The role of transsignalling via the agonistic soluble IL-6 receptor in human diseases (Q28214190)

Biochimica et Biophysica Acta

Europe PubMed Central

title

The role of transsignalling via the agonistic soluble IL-6 receptor in human diseases (English)

0 references

author name string

Karl-Josef Kallen

series ordinal

1

0 references

language of work or name

English

0 references

publication date

11 November 2002

0 references

published in

0 references

volume

1592

0 references

issue

3

0 references

page(s)

323-43

0 references

cites work

Interleukin-6 in biology and medicine

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Gp130 and the interleukin-6 family of cytokines

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Combination of Interleukin-6 and Soluble Interleukin-6 Receptors Induces Differentiation and Activation of JAK-STAT and MAP Kinase Pathways in MG-63 Human Osteoblastic Cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin-6 production in B-cell neoplasias and Castleman's disease: evidence for an additional paracrine loop

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Blockade of interleukin 6 trans signaling suppresses T-cell resistanceagainst apoptosis in chronic intestinal inflammation: Evidence in Crohn diseaseand experimental colitis in vivo

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Increased osteoclast development after estrogen loss: mediation by interleukin-6

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Bone marrow, cytokines, and bone remodeling. Emerging insights into the pathophysiology of osteoporosis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Induction of interleukin-6 synthesis in the myocardium. Potential role in postreperfusion inflammatory injury

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Evidence for the involvement of interleukin 6 in experimental cancer cachexia

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Serum soluble interleukin 6 (IL-6) receptor and IL-6/soluble IL-6 receptor complex in systemic juvenile rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin 6 induces human immunodeficiency virus expression in infected monocytic cells alone and in synergy with tumor necrosis factor alpha by transcriptional and post-transcriptional mechanisms

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The therapeutic potential of interleukin-6 hyperagonists and antagonists

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

New developments in IL-6 dependent biology and therapy: where do we stand and what are the options?

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Soluble interleukin-6 receptors released from T cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanism

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

A soluble interleukin 6 receptor isolated from conditioned medium of human breast cancer cells is encoded by a differentially spliced mRNA

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

High-level production of alternatively spliced soluble interleukin-6 receptor in serum of patients with adult T-cell leukaemia/HTLV-I-associated myelopathy

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The soluble interleukin-6 receptor is generated by shedding

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

IL-6 type cytokine receptor complexes: hexamer, tetramer or both?

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Homology of the p40 subunit of natural killer cell stimulatory factor (NKSF) with the extracellular domain of the interleukin-6 receptor

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

A family of cytokine-inducible inhibitors of signalling

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Structure and function of a new STAT-induced STAT inhibitor

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Soluble receptors for cytokines and growth factors: generation and biological function

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The function of the soluble interleukin 6 (IL-6) receptor in vivo: sensitization of human soluble IL-6 receptor transgenic mice towards IL-6 and prolongation of the plasma half-life of IL-6.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Inactivation of interleukin-6 by neutrophil proteases at sites of inflammation. Protective effects of soluble IL-6 receptor chains

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Receptor recognition sites of cytokines are organized as exchangeable modules. Transfer of the leukemia inhibitory factor receptor-binding site from ciliary neurotrophic factor to interleukin-6.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Hepatocellular hyperplasia, plasmacytoma formation, and extramedullary hematopoiesis in interleukin (IL)-6/soluble IL-6 receptor double-transgenic mice

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Coexpression of IL-6 and soluble IL-6R causes nodular regenerative hyperplasia and adenomas of the liver.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Nodular transformation (nodular "regenerative" hyperplasia) of the liver. A clinicopathologic study of 30 cases.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Enzyme pattern and marker antigens in nodular “regenerative” hyperplasia of the liver

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Transformation of hepatic cell adenoma to hepatocellular carcinoma due to oral contraceptive use.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Nodular regenerative hyperplasia of the liver associated with macroglobulinemia. A clue to the pathogenesis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Retrograde inflammatory signaling from neutrophils to endothelial cells by soluble interleukin-6 receptor alpha

