MeCP2: the chromatin connection and beyond (Q28256925)

Biochemistry and Cell Biology

Europe PubMed Central

title

MeCP2: the chromatin connection and beyond (English)

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author name string

Jordanka Zlatanova

series ordinal

1

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language of work or name

English

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publication date

June 2005

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published in

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volume

83

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issue

3

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page(s)

251-62

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cites work

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

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Real-time quantitative PCR as a routine method for screening large rearrangements in Rett syndrome: Report of one case of MECP2 deletion and one case of MECP2 duplication.

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Methyl-CpG-binding proteins. Targeting specific gene repression.

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Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer.

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The impact of MECP2 mutations in the expression patterns of Rett syndrome patients.

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CpG-rich islands and the function of DNA methylation

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Methylation-induced repression--belts, braces, and chromatin

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Chromosomal regulation by MeCP2: structural and enzymatic considerations

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A WW domain binding region in methyl-CpG-binding protein MeCP2: impact on Rett syndrome

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DNA methylation and chromatin structure: the puzzling CpG islands

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A novel protein, Xenopus p20, influences the stability of MeCP2 through direct interaction.

21 January 2018

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Expression of the methyl-CpG-binding protein MeCP2 in rat brain. An ontogenetic study

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Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

21 January 2018

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Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2

21 January 2018

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Expression of MeCP2 in olfactory receptor neurons is developmentally regulated and occurs before synaptogenesis

21 January 2018

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Gene expression profiling in postmortem Rett Syndrome brain: differential gene expression and patient classification.

21 January 2018

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Mild overexpression of MeCP2 causes a progressive neurological disorder in mice.

21 January 2018

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A complex pattern of evolutionary conservation and alternative polyadenylation within the long 3"-untranslated region of the methyl-CpG-binding protein 2 gene (MeCP2) suggests a regulatory role in gene expression

21 January 2018

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Characterization of the human STAT5A and STAT5B promoters: evidence of a positive and negative mechanism of transcriptional regulation.

21 January 2018

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Purification of CpG islands using a methylated DNA binding column

21 January 2018

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Suppression of MeCP2beta expression inhibits neurite extension in PC12 cells

21 January 2018

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Methylation-dependent silencing at the H19 imprinting control region by MeCP2

21 January 2018

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Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation

21 January 2018

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CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future

21 January 2018

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Allele-specific histone lysine methylation marks regulatory regions at imprinted mouse genes

21 January 2018

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The affinity of different MBD proteins for a specific methylated locus depends on their intrinsic binding properties

21 January 2018

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The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation

21 January 2018

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Chromatin compaction by human MeCP2. Assembly of novel secondary chromatin structures in the absence of DNA methylation

21 January 2018

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Rett syndrome: of girls and mice--lessons for regression in autism

21 January 2018

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DNA methylation is linked to deacetylation of histone H3, but not H4, on the imprinted genes Snrpn and U2af1-rs1.

21 January 2018

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A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

21 January 2018

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Identification and characterization of a family of mammalian methyl-CpG binding proteins

21 January 2018

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Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

21 January 2018

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MeCP2 driven transcriptional repression in vitro: selectivity for methylated DNA, action at a distance and contacts with the basal transcription machinery

21 January 2018

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MECP2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions

21 January 2018

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Molecular biology. MeCP2 repression goes nonglobal

21 January 2018

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MeCP2 behaves as an elongated monomer that does not stably associate with the Sin3a chromatin remodeling complex

21 January 2018

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DNA binding of methyl-CpG-binding protein MeCP2 in human MCF7 cells

21 January 2018

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Heterogeneity in the modification and involvement of chromatin components of the CpG island of the silenced human CDH1 gene in cancer cells

21 January 2018

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DNA methylation and Rett syndrome

21 January 2018

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The major form of MeCP2 has a novel N-terminus generated by alternative splicing

21 January 2018

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Methyl-CpG-binding protein MeCP2 represses Sp1-activated transcription of the human leukosialin gene when the promoter is methylated

21 January 2018

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Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA

21 January 2018

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Methylation-mediated proviral silencing is associated with MeCP2 recruitment and localized histone H3 deacetylation

21 January 2018

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Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice

21 January 2018

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Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia

21 January 2018

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Regional methylation of the 5' end CpG island of BRCA1 is associated with reduced gene expression in human somatic cells

21 January 2018

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Role of de novo DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma

21 January 2018

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DNA Methylation-Related Chromatin Remodeling in Activity-Dependent Bdnf Gene Regulation

21 January 2018

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Temporal and regional differences in the olfactory proteome as a consequence of MeCP2 deficiency

21 January 2018

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The transcriptional repressor Mecp2 regulates terminal neuronal differentiation

21 January 2018

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Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA

21 January 2018

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Mutations and polymorphisms in the human methyl CpG-binding protein MECP2

21 January 2018

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A previously unidentified MECP2 open reading frame defines a new protein isoform relevant to Rett syndrome

21 January 2018

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Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome

21 January 2018

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DNA methylation specifies chromosomal localization of MeCP2.

21 January 2018

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MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

21 January 2018

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

21 January 2018

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Rett syndrome: a prototypical neurodevelopmental disorder

21 January 2018

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Altered chromatin structure associated with methylation-induced gene silencing in cancer cells: correlation of accessibility, methylation, MeCP2 binding and acetylation

21 January 2018

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Solution structure of the methyl-CpG-binding domain of the methylation-dependent transcriptional repressor MBD1

21 January 2018

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Solution structure of the methyl-CpG binding domain of human MBD1 in complex with methylated DNA

21 January 2018

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Comparative sequence analysis of the MECP2-locus in human and mouse reveals new transcribed regions

21 January 2018

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Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation

21 January 2018

1 reference

MECP2 structural and 3'-UTR variants in schizophrenia, autism and other psychiatric diseases: a possible association with autism

21 January 2018

1 reference

A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by notch in Xenopus embryos

21 January 2018

1 reference

Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells.

21 January 2018

1 reference

Gene expression patterns vary in clonal cell cultures from Rett syndrome females with eight different MECP2 mutations

21 January 2018

1 reference

Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain

21 January 2018

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Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2).

21 January 2018

1 reference

Methyl CpG-binding proteins and transcriptional repression

21 January 2018

1 reference

Methyl CpG binding proteins: coupling chromatin architecture to gene regulation

21 January 2018

1 reference

The solution structure of the domain from MeCP2 that binds to methylated DNA

21 January 2018

1 reference

Chicken MAR-Binding Protein ARBP Is Homologous to Rat Methyl-CpG-Binding Protein MeCP2

21 January 2018

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X-chromosome inactivation patterns are unbalanced and affect the phenotypic outcome in a mouse model of rett syndrome

21 January 2018

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Functional consequences of Rett syndrome mutations on human MeCP2.

21 January 2018

1 reference

Postnatal Neurodevelopmental Disorders: Meeting at the Synapse?

21 January 2018

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