Nck-2 interacts with focal adhesion kinase and modulates cell motility (Q28214529)

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Yizeng Tu

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Yun Hua

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Ka Chen

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Tang-Long Shen

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Jun-Lin Guan

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Chuanyue Wu

International Journal of Biochemistry & Cell Biology

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language of work or name

English

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publication date

July 2002

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published in

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volume

34

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issue

7

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page(s)

791-805

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cites work

Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Identification of Nck family genes, chromosomal localization, expression, and signaling specificity

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Identification of Grb4/Nckbeta, a src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to Nck

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Nck, a melanoma cDNA encoding a cytoplasmic protein consisting of the src homology units SH2 and SH3

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

The Nck SH2/SH3 adaptor protein: a regulator of multiple intracellular signal transduction events

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Focal adhesion kinase: structure and signalling.

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Focal adhesion kinase and associated proteins

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Integrins and signal transduction pathways: the road taken

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Integrins: emerging paradigms of signal transduction

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Signaling through focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Focal adhesion kinase in integrin signaling

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Differential regulation of cell migration and cell cycle progression by FAK complexes with Src, PI3K, Grb7 and Grb2 in focal contacts

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Phosphorylation of focal adhesion kinase (pp125(FAK)) is increased in human keratinocytes induced to migrate by extracellular matrices.

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Biochemical signals and biological responses elicited by the focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Focal adhesion kinase: a regulator of focal adhesion dynamics and cell movement

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Focal adhesion kinase functions as a receptor-proximal signaling component required for directed cell migration

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Identification of p130Cas as a Mediator of Focal Adhesion Kinase–promoted Cell Migration

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Integrin activation and cytoskeletal interaction are essential for the assembly of a fibronectin matrix

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Expression of mutated Nck SH2/SH3 adaptor respecifies mesodermal cell fate in Xenopus laevis development

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Domain requirements for the Dock adapter protein in growth- cone signaling

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Interaction between focal adhesion kinase and Crk-associated tyrosine kinase substrate p130Cas

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein.

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Nckbeta adapter regulates actin polymerization in NIH 3T3 fibroblasts in response to platelet-derived growth factor bb

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Interaction of the Nck adapter protein with p21-activated kinase (PAK1)

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Isolation of a NCK-associated kinase, PRK2, an SH3-binding protein and potential effector of Rho protein signaling

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck.

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Rac GTPase interacts with GAPs and target proteins through multiple effector sites.

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

A Drosophila homolog of the Rac- and Cdc42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Cell adhesion regulates the interaction between Nck and p21-activated kinase

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

PAK promotes morphological changes by acting upstream of Rac.

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Identification and kinetic analysis of the interaction between Nck-2 and DOCK180

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

A critical role of the PINCH-integrin-linked kinase interaction in the regulation of cell shape change and migration

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Integrin-linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Control of adhesion-dependent cell survival by focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Inhibition of Cell Spreading by Expression of the C-Terminal Domain of Focal Adhesion Kinase (FAK) Is Rescued by Coexpression of Src or Catalytically Inactive FAK: a Role for Paxillin Tyrosine Phosphorylation

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Inhibition of pp125FAK in cultured fibroblasts results in apoptosis

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021

Src homology 3 domain-dependent interaction of Nck-2 with insulin receptor substrate-1

1 reference

https://api.crossref.org/works/10.1016/S1357-2725(02)50002-X

7 January 2021