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Oncostatin M is a proinflammatory mediator. In vivo effects correlate with endothelial cell expression of inflammatory cytokines and adhesion molecules

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Novel pathogenic mechanism of microbial metalloproteinases: liberation of membrane-anchored molecules in biologically active form exemplified by studies with the human interleukin-6 receptor

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Pore-forming toxins trigger shedding of receptors for interleukin 6 and lipopolysaccharide.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

C-reactive protein: a physiological activator of interleukin 6 receptor shedding.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The soluble interleukin 6 receptor: mechanisms of production and implications in disease

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The IL-6-soluble IL-6Ralpha autocrine loop of endothelial activation as an intermediate between acute and chronic inflammation: an experimental model involving thrombin

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

IL-6 Receptor Independent Stimulation of Human gp130 by Viral IL-6

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Atherogenic properties of enzymatically degraded LDL: selective induction of MCP-1 and cytotoxic effects on human macrophages

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Enzymatically modified, nonoxidized LDL induces selective adhesion and transmigration of monocytes and T-lymphocytes through human endothelial cell monolayers

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Enzymatically Degraded, Nonoxidized LDL Induces Human Vascular Smooth Muscle Cell Activation, Foam Cell Transformation, and Proliferation

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Atherosclerosis — An Inflammatory Disease

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Association between hepatitis C virus seropositivity, carotid-artery plaque, and intima-media thickening

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Removal of LDL from plasma by adsorption reduces adhesion molecules on mononuclear cells in patients with arteriosclerosis obliterans

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Serum concentrations of proinflammatory cytokines in Graves' disease: effect of treatment, thyroid function, ophthalmopathy and cigarette smoking

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

A cytotoxic nonstructural protein, NS1, of human parvovirus B19 induces activation of interleukin-6 gene expression

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Cytomegalovirus induction of interleukin-6 in lung fibroblasts occurs independently of active infection and involves a G protein and the transcription factor, NF-kappaB.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Association of parvoviruses with rheumatoid arthritis of humans

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Human parvovirus B19-associatedarthritis in children

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Polyarteritis nodosa and parvovirus B19 infection

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Wild-type Puumala hantavirus infection induces cytokines, C-reactive protein, creatinine, and nitric oxide in cynomolgus macaques

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Paramyxoviruses and Paget's disease: the affirmative view

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin-6, IL-6 receptor, and IL-6 nuclear factor gene expression in paget's disease

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Could endogenous self-peptides presented by dendritic cells initiate rheumatoid arthritis?

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

1 reference

7 January 2021

Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Differential effects of interleukins 10 and 4 on the production of interleukin‐6 by blood and synovium monocytes in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The role of oncostatin M in animal and human connective tissue collagen turnover and its localization within the rheumatoid joint

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Synergistic effects of glycoprotein 130 binding cytokines in combination with interleukin-1 on cartilage collagen breakdown

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Decrease of interleukin 6 during the first 12 months is a prognostic marker for clinical outcome during 36 months treatment with disease-modifying anti-rheumatic drugs

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Nurse-like cells from bone marrow and synovium of patients with rheumatoid arthritis promote survival and enhance function of human B cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin (IL)-6 and Its Soluble Receptor Induce TIMP-1 Expression in Synoviocytes and Chondrocytes, and Block IL-1-induced Collagenolytic Activity

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

IL-6 inhibits the proliferation of fibroblastic synovial cells from rheumatoid arthritis patients in the presence of soluble IL-6 receptor

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin-6 deficiency increases inflammatory bone destruction

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin 6 is required for the development of collagen-induced arthritis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin 6 plays a key role in the development of antigen-induced arthritis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Impaired immune and acute-phase responses in interleukin-6-deficient mice.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Tumor necrosis factor-alpha autoregulates interleukin-6 synthesis via activation of protein kinase C. Function of sphingosine 1-phosphate and phosphatidylcholine-specific phospholipase C.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Tumor necrosis factor-alpha induces interleukin-6 mRNA and protein in human granulosa luteinizing cells via protein tyrosine kinase without involving ceramide

