Crystal structure of human thimet oligopeptidase provides insight into substrate recognition, regulation, and localization (Q28248182)

https://api.crossref.org/works/10.1074/JBC.M400795200

Evolutionary families of metallopeptidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Soluble metalloendopeptidases and neuroendocrine signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Human thimet oligopeptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Synaptosomal membrane-bound form of endopeptidase-24.15 generates Leu-enkephalin from dynorphin1-8, alpha- and beta-neoendorphin, and Met-enkephalin from Met-enkephalin-Arg6-Gly7-Leu8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Soluble metalloendopeptidase from rat brain: action on enkephalin-containing peptides and other bioactive peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Immunocytochemical localization of endopeptidase 24.15 in rat brain

21 January 2018

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https://api.crossref.org/works/10.1074/JBC.M400795200

Molecular cloning and primary structure of rat testes metalloendopeptidase EC 3.4.24.15

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Endopeptidase EC 3.4.24.15 Presence in the Rat Median Eminence and Hypophysial Portal Blood and its Modulation of the Luteinizing Hormone Surge

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Characterization of an endooligopeptidase A-like protein in PC12 cells: activity modulation by cAMP but not by basic fibroblast growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Secretion of metalloendopeptidase 24.15 (EC 3.4.24.15)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Comparative fine structural distribution of endopeptidase 24.15 (EC3.4.24.15) and 24.16 (EC3.4.24.16) in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Confocal microscopy reveals thimet oligopeptidase (EC 3.4.24.15) and neurolysin (EC 3.4.24.16) in the classical secretory pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Differential subcellular distribution of neurolysin (EC 3.4.24.16) and thimet oligopeptidase (EC 3.4.24.15) in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

A soluble metalloendopeptidase from rat brain. Purification of the enzyme and determination of specificity with synthetic and natural peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

The association of metalloendopeptidase EC 3.4.24.15 at the extracellular surface of the AtT-20 cell plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Immunolocalization of thimet oligopeptidase in chicken embryonic fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Purification of the main somatostatin-degrading proteases from rat and pig brains, their action on other neuropeptides, and their identification as endopeptidases 24.15 and 24.16

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Chicken liver Pz-peptidase, a thiol-dependent metallo-endopeptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Contribution of endopeptidase 3.4.24.15 to central neurotensin inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Endopeptidase 24.15 from rat testes. Isolation of the enzyme and its specificity toward synthetic and natural peptides, including enkephalin-containing peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Peptidases that Degrade Gonadotropin‐Releasing Hormone: Influence on LH Secretion in the Ewe

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Major histocompatibility complex class I-presented antigenic peptides are degraded in cytosolic extracts primarily by thimet oligopeptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Regulation of cell-surface major histocompatibility complex class I expression by the endopeptidase EC3.4.24.15 (thimet oligopeptidase).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Thimet oligopeptidase cleaves the full-length Alzheimer amyloid precursor protein at a beta-secretase cleavage site in COS cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Metalloendopeptidase EC 3.4.24.15 is necessary for Alzheimer's amyloid-beta peptide degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Expression of the thimet oligopeptidase gene is regulated by positively and negatively acting elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Thimet oligopeptidase expression is differentially regulated in neuroendocrine and spermatid cell lines by transcription factor binding to SRY (sex-determining region Y), CAAT and CREB (cAMP-response-element-binding protein) promoter consensus seque

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Regulators of the neuropeptide-degrading enzyme, EC 3.4.24.15 (thimet oligopeptidase), in cerebrospinal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Involvement of surface cysteines in activity and multimer formation of thimet oligopeptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

The neuropeptide processing enzyme EC 3.4.24.15 is modulated by protein kinase A phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Free ATP inhibits thimet oligopeptidase (EC 3.4.24.15) activity, induces autophosphorylation in vitro, and controls oligopeptide degradation in macrophage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Molecular Cloning and Expression of Rat Brain Endopeptidase 3.4.24.16

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Neuropeptide specificity and inhibition of recombinant isoforms of the endopeptidase 3.4.24.16 family: comparison with the related recombinant endopeptidase 3.4.24.15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Phosphorus‐containing peptides as mixed inhibitors of endopeptidase 3.4.24.15 and 3.4.24.16: effect on neurotensin degradation in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Structural features that make oligopeptides susceptible substrates for hydrolysis by recombinant thimet oligopeptidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Selective neurotensin-derived internally quenched fluorogenic substrates for neurolysin (EC 3.4.24.16): comparison with thimet oligopeptidase (EC 3.4.24.15) and neprilysin (EC 3.4.24.11).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Substrate specificity characterization of recombinant metallo oligo-peptidases thimet oligopeptidase and neurolysin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Structure of neurolysin reveals a deep channel that limits substrate access

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Mapping sequence differences between thimet oligopeptidase and neurolysin implicates key residues in substrate recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

[13] Practical cryocrystallography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Crystal structure of the human angiotensin-converting enzyme-lisinopril complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Crystal structure of a novel carboxypeptidase from the hyperthermophilic archaeon Pyrococcus furiosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Crystallographic study of the binding of dipeptide inhibitors to thermolysin: implications for the mechanism of catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Defining solution conformations of small linear peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Structure of astacin with a transition-state analogue inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Cleavage of precursors by the mitochondrial processing peptidase requires a compatible mature protein or an intermediate octapeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Two mitochondrial matrix proteases act sequentially in the processing of mammalian matrix enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

A structure-based site-directed mutagenesis study on the neurolysin (EC 3.4.24.16) and thimet oligopeptidase (EC 3.4.24.15) catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M400795200