopamine release in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine adrenal chromaffin cells

29 September 2017

1 reference

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Influence of heavy metals on synaptic transmission: a review

29 September 2017

1 reference

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Use of isolated chromaffin cells to study basic release mechanisms

29 September 2017

1 reference

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Control of exocytosis from adrenal chromaffin cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Nicotinic receptor-mediated catecholamine secretion from individual chromaffin cells. Chemical evidence for exocytosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

The adrenal medulla: A model for studies of hormonal and neuronal storage and release mechanisms

29 September 2017

1 reference

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Storage and release of acetylcholine by a clonal cell line

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Signaling pathways involved in Ca2 - and Pb2 -induced vesicular catecholamine release from rat PC12 cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Vesicular catecholamine release from rat PC12 cells on acute and subchronic exposure to polychlorinated biphenyls.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Toluene-induced, Ca(2 )-dependent vesicular catecholamine release in rat PC12 cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

The effect of transfection with Botulinum neurotoxin C1 light chain on exocytosis measured in cell populations and by single-cell amperometry in PC12 cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Quantitative measurements of released amines from individual exocytosis events

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Vesicular quantal size measured by amperometry at chromaffin, mast, pheochromocytoma, and pancreatic beta-cells.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Release of secretory products during transient vesicle fusion.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Metal interactions with voltage- and receptor-activated ion channels.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Direct in vivo monitoring of dopamine released from two striatal compartments in the rat.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Delay in vesicle fusion revealed by electrochemical monitoring of single secretory events in adrenal chromaffin cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Monitoring of transmitter metabolites by voltammetry in cerebrospinal fluid following neural pathway stimulation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Release, storage and uptake of catecholamines by a clonal cell line of nerve growth factor (NGF) responsive pheochromocytoma cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Patch amperometry: high-resolution measurements of single-vesicle fusion and release

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Lithium enhances secretion from large dense-core vesicles in nerve growth factor-differentiated PC12 cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Loaded dopamine is preferentially stored in the halo portion of PC12 cell dense core vesicles

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

The Effects of Vesicular Volume on Secretion through the Fusion Pore in Exocytotic Release from PC12 Cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Secretory vesicles membrane area is regulated in tandem with quantal size in chromaffin cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Different domains of synaptotagmin control the choice between kiss-and-run and full fusion.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Toluene inhibits voltage-sensitive calcium channels expressed in pheochromocytoma cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Hypoxia potentiates exocytosis and Ca2 channels in PC12 cells via increased amyloid beta peptide formation and reactive oxygen species generation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Prion protein fragment 106-126 potentiates catecholamine secretion from PC-12 cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Synaptotagmin modulation of fusion pore kinetics in regulated exocytosis of dense-core vesicles

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Amyloid beta peptides mediate hypoxic augmentation of Ca(2 ) channels.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Quantitative and statistical analysis of the shape of amperometric spikes recorded from two populations of cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Hypoxic enhancement of quantal catecholamine secretion. Evidence for the involvement of amyloid beta-peptides.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Chronic hypoxia enhances the secretory response of rat phaeochromocytoma cells to acute hypoxia.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Hypoxia evokes catecholamine secretion from rat pheochromocytoma PC-12 cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

D2-Like dopamine autoreceptor activation reduces quantal size in PC12 cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

The exocytotic event in chromaffin cells revealed by patch amperometry

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

Electrochemical monitoring of individual exocytotic events from the varicosities of differentiated PC12 cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2663028

The latency of exocytosis varies with the mechanism of stimulated release in PC12 cells

27 November 2018

1 reference

12 December 2020

Distinct mechanisms of neurotransmitter release from PC 12 cells exposed to lead

1 reference

12 December 2020

Spatio-temporal resolution of exocytosis from individual cells

1 reference

12 December 2020

Effects of Cd2 , Pb2 and CH3Hg on high voltage-activated calcium currents in pheochromocytoma (PC12) cells: potency, reversibility, interactions with extracellular Ca2 and mechanisms of block

1 reference

12 December 2020

Acute toluene induces biphasic changes in rat spontaneous locomotor activity which are blocked by remoxipride

1 reference

12 December 2020

Ion selectivities of the Ca(2 ) sensors for exocytosis in rat phaeochromocytoma cells

1 reference

12 December 2020

Determining Sizes and Distribution of Sizes of Spherical Bodies such as Chromaffin Granules in Tissue Sections

1 reference

12 December 2020

Sodium and calcium fluxes in a clonal nerve cell line

1 reference

12 December 2020

The modulation of neurotransmitter synthesis by steroid hormones and insulin

1 reference

12 December 2020

In vivo electrochemical detection of catechols in the neostriatum of anaesthetized rats: dopamine or DOPAC?

1 reference

12 December 2020

Evaluation of amphetamine-induced in vivo electrochemical response

1 reference

12 December 2020

Glucocorticoids increase catecholamine synthesis and storage in PC12 pheochromocytoma cell cultures

1 reference

12 December 2020

Amperometric monitoring of stimulated catecholamine release from rat pheochromocytoma (PC12) cells at the zeptomole level

1 reference

12 December 2020

Lead neurotoxicity: from exposure to molecular effects

1 reference

12 December 2020

Synaptotagmin-Ca2 triggers two sequential steps in regulated exocytosis in rat PC12 cells: fusion pore opening and fusion pore dilation

1 reference

12 December 2020

Alpha-synuclein overexpression increases cytosolic catecholamine concentration

1 reference

12 December 2020

Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis

1 reference

12 December 2020

Enhancement of the dense-core vesicle secretory cycle by glucocorticoid differentiation of PC12 cells: characteristics of rapid exocytosis and endocytosis

1 reference

12 December 2020

Heterogeneity of catecholamine-containing vesicles in PC12 cells

1 reference

12 December 2020

Voltammetric and pharmacological characterization of dopamine release from single exocytotic events at rat pheochromocytoma (PC12) cells

1 reference

12 December 2020

10.1111/J.1748-1716.2007.01805.X

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18005394 AND SRC:MED&resulttype=core&format=json

26 December 2019

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18005394 AND SRC:MED&resulttype=core&format=json

26 December 2019

PubMed publication ID

18005394

2 references