Regulation of eukaryotic phosphatidylinositol-specific phospholipase C and phospholipase D (Q28245266)

title

Regulation of eukaryotic phosphatidylinositol-specific phospholipase C and phospholipase D (English)

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author name string

W. D. Singer

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9242915

9 November 2024

H. A. Brown

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9242915

9 November 2024

P. C. Sternweis

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:9242915

full work available at URL

9 November 2024

language of work or name

English

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publication date

1997

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number of pages

35

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inferred from page(s)

https://www.annualreviews.org/doi/pdf/10.1146/annurev.biochem.66.1.475

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https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Annual Review of Biochemistry

9 November 2024

published in

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volume

66

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page(s)

475-509

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cites work

Inositol phosphate biochemistry

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Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

9 November 2024

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Protein kinase C and lipid signaling for sustained cellular responses

9 November 2024

3

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Messenger functions of phosphatidic acid

9 November 2024

4

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

ARF-regulated phospholipase D: a potential role in membrane traffic

9 November 2024

5

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Phosphatidylcholine breakdown and signal transduction

9 November 2024

6

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Phosphoinositide-specific phospholipase C and mitogenic signaling

9 November 2024

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1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins

9 November 2024

8

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https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Structure and regulation of phospholipase D.

9 November 2024

9

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Enzymology of mammalian phospholipases D: in vitro studies.

9 November 2024

10

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https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Studies of inositol phospholipid-specific phospholipase C.

9 November 2024

11

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https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Mammalian phosphoinositide-specific phospholipase C isoenzymes

9 November 2024

12

1 reference

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A mutation in PLC1, a candidate phosphoinositide-specific phospholipase C gene from Saccharomyces cerevisiae, causes aberrant mitotic chromosome segregation

9 November 2024

13

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Genetic and biochemical characterization of a phosphatidylinositol-specific phospholipase C in Saccharomyces cerevisiae

9 November 2024

14

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

The putative phosphoinositide-specific phospholipase C gene, PLC1, of the yeast Saccharomyces cerevisiae is important for cell growth

9 November 2024

15

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Isolation and characterization of temperature-sensitive plc1 mutants of the yeast Saccharomyces cerevisiae.

9 November 2024

16

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Growth of a mutant defective in a putative phosphoinositide-specific phospholipase C of Schizosaccharomyces pombe is restored by low concentrations of phosphate and inositol

9 November 2024

17

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Molecular cloning of the plc1 gene of Schizosaccharomyces pombe, which encodes a putative phosphoinositide-specific phospholipase C.

9 November 2024

18

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

PI-specific phospholipase C "alpha" from sheep seminal vesicles is a proteolytic fragment of PI-PLC delta

9 November 2024

19

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Crystal structure of a mammalian phosphoinositide-specific phospholipase C delta

9 November 2024

20

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

C2 domain conformational changes in phospholipase C-delta 1

9 November 2024

21

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain

9 November 2024

22

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https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

9 November 2024

23

1

343

Kawasaki H

1994

1 reference

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Deletion and site-directed mutagenesis of EF-hand domain of phospholipase C-delta 1: effects on its activity

9 November 2024

24

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Mutation of an EF-hand Ca(2 )-binding motif in phospholipase C of Dictyostelium discoideum: inhibition of activity but no effect on Ca(2 )-dependence

9 November 2024

25

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Protein modules and signalling networks

9 November 2024

26

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https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

An α/β-barrel full of evolutionary trouble

9 November 2024

27

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Structural requirements of phosphatidylinositol-specific phospholipase C delta 1 for enzyme activity

9 November 2024

28

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Enhanced phospholipase C-gamma1 activity produced by association of independently expressed X and Y domain polypeptides

9 November 2024

29

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Crystal structure of the phosphatidylinositol-specific phospholipase C from Bacillus cereus in complex with myo-inositol

9 November 2024

30

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Mutations within a highly conserved sequence present in the X region of phosphoinositide-specific phospholipase C-delta 1.

9 November 2024

31

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Cloning and identification of amino acid residues of human phospholipase C delta 1 essential for catalysis

9 November 2024

32

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Mutational analysis of a putative polyphosphoinositide binding site in phospholipase C-beta 2.

9 November 2024

33

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Phospholipase C-gamma 1 can induce DNA synthesis by a mechanism independent of its lipase activity

9 November 2024

34

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Substrate requirements of bacterial phosphatidylinositol-specific phospholipase C

9 November 2024

37

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Phospholipids chiral at phosphorus. Stereochemical mechanism for the formation of inositol 1-phosphate catalyzed by phosphatidylinositol-specific phospholipase C.