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Treatment of Rheumatoid Arthritis with a Recombinant Human Tumor Necrosis Factor Receptor (p75)–Fc Fusion Protein

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

A trial of etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Effect of cyclosporin A on interleukin-6 and soluble interleukin-2 receptor in patients with rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The Effect of Azathioprine on Serum Levels of Interleukin 6 and Soluble Interleukin 2 Receptor

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Treatment of rheumatoid synovitis with anti-reshaping human interleukin-6 receptor monoclonal antibody: use of rheumatoid arthritis tissue implants in the SCID mouse model.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Humanized antibody to human interleukin-6 receptor inhibits the development of collagen arthritis in cynomolgus monkeys

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

IL-6 functions in cynomolgus monkeys blocked by a humanized antibody to human IL-6 receptor

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Anti-interleukin 6 receptor antibody treatment in rheumatic disease

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Cloning of novel soluble gp130 and detection of its neutralizing autoantibodies in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

A possible role for soluble IL-6 receptor in the pathogenesis of systemic onset juvenile chronic arthritis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Correlation of serum interleukin-6 levels with joint involvement and thrombocytosis in systemic juvenile rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Serum interleukin 12 concentration in juvenile chronic arthritis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Inflammatory cytokines and cytokine antagonists in whole blood cultures of patients with systemic juvenile chronic arthritis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Juvenile rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Establishment and characterization of a human B cell line from the lung tissue of a patient with scleroderma; extraordinary high level of IL-6 secretion by stimulated fibroblasts

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Serum levels of interleukin-6 and interleukin-10 correlate with total skin thickness score in patients with systemic sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Endogenous IL-1alpha from systemic sclerosis fibroblasts induces IL-6 and PDGF-A.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Cyclosporin A and iloprost treatment of systemic sclerosis: clinical results and interleukin-6 serum changes after 12 months of therapy

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Enhanced production of interleukin-6 (IL-6), oncostatin M and soluble IL-6 receptor by cultured peripheral blood mononuclear cells from patients with systemic sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Analysis of soluble and cell surface factors regulating anti-DNA topoisomerase I autoantibody production demonstrates synergy between Th1 and Th2 autoreactive T cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Autoreactive T cells to topoisomerase I in monozygotic twins discordant for systemic sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Serum and urinary interleukin-6 in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Imbalance between interleukin-6 and adrenomedullin mRNA levels in peripheral blood mononuclear cells of patients with lupus nephritis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin 6 promotes murine lupus in NZB/NZW F1 mice

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

IgG1 plasmacytosis in interleukin 6 transgenic mice

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Regulation of mesangial cell proliferation

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Mitogenic effect of platelet-derived growth factor in human glomerular mesangial cells: modulation and/or suppression by inflammatory cytokines

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Selective induction of MCP-1 in human mesangial cells by the IL-6/sIL-6R complex

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Platelet-derived growth factor, interleukin (IL)-1 beta, IL-6R and tumor necrosis factor-alpha in IgA nephropathy. An immunohistochemical study

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

IL-6 receptor blockage inhibits the onset of autoimmune kidney disease in NZB/W F1 mice

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Anti-interleukin-6 and soluble interleukin-6 receptor in systemic lupus erythematosus

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Expression of IL-2R, IL-4R, IL-6R on peripheral blood lymphocytes in systemic lupus erythematosus and correlation with disease activity: a prospective study

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Role of different dialysis membranes in the release of interleukin-6-soluble receptor in uremic patients

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Circulating levels of interleukin-6, its soluble receptor and interleukin-6/interleukin-6 receptor complexes in patients with type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin-6 and soluble interleukin-6 receptor in the colonic mucosa of inflammatory bowel disease

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Tissue-specific autoregulation of the stat3 gene and its role in interleukin-6-induced survival signals in T cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

A bioactive designer cytokine for human hematopoietic progenitor cell expansion

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The gp130-stimulating designer cytokine hyper-IL-6 promotes the expansion of human hematopoietic progenitor cells capable to differentiate into functional dendritic cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Endothelin receptor in osteoblastic cells is coupled to multiple messenger signals

