Role of S6K1 in regulation of SREBP1c expression in the liver (Q28244621)

Europe PubMed Central

PubMed publication ID

21806970

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21806970

8 December 2024

7

Kenta Hara

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author name string

Shuying Li

1

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Wataru Ogawa

2

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Aki Emi

3

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Kumiko Hayashi

4

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Yoko Senga

5

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Kazuhiro Nomura

6

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Demin Yu

8

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Masato Kasuga

9

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language of work or name

English

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publication date

26 August 2011

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22 July 2011

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Europe PubMed Central

PubMed publication ID

21806970

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21806970

full work available at URL

8 December 2024

https://api.elsevier.com/content/article/PII:S0006291X11012575?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2011.07.038

https://api.elsevier.com/content/article/PII:S0006291X11012575?httpAccept=text/plain

8 December 2024

1 reference

https://api.crossref.org/works/10.1016/J.BBRC.2011.07.038

Biochemical and Biophysical Research Communications

8 December 2024

published in

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volume

412

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issue

2

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page(s)

197-202

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cites work

Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes

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Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease.

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Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells

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Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes

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Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and glucokinase genes in rat hepatocytes

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PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity

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