Pharmacogenetics in inflammatory bowel disease (Q28246002)

inflammatory bowel diseases

Europe PubMed Central

title

Pharmacogenetics in inflammatory bowel disease (English)

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main subject

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2

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Séverine Vermeire

series ordinal

4

object named as

Severine Vermeire

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Robert F Vlietinck

series ordinal

3

object named as

Robert Vlietinck

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Marie Pierik

series ordinal

1

object named as

Marie Pierik

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language of work or name

English

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publication date

21 June 2006

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published in

World Journal of Gastroenterology

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volume

12

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issue

23

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page(s)

3657-67

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cites work

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Polyglutamation of methotrexate with common polymorphisms in reduced folate carrier, aminoimidazole carboxamide ribonucleotide transformylase, and thymidylate synthase are associated with methotrexate effects in rheumatoid arthritis

20 March 2017

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Pharmacogenetics of thiopurine S-methyltransferase and thiopurine therapy

20 March 2017

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6-thioguanine can cause serious liver injury in inflammatory bowel disease patients

20 March 2017

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Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

20 March 2017

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Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease

20 March 2017

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Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine, or balsalazide

20 March 2017

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

20 March 2017

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

20 March 2017

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Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease

20 March 2017

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Rational dosing of azathioprine and 6-mercaptopurine

20 March 2017

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Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

20 March 2017

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A comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease. North American Crohn's Study Group Investigators

20 March 2017

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Azathioprine or 6-mercaptopurine for inducing remission of Crohn's disease

20 March 2017

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A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase

20 March 2017

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Nomenclature for N-acetyltransferases

20 March 2017

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A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

20 March 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity

20 March 2017

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Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype

20 March 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease

20 March 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

PEDSTATS: descriptive statistics, graphics and quality assessment for gene mapping data

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Low-dose methotrexate: a mainstay in the treatment of rheumatoid arthritis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Infliximab induces apoptosis of monocytes and T lymphocytes in a human-mouse chimeric model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Thiopurine methyltransferase: should it be measured before commencing thiopurine drug therapy?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Analytic aspects of monitoring therapy with thiopurine medications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Optimizing anti-TNF treatment in inflammatory bowel disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Management of inflammatory bowel disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Predictors of oral mucositis in patients receiving hematopoietic cell transplants for chronic myelogenous leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

MDR1 Ala893 polymorphism is associated with inflammatory bowel disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Glucocorticoid resistance in inflammatory bowel disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Slow acetylator genotypes as a possible risk factor for infectious mononucleosis-like syndrome induced by salazosulfapyridine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4 T lymphocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Pharmacogenomics--drug disposition, drug targets, and side effects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Crohn's disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Safe treatment of thiopurine S-methyltransferase deficient Crohn's disease patients with azathioprine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

N-acetyltransferase 1 and 2 genotypes do not predict response or toxicity to treatment with mesalamine and sulfasalazine in patients with ulcerative colitis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

A review of activity indices and efficacy endpoints for clinical trials of medical therapy in adults with Crohn's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Genetic polymorphism of thiopurine S-methyltransferase: molecular mechanisms and clinical importance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Azathioprine for maintaining remission of Crohn's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Genetic polymorphism of thiopurine methyltransferase and its clinical relevance for childhood acute lymphoblastic leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Infliximab for the treatment of fistulas in patients with Crohn's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Review article: refractory distal colitis -- explanations and options

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 years of experience

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Frequency of glucocorticoid resistance and dependency in Crohn's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

N-acetylation pharmacogenetics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

The clinical pharmacology of 6-mercaptopurine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Functional characterization of nucleotide polymorphisms in the coding region of N-acetyltransferase 1.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Molecular mechanisms of genetic polymorphisms of drug metabolism

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

A prospective randomized observer-blind 2-year trial of azathioprine monotherapy versus azathioprine and olsalazine for the maintenance of remission of steroid-dependent ulcerative colitis

2 June 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Identification of two novel sequence variants affecting thiopurine methyltransferase enzyme activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Isolation of a human thiopurine S-methyltransferase (TPMT) complementary DNA with a single nucleotide transition A719G (TPMT*3C) and its association with loss of TPMT protein and catalytic activity in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: implications for therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Some cases demonstrating the clinical usefulness of therapeutic drug monitoring in thiopurine-treated inflammatory bowel disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Thiopurine methyltransferase activity and the use of azathioprine in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase).