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

In vivo priming of T cells against cryptic determinants by dendritic cells exposed to interleukin 6 and native antigen.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Impaired activity of thiol-dependent ATPases in rheumatoid mononuclear cell membranes

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Tolerance, danger, and the extended family

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Graft tolerance: a duel of two signals

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Serum interleukin-6, soluble interleukin-6 receptor and soluble gp130 exhibit different patterns of age- and menopause-related changes

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin-6 (IL-6) production by astrocytes: autocrine regulation by IL-6 and the soluble IL-6 receptor.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

IL-6-deficient mice are resistant to the induction of experimental autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin-6 functions in autoimmune encephalomyelitis: a study in gene-targeted mice

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

CSF and serum levels of soluble interleukin-6 receptors (sIL-6R and sgp130), but not of interleukin-6 are altered in multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

No association between anti-myelin oligodendrocyte glycoprotein antibodies and serum/cerebrospinal fluid levels of the soluble interleukin-6 receptor complex in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Enhancement of beta-amyloid precursor protein transcription and expression by the soluble interleukin-6 receptor/interleukin-6 complex.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Occurrence of interleukin-6 in cortical plaques of Alzheimer's disease patients may precede transformation of diffuse into neuritic plaques

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The participation of interleukin-6, a stress-inducible cytokine, in the pathogenesis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Serum interleukin-6 and interleukin-6 soluble receptor in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Decreased soluble interleukin-6 receptor in cerebrospinal fluid of patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Discriminant power of combined cerebrospinal fluid tau protein and of the soluble interleukin-6 receptor complex in the diagnosis of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin-2 and interleukin-6 in schizophrenia and mania: Effects of neuroleptics and mood stabilizers

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Relationships between interleukin-6 activity, acute phase proteins, and function of the hypothalamic-pituitary-adrenal axis in severe depression

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Elevated serum interleukin-6 (IL-6) and IL-6 receptor concentrations in posttraumatic stress disorder following accidental man-made traumatic events

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin-6-deficient mice develop mature-onset obesity

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Plasma concentrations of interleukin-1-beta, interleukin-6 and tumor necrosis factor-alpha, and of their soluble receptors and receptor antagonist in anorexia nervosa

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Basic mechanisms in congestive heart failure. Recognizing the role of proinflammatory cytokines

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Inflammatory mediators in heart failure: homogeneity through heterogeneity

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Angiotensin-converting enzyme inhibitors and cytokines in heart failure: dose and effect?

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Use of targeted anticytokine treatments in heart failure

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Plasma cytokine parameters and mortality in patients with chronic heart failure

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Safety and efficacy of a soluble P75 tumor necrosis factor receptor (Enbrel, etanercept) in patients with advanced heart failure.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

gp130 plays a critical role in pressure overload-induced cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Osteoclasts Are Present in gp130-Deficient Mice*

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Postnatally induced inactivation of gp130 in mice results in neurological, cardiac, hematopoietic, immunological, hepatic, and pulmonary defects

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Cardiotrophin 1 (CT-1) inhibition of cardiac myocyte apoptosis via a mitogen-activated protein kinase-dependent pathway. Divergence from downstream CT-1 signals for myocardial cell hypertrophy

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Apoptosis in the failing human heart

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Cytokine network in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Activation of the cardiac interleukin-6 system in advanced heart failure

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Negative inotropic effects of cytokines on the heart mediated by nitric oxide

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Expression and self-regulatory function of cardiac interleukin-6 during endotoxemia

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Decreased expression of tumor necrosis factor-alpha in failing human myocardium after mechanical circulatory support : A potential mechanism for cardiac recovery

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Relationship between plasma level of cardiotrophin-1 and left ventricular mass index in patients with dilated cardiomyopathy

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Myocardial gene expression of leukaemia inhibitory factor, interleukin-6 and glycoprotein 130 in end-stage human heart failure

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Modification of viral myocarditis in mice by interleukin-6

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Overexpression of interleukin-6 aggravates viral myocarditis: impaired increase in tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Age-associated differences in cardiovascular inflammatory gene induction during endotoxic stress

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

ERK and p38 MAPK, but not NF-kappaB, are critically involved in reactive oxygen species-mediated induction of IL-6 by angiotensin II in cardiac fibroblasts

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin-6 family of cytokines mediate angiotensin II-induced cardiac hypertrophy in rodent cardiomyocytes

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Autocrine/Paracrine secretion of IL-6 family cytokines causes angiotensin II-induced delayed STAT3 activation

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Significance of ERK cascade compared with JAK/STAT and PI3-K pathway in gp130-mediated cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Effect of high- versus low-dose angiotensin converting enzyme inhibition on cytokine levels in chronic heart failure

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Blood-pressure reduction and cardiovascular risk in HOPE study

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Giant cell myocarditis, in a patient with Crohn's disease, treated with etanercept--a tumour necrosis factor-alpha antagonist

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Functional profile of tissue-infiltrating and circulating CD68 cells in giant cell arteritis. Evidence for two components of the disease

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Cardiac myocytes produce interleukin-6 in culture and in viable border zone of reperfused infarctions

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

A chronic mouse model of myocardial ischemia-reperfusion: essential in cytokine studies

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Regulation of CCAAT/Enhancer binding protein, interleukin-6, interleukin-6 receptor, and gp130 expression during myocardial ischemia/reperfusion

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin 6 induction in the canine myocardium after cardiopulmonary bypass

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin-6 derived from hypoxic myocytes promotes neutrophil-mediated reperfusion injury in myocardium

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

IL-6 Release after Intestinal Ischemia/Reperfusion in Rats Is under Partial Control of TNF

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Splanchnic origin of cytokines in a porcine model of mesenteric ischemia-reperfusion

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Decreased soluble interleukin-6 receptor in patients with acute myocardial infarction

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Circulating interleukin-6 and interleukin-6 receptors in patients with acute and recent myocardial infarction

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The interleukin-6 -174 G/C promoter polymorphism is associated with risk of coronary heart disease and systolic blood pressure in healthy men.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Increased intrahepatic messenger RNA expression of interleukins 2, 6, and 8 in human cirrhosis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Expression of the hepatocyte growth factor-like protein gene in human hepatocellular carcinoma and interleukin-6-induced increased expression in hepatoma cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Hepatocyte growth factor/scatter factor (HGF/SF) signals via the STAT3/APRF transcription factor in human hepatoma cells and hepatocytes

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Effect of IL-6 overexpression on the metastatic potential of rat hepatocellular carcinoma cells.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Factors influencing the effect of the soluble IL-6 receptor on IL-6 responses in HepG2 hepatocytes

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Elevated levels of interleukin-8 in serum are associated with hepatitis C virus infection and resistance to interferon therapy

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Hepatic regeneration induces transient acute phase reaction: systemic elevation of acute phase reactants and soluble cytokine receptors

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Combined interleukin 6 and soluble interleukin 6 receptor accelerates murine liver regeneration

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Liver regeneration induced by a designer human IL-6/sIL-6R fusion protein reverses severe hepatocellular injury.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Possible role of human interleukin-6 and soluble interleukin-6 receptor in hepatitis B virus infection

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Chinese hamster ovarian cells transfected with the murine interleukin-6 gene cause hypercalcemia as well as cachexia, leukocytosis and thrombocytosis in tumor-bearing nude mice

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin-11: a new cytokine critical for osteoclast development

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Modulation of osteoclast differentiation by local factors

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Transcriptional activation of the p21(WAF1,CIP1,SDI1) gene by interleukin-6 type cytokines. A prerequisite for their pro-differentiating and anti-apoptotic effects on human osteoblastic cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Osteoblast Programmed Cell Death (Apoptosis): Modulation by Growth Factors and Cytokines