9 November 2024

38

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface

9 November 2024

39

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https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

PH domain: the first anniversary

9 November 2024

40

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Crystal structure at 2.2 A resolution of the pleckstrin homology domain from human dynamin

9 November 2024

41

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Crystal structure of the pleckstrin homology domain from dynamin

9 November 2024

42

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Three-dimensional solution structure of the pleckstrin homology domain from dynamin

9 November 2024

43

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Solution structure of a pleckstrin-homology domain

9 November 2024

44

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Structure of the pleckstrin homology domain from beta-spectrin.

9 November 2024

45

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Structure of the binding site for inositol phosphates in a PH domain

9 November 2024

46

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain

9 November 2024

47

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

The pleckstrin homology domain of phospholipase C-delta 1 binds with high affinity to phosphatidylinositol 4,5-bisphosphate in bilayer membranes.

9 November 2024

48

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

The Association of the C-Terminal Region of β1ΣII Spectrin to Brain Membranes Is Mediated by a pH Domain, Does Not Require Membrane Proteins, and Coincides with a Inositol-1,4,5 Trisphosphate Binding Site

9 November 2024

49

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.

9 November 2024

50

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Identification of the Binding Site for Acidic Phospholipids on the PH Domain of Dynamin: Implications for Stimulation of GTPase Activity

9 November 2024

51

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Phosphoinositide-specific phospholipase C-delta 1 binds with high affinity to phospholipid vesicles containing phosphatidylinositol 4,5-bisphosphate

9 November 2024

53

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Binding of phospholipase C delta 1 to phospholipid vesicles

9 November 2024

55

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

PH domains and phospholipases--a meaningful relationship?

9 November 2024

58

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Binding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase

9 November 2024

60

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Binding of PH domains of beta-adrenergic receptor kinase and beta-spectrin to WD40/beta-transducin repeat containing regions of the beta-subunit of trimeric G-proteins

9 November 2024

61

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Pleckstrin homology domain-mediated membrane association and activation of the beta-adrenergic receptor kinase requires coordinate interaction with G beta gamma subunits and lipid

9 November 2024

62

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

G protein-coupled receptor kinase GRK2 is a phospholipid-dependent enzyme that can be conditionally activated by G protein betagamma subunits

9 November 2024

63

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C

9 November 2024

64

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins

9 November 2024

66

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Structure and ligand recognition of the phosphotyrosine binding domain of Shc

9 November 2024

67

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Structure of the IRS-1 PTB domain bound to the juxtamembrane region of the insulin receptor

9 November 2024

68

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2 )-dependent translocation domain with homology to PKC and GAP

9 November 2024

70

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Extending the C2 domain family: C2s in PKCs delta, epsilon, eta, theta, phospholipases, GAPs, and perforin

9 November 2024

71

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Structure of the first C2 domain of synaptotagmin I: A novel Ca2 /phospholipid-binding fold

9 November 2024

75

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Ca(2 )-bridging mechanism and phospholipid head group recognition in the membrane-binding protein annexin V

9 November 2024

76

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Bipartite Ca2 -binding motif in C2 domains of synaptotagmin and protein kinase C

9 November 2024

77

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Lipid Signaling Enzymes and Surface Dilution Kinetics

9 November 2024

78

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Interfacial enzymology of glycerolipid hydrolases: lessons from secreted phospholipases A2.

9 November 2024

80

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Kinetic analysis of phospholipase C beta isoforms using phospholipid-detergent mixed micelles. Evidence for interfacial catalysis involving distinct micelle binding and catalytic steps

9 November 2024

82

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Phosphatidylinositol 4,5-bisphosphate binding to the pleckstrin homology domain of phospholipase C-delta1 enhances enzyme activity

9 November 2024

83

1 reference

https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq.

9 November 2024

85

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Activation of the β1 isozyme of phospholipase C by α subunits of the Gq class of G proteins

9 November 2024

87

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Purification and characterization of recombinant G16 alpha from Sf9 cells: activation of purified phospholipase C isozymes by G-protein alpha subunits

9 November 2024

90

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Characterization of Gq family G proteins GL1 alpha (G14 alpha), GL2 alpha (G11 alpha), and Gq alpha expressed in the baculovirus-insect cell system

9 November 2024

93

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Identification of G alpha 11 as the phospholipase C-activating G-protein of turkey erythrocytes

9 November 2024

95

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Bradykinin modulates potassium and calcium currents in neuroblastoma hybrid cells via different pertussis toxin-insensitive pathways

9 November 2024

102

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The active role of beta gamma in signal transduction