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Pharmacological Monitoring of Azathioprine Therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Relevance of thiopurine methyltransferase activity in inflammatory bowel disease patients maintained on low-dose azathioprine

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Human thiopurine S-methyltransferase activity in uremia and after renal transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population.

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Cost-effectiveness of thiopurine methyltransferase genotype screening in patients about to commence azathioprine therapy for treatment of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Small bowel malignancy at diagnosis of coeliac disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Novel human N-acetyltransferase 2 alleles that differ in mechanism for slow acetylator phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Correlation between genotype and phenotype of the human arylamine N-acetyltransferase type 1 (NAT1).

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Sulphasalazine-induced leucopenia in a patient with renal dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Pharmacogenetics of methotrexate: toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

MDR1 mRNA expressions in peripheral blood mononuclear cells of patients with ulcerative colitis in relation to glucocorticoid administration

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

NOD2/CARD15 does not influence response to infliximab in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Tumour necrosis factor-alpha receptor 1 and 2 polymorphisms in inflammatory bowel disease and their association with response to infliximab

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

ANCA pattern and LTA haplotype relationship to clinical responses to anti-TNF antibody treatment in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Polymorphisms in apoptosis genes predict response to infliximab therapy in luminal and fistulizing Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Association between polymorphism in IgG Fc receptor IIIa coding gene and biological response to infliximab in Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Response to infliximab treatment in Crohn's disease is not associated with mutations in the CARD15 (NOD2) gene: an analysis in 534 patients from two multicenter, prospective GCP-level trials

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Pharmacogenetic investigation of the TNF/TNF-receptor system in patients with chronic active Crohn's disease treated with infliximab

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3748/WJG.V12.I23.3657

ITPA genotyping test does not improve detection of Crohn's disease patients at risk of azathioprine/6-mercaptopurine induced myelosuppression

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Early nodular hyperplasia of the liver occurring with inflammatory bowel diseases in association with thioguanine therapy

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Clinical use and practical application of TPMT enzyme and 6-mercaptopurine metabolite monitoring in IBD.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

The C677T mutation in the methylenetetrahydrofolate reductase gene: a genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: a forty-eight week, multicenter, randomized, double-blind, placebo-controlled study

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

A novel single-nucleotide polymorphism in the 3'-untranslated region of the human dihydrofolate reductase gene with enhanced expression

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Variants of N-acetyltransferase NAT1 and a case-control study of colorectal adenomas.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

Ethnic distribution of slow acetylator mutations in the polymorphic N-acetyltransferase (NAT2) gene

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4087457

The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study

27 November 2018

1 reference

12 December 2020

Shortcoming in the diagnosis of TPMT deficiency in a patient with Crohn's disease using phenotyping only

1 reference

12 December 2020

Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene

1 reference

12 December 2020

A positive response to infliximab in Crohn disease: association with a higher systemic inflammation before treatment but not with -308 TNF gene polymorphism

1 reference

12 December 2020

Pharmacogenetics-based therapeutic recommendations — ready for clinical practice?

1 reference

12 December 2020

Sero-reactivity to microbial components in Crohn's disease is associated with disease severity and progression, but not NOD2/CARD15 genotype

1 reference

12 December 2020

High multidrug resistance (P-glycoprotein 170) expression in inflammatory bowel disease patients who fail medical therapy

1 reference

12 December 2020

Screening of thiopurine S-methyltransferase mutations by horizontal conformation-sensitive gel electrophoresis

1 reference

12 December 2020

Expression of glucocorticoid receptor beta in lymphocytes of patients with glucocorticoid-resistant ulcerative colitis

1 reference

12 December 2020

MTHFR gene polymorphism and severe toxicity during adjuvant treatment of early breast cancer with cyclophosphamide, methotrexate, and fluorouracil (CMF)

1 reference

12 December 2020

Primary cortisol resistance accompanied by a reduction in glucocorticoid receptors in two members of the same family

1 reference

12 December 2020

6-Mercaptopurine in the management of inflammatory bowel disease: short- and long-term toxicity

1 reference

12 December 2020

The importance of methylthio-IMP for methylmercaptopurine ribonucleoside (Me-MPR) cytotoxicity in Molt F4 human malignant T-lymphoblasts

1 reference

12 December 2020

Steroid dependency in Crohn's disease

1 reference

12 December 2020

Methylation of mercaptopurine, thioguanine, and their nucleotide metabolites by heterologously expressed human thiopurine S-methyltransferase

1 reference

12 December 2020

Intraindividual variability in red blood cell thiopurine methyltransferase activity

1 reference

12 December 2020

Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis

1 reference

12 December 2020