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

STAT3 activation in stromal/osteoblastic cells is required for induction of the receptor activator of NF-kappaB ligand and stimulation of osteoclastogenesis by gp130-utilizing cytokines or interleukin-1 but not 1,25-dihydroxyvitamin D3 or parathyroi

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin (IL)-6 induction of osteoclast differentiation depends on IL-6 receptors expressed on osteoblastic cells but not on osteoclast progenitors

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Expression levels of gp130 in bone marrow stromal cells determine the magnitude of osteoclastogenic signals generated by IL-6-type cytokines

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Stimulation by parathyroid hormone of interleukin-6 and leukemia inhibitory factor expression in osteoblasts is an immediate-early gene response induced by cAMP signal transduction

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Adenyl cyclase and interleukin 6 are downstream effectors of parathyroid hormone resulting in stimulation of bone resorption

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin-6 enhances hypercalcemia and bone resorption mediated by parathyroid hormone-related protein in vivo

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Periodontal disease and risk of coronary heart disease

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Surface-associated material from the bacterium Actinobacillus actinomycetemcomitans contains a peptide which, in contrast to lipopolysaccharide, directly stimulates fibroblast interleukin-6 gene transcription.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Role of soluble interleukin-6 receptor in inflamed gingiva for binding of interleukin-6 to gingival fibroblasts

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Impairment of gingival fibroblast adherence by IL-6/sIL-6R.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Identification of periodontal pathogens in atheromatous plaques.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Periodontal disease and risk of cerebrovascular disease: the first national health and nutrition examination survey and its follow-up study

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Examining the link between coronary heart disease and the elimination of chronic dental infections

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Serum Soluble Interleukin-6 Receptor and Biochemical Markers of Bone Metabolism Show Significant Variations During the Menstrual Cycle

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Correlation of estradiol, parathyroid hormone, interleukin-6, and soluble interleukin-6 receptor during the normal menstrual cycle

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

17 beta-estradiol inhibits interleukin-6 production by bone marrow-derived stromal cells and osteoblasts in vitro: a potential mechanism for the antiosteoporotic effect of estrogens

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Estrogen receptor impairs interleukin-6 expression by preventing protein binding on the NF-kappaB site

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Repression of the Interleukin-6 Promoter by Estrogen Receptor Is Mediated by NF-κB and C/EBPβ

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Regulation of the gp80 and gp130 subunits of the IL-6 receptor by sex steroids in the murine bone marrow

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Oestrogens prevent the increase of human serum soluble interleukin-6 receptor induced by ovariectomy in vivo and decrease its release in human osteoblastic cells in vitro

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Mode of action of interleukin-6 on mature osteoclasts. Novel interactions with extracellular Ca2 sensing in the regulation of osteoclastic bone resorption

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Cytokines and bone loss in a 5-year longitudinal study--hormone replacement therapy suppresses serum soluble interleukin-6 receptor and increases interleukin-1-receptor antagonist: the Danish Osteoporosis Prevention Study

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Biochemical markers of bone metabolism reflect osteoclastic and osteoblastic activity in multiple myeloma

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Menstrual cycle-specific inhibition of the proliferation of endometrial stromal cells by interleukin 6 and its soluble receptor.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Increased interleukin-6 levels in peritoneal fluid of infertile patients with active endometriosis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Generation of plasmacytomas with the chromosomal translocation t(12;15) in interleukin 6 transgenic mice.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

1 reference

7 January 2021

Antitumor activity of thalidomide in refractory multiple myeloma

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Increased and highly stable levels of functional soluble interleukin-6 receptor in sera of patients with monoclonal gammopathy

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Major role of the soluble interleukin‐6/interleukin‐6 receptor complex for the proliferation of interleukin‐6‐dependent human myeloma cell lines

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Differential interleukin-6 (IL-6) responses of three established myeloma cell lines in the presence of soluble human IL-6 receptors

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Soluble interleukin-6 receptor (sIL-6R), a new prognostic factor in multiple myeloma

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The prognostic value of soluble interleukin-6 receptor in patients with multiple myeloma

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

IL-6 upregulates its own receptor on some human myeloma cell lines

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Protein kinase C delta and eta isoenzymes control the shedding of the interleukin 6 receptor alpha in myeloma cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Shedding of interleukin-6 receptor and tumor necrosis factor alpha. Contribution of the stalk sequence to the cleavage pattern of transmembrane proteins

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin-6 inhibits apoptosis of malignant plasma cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The IL-6 receptor antagonist SANT-7 overcomes bone marrow stromal cell-mediated drug resistance of multiple myeloma cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Dexamethasone induces apoptosis of multiple myeloma cells in a JNK/SAP kinase independent mechanism

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Soluble IL-6R alpha upregulated IL-6, MMP-1 and MMP-2 secretion in bone marrow stromal cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin 6 induces the expression of vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Experimental metastasis is suppressed in MMP-9-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Gelatinase A activity directly modulates melanoma cell adhesion and spreading.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Detection of membrane and soluble interleukin-6 receptor in lymphoid malignancies

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Acute myeloblastic leukaemia cells produce soluble interleukin 6 receptor by a mechanism of alternative splicing

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Soluble IL-6 receptor levels in AML patients

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Clinical correlates of elevated serum levels of interleukin 6 in patients with untreated Hodgkin's disease

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Hodgkin and Reed-Sternberg cells express interleukin 6 and interleukin 6 receptors

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

STAT3 is constitutively activated in Hodgkin cell lines

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Transformation of primary human endothelial cells by Kaposi's sarcoma-associated herpesvirus

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Reciprocal regulatory interaction between human herpesvirus 8 and human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Human herpesvirus 8 encodes a homolog of interleukin-6.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Kaposi's sarcoma-associated human herpesvirus-8 encodes homologues of macrophage inflammatory protein-1 and interleukin-6.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

In situ polymerase chain reaction-based localization studies support role of human herpesvirus-8 as the cause of two AIDS-related neoplasms: Kaposi's sarcoma and body cavity lymphoma

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Cellular tropism and viral interleukin-6 expression distinguish human herpesvirus 8 involvement in Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman's disease

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Serum viral interleukin-6 in AIDS-related multicentric Castleman disease

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

AIDS-associated Kaposi's sarcoma (KS) cells express oncostatin M (OM)-specific receptor but not leukemia inhibitory factor/OM receptor or interleukin-6 receptor. Complete block of OM-induced KS cell growth and OM binding by anti-gp130 antibodies

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The soluble form of the IL-6 receptor (sIL-6R alpha) is a potent growth factor for AIDS-associated Kaposi's sarcoma (KS) cells; the soluble form of gp130 is antagonistic for sIL-6R alpha-induced AIDS-KS cell growth

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Brief report: alleviation of systemic manifestations of Castleman's disease by monoclonal anti-interleukin-6 antibody

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Production of interleukins in human immunodeficiency virus-1-replicating lymph nodes

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

IL-6 receptor (CD126'IL-6R') expression is increased on monocytes and B lymphocytes in HIV infection

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Induction of HIV-1 replication in latently infected CD4 T cells using a combination of cytokines

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin 18 stimulates HIV type 1 in monocytic cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Plasma bioavailable interleukin-6 is elevated in human immunodeficiency virus-infected patients who experience herpesvirus-associated immune restoration disease after start of highly active antiretroviral therapy.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

In vivo role of IL-6 on the viral load and on immunological abnormalities of HIV-infected patients

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Immunohistochemical localization of interleukin-6 and its receptor in benign, premalignant and malignant prostate tissue

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3′-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Plasma levels of interleukin-6 and its soluble receptor are associated with prostate cancer progression and metastasis

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin-6 functions as an autocrine growth factor in human bladder carcinoma cell linesin vitro

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Proliferation of human non-small-cell lung cancer cell lines: role of interleukin-6

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Enhancement of interleukin 6 cytostatic effect on human breast carcinoma cells by soluble IL-6 receptor from urine and reversion by monoclonal antibody

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Expression of interleukin-6, interleukin-6 receptor, and glycoprotein 130 correlates with good prognoses for patients