9 November 2024

103

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Stimulation of phospholipase C by guanine-nucleotide-binding protein beta gamma subunits

9 November 2024

104

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Activation of phosphatidylinositol lipid-specific phospholipase C-beta 3 by G-protein beta gamma subunits

9 November 2024

107

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Isozyme-selective stimulation of phospholipase C-beta 2 by G protein beta gamma-subunits

9 November 2024

109

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Subunits beta gamma of heterotrimeric G protein activate beta 2 isoform of phospholipase C

9 November 2024

110

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Stimulation of phospholipase C-beta 2 by recombinant guanine-nucleotide-binding protein beta gamma dimers produced in a baculovirus/insect cell expression system. Requirement of gamma-subunit isoprenylation for stimulation of phospholipase C.

9 November 2024

111

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Functional significance of beta gamma-subunit carboxymethylation for the activation of phospholipase C and phosphoinositide 3-kinase

9 November 2024

112

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Type-specific regulation of adenylyl cyclase by G protein beta gamma subunits

9 November 2024

113

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Concentration of enzyme-dependent activation of PLC-beta 1 and PLC-beta 2 by G alpha 11 and beta gamma-subunits

9 November 2024

114

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Activation of phospholipase C beta 2 by the alpha and beta gamma subunits of trimeric GTP-binding protein

9 November 2024

115

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Molecular cloning, expression and regulatory activity of G alpha 11- and beta gamma-subunit-stimulated phospholipase C-beta from avian erythrocytes

9 November 2024

116

1 reference

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Pertussis toxin-sensitive activation of phospholipase C by the C5a and fMet-Leu-Phe receptors

9 November 2024

117

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Purification, characterization, and partial amino acid sequence of a G protein-activated phospholipase C from squid photoreceptors

9 November 2024

118

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Squid photoreceptor phospholipase C is stimulated by membrane Gq alpha but not by soluble Gq alpha

9 November 2024

119

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A beta-subclass phosphatidylinositol-specific phospholipase C from squid (Loligo forbesi) photoreceptors exhibiting a truncated C-terminus.

9 November 2024

120

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Isolation of cDNA Clones Encoding Eight Different Human G Protein γ Subunits, Including Three Novel Forms Designated the γ4, γ10, and γ11 Subunits

9 November 2024

123

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Multiple forms of phosphoinositide-specific phospholipase C and different modes of activation

9 November 2024

126

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Carboxyl-terminal fragments of phospholipase C-beta1 with intrinsic Gq GTPase-activating protein (GAP) activity

9 November 2024

128

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The role of carboxyl-terminal basic amino acids in Gqalpha-dependent activation, particulate association, and nuclear localization of phospholipase C-beta1.

9 November 2024

131

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Mutational analysis of phospholipase C-beta 2. Identification of regions required for membrane association and stimulation by guanine-nucleotide-binding protein beta gamma subunits

9 November 2024

132

1 reference

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Proteolytic modification of membrane-associated phospholipase C-beta by mu-calpain enhances its activation by G-protein beta gamma subunits in human platelets

9 November 2024

134

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Endogenous cleavage of phospholipase C-beta 3 by agonist-induced activation of calpain in human platelets

9 November 2024

135

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Identification of a phospholipase C beta2 region that interacts with Gbeta-gamma

9 November 2024

136

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Phospholipase C-beta 1 is a GTPase-activating protein for Gq/11, its physiologic regulator

9 November 2024

137

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Regulation of phospholipase C-beta1 by Gq and m1 muscarinic cholinergic receptor. Steady-state balance of receptor-mediated activation and GTPase-activating protein-promoted deactivation

9 November 2024

138

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Regulation of deactivation of photoreceptor G protein by its target enzyme and cGMP

9 November 2024

139

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GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits

9 November 2024

144

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RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunits

9 November 2024

145

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https://api.crossref.org/works/10.1146/ANNUREV.BIOCHEM.66.1.475

Inositol phospholipids-specific phospholipase C: interaction of the gamma 1 isoform with tyrosine kinase

9 November 2024

146

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Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-gamma 1 complexed with a high affinity binding peptide

9 November 2024

147

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PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254.

9 November 2024

150

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Increase of the Catalytic Activity of Phospholipase C-γ1 by Tyrosine Phosphorylation

9 November 2024

151

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Regulation of Phospholipase C-γ1 by Profilin and Tyrosine Phosphorylation

9 November 2024

152

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Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively

9 November 2024

153

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A site of tyrosine phosphorylation in the C terminus of the epidermal growth factor receptor is required to activate phospholipase C.

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9 November 2024

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9 November 2024

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9 November 2024

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Phospholipase D signaling is essential for meiosis.

9 November 2024

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9 November 2024

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9 November 2024

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Purification and immunological analysis of phospholipase D from castor bean endosperm

9 November 2024

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Purification and characterization of phospholipase D (PLD) from rice (Oryza sativa L.) and cloning of cDNA for PLD from rice and maize (Zea mays L.).

9 November 2024

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Improved purification and biochemical characterization of phospholipase D from cabbage

9 November 2024

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Phospholipase D from Streptomyces antibioticus: cloning, sequencing, expression, and relationship to other phospholipases

9 November 2024

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9 November 2024

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Cloning, nucleotide sequence, and expression in Escherichia coli of the phospholipase D gene from Corynebacterium pseudotuberculosis

9 November 2024

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9 November 2024

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9 November 2024

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9 November 2024

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9 November 2024

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Partial purification and characterization of Arf-sensitive phospholipase D from porcine brain

9 November 2024

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Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family

9 November 2024

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Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5-bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alpha

9 November 2024

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9 November 2024

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9 November 2024

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The phosphatidylcholine pathway of diacylglycerol formation stimulated by phorbol diesters occurs via phospholipase D activation

9 November 2024

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9 November 2024

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Phosphatidylinositol 4,5-bisphosphate synthesis is required for activation of phospholipase D in U937 cells

9 November 2024

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Rat brain cytosol contains a factor which reconstitutes guanine-nucleotide-binding-protein-regulated phospholipase-D activation in HL60 cells previously permeabilized with streptolysin O.

9 November 2024

234

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9 November 2024

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Phospholipase D: a downstream effector of ARF in granulocytes

9 November 2024

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Structure and function of ARF proteins: activators of cholera toxin and critical components of intracellular vesicular transport processes

9 November 2024

238

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Molecular dissection of the secretory pathway

9 November 2024

240

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Different ARF domains are required for the activation of cholera toxin and phospholipase D.

9 November 2024

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9 November 2024

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9 November 2024

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RhoA and a cytosolic 50-kDa factor reconstitute GTP gamma S-dependent phospholipase D activity in human neutrophil subcellular fractions

9 November 2024

246

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A phospholipase D-mediated pathway for generating diacylglycerol in nuclei from Madin-Darby canine kidney cells

9 November 2024

247

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9 November 2024

248

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Synergistic Activation of Rat Brain Phospholipase D by ADP-ribosylation Factor and rhoA p21, and Its Inhibition by Clostridium botulinum C3 Exoenzyme

9 November 2024

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Partially purified RhoA-stimulated phospholipase D activity specifically binds to phosphatidylinositol 4,5-bisphosphate.

9 November 2024

250

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Inhibition of receptor signaling to phospholipase D by Clostridium difficile toxin B. Role of Rho proteins

9 November 2024

251

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Evidence for Rho-mediated agonist stimulation of phospholipase D in rat1 fibroblasts. Effects of Clostridium botulinum C3 exoenzyme.

9 November 2024

252

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Regulation of phospholipase D by protein kinase C.

9 November 2024

254

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Phospholipase D activation in fibroblast membranes by the alpha and beta isoforms of protein kinase C.

9 November 2024

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Regulation of phospholipase D by protein kinase C in human neutrophils. Conventional isoforms of protein kinase C phosphorylate a phospholipase D-related component in the plasma membrane

9 November 2024

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Activation of membrane-bound phospholipase D by protein kinase C in HL60 cells: synergistic action of a small GTP-binding protein RhoA.

9 November 2024

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Regulation of membrane-bound phospholipase D by protein kinase C in HL60 cells. Synergistic action of small GTP-binding protein RhoA.

9 November 2024

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9 November 2024

260

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Phorbol ester treatment of intact rabbit platelets greatly enhances both the basal and guanosine 5'-[gamma-thio]triphosphate-stimulated phospholipase D activities of isolated platelet membranes. Physiological activation of phospholipase D may be sec

9 November 2024

261

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Synergistic activation of phospholipase D by protein kinase C- and G-protein-mediated pathways in streptolysin O-permeabilized HL60 cells

9 November 2024

262

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Reconstitution of GTP-gamma-S-dependent phospholipase D activity with ARF, RhoA, and a soluble 36-kDa protein

9 November 2024

263

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ADP-ribosylation factor functions synergistically with a 50-kDa cytosolic factor in cell-free activation of human neutrophil phospholipase D.

9 November 2024

264

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Low molecular weight GTP-binding proteins in HL-60 granulocytes. Assessment of the role of ARF and of a 50-kDa cytosolic protein in phospholipase D activation.

9 November 2024

265

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Regulation of phospholipase D by tyrosine kinases

9 November 2024

266

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v-Src activates a unique phospholipase D activity that can be distinguished from the phospholipase D activity activated by phorbol esters

9 November 2024

267

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Involvement of Ral GTPase in v-Src-induced phospholipase D activation

9 November 2024

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A Soluble Protein Negatively Regulates Phospholipase D Activity. Partial Purification and Characterization

9 November 2024

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Inhibition of phospholipase D activity by fodrin. An active role for the cytoskeleton

9 November 2024

270

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Multiple forms of phospholipase D inhibitor from rat brain cytosol. Purification and characterization of heat-labile form.

9 November 2024

271

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Phospholipids chiral at phosphorus. Steric course of the reactions catalyzed by phosphatidylserine synthase from Escherichia coli and yeast

9 November 2024

273

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Phospholipase D-catalyzed hydrolysis of phosphatidylcholine occurs with PO bond cleavage

9 November 2024

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Phospholipids chiral at phosphorus. Synthesis of chiral phosphatidylcholine and stereochemistry of phospholipase D

9 November 2024

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Alcohols selectively stimulate phospholipase D-mediated hydrolysis of phosphatidylethanolamine in NIH 3T3 cells

9 November 2024

277

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Ethanolamine is released from glial cells in primary culture on stimulation with foetal calf serum and phorbol ester

9 November 2024

278

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Inositol is the water-soluble product of acetylcholine-stimulated breakdown of phosphatidylinositol in mouse pancreas

9 November 2024

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Differential effects of platelet-derived growth factor, serum and bombesin on phospholipase D-mediated hydrolysis of phosphatidylethanolamine in NIH 3T3 fibroblasts

9 November 2024

280

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Identification of a novel, Ca2 -dependent phospholipase D with preference for phosphatidylserine and phosphatidylethanolamine in Saccharomyces cerevisiae

9 November 2024

281

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Identification of a novel Ca2 -dependent, phosphatidylethanolamine-hydrolyzing phospholipase D in yeast bearing a disruption in PLD1.

9 November 2024

282

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Phospholipase D Hydrolyzes Ether- and Ester-Linked Glycerophospholipids by Different Pathways in MDCK Cells

9 November 2024

284

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Ca2 inhibits guanine nucleotide-activated phospholipase D in neural-derived NG108-15 cells

9 November 2024

285

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Enzymatic synthesis of structural analogs of PAF-acether by phospholipase D-catalysed transphosphatidylation

9 November 2024

286

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Synthesis of 6-phosphatidyl-L-ascorbic acid by phospholipase D.

9 November 2024

287

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Conversion of lysophospholipids to cyclic lysophosphatidic acid by phospholipase D

9 November 2024

288

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Phosphatidic acid activation of protein kinase C-zeta overexpressed in COS cells: comparison with other protein kinase C isotypes and other acidic lipids

9 November 2024

292

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Stimulation by phospholipids of a protein-tyrosine-phosphatase containing two src homology 2 domains

9 November 2024

293

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Raf-1 kinase possesses distinct binding domains for phosphatidylserine and phosphatidic acid. Phosphatidic acid regulates the translocation of Raf-1 in 12-O-tetradecanoylphorbol-13-acetate-stimulated Madin-Darby canine kidney cells

9 November 2024

296

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The effect of GTPase activating protein upon ras is inhibited by mitogenically responsive lipids

9 November 2024

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Accumulation of phosphatidic acid mass and increased de novo synthesis of glycerolipids in platelet-activating-factor-activated human neutrophils

9 November 2024

298

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Phosphatidic acid generation through interleukin 2 (IL-2)-induced alpha-diacylglycerol kinase activation is an essential step in IL-2-mediated lymphocyte proliferation

9 November 2024

299

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The regulation and cellular functions of phosphatidylcholine hydrolysis

9 November 2024

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Purification of a phosphatidic-acid-hydrolysing phospholipase A2 from rat brain

9 November 2024

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Correlation between secretion and phospholipase D activation in differentiated HL60 cells.

9 November 2024

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ARF and PITP restore GTPγS-stimulated protein secretion from cytosol-depleted HL60 cells by promoting PIP2 synthesis

9 November 2024

304

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Coat proteins and vesicle budding

9 November 2024

305

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Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A

9 November 2024

306

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Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein

9 November 2024

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Inhibition by brefeldin A of a Golgi membrane enzyme that catalyses exchange of guanine nucleotide bound to ARF

9 November 2024

308

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Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles

9 November 2024

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Cloning and sequence of multiple forms of phospholipase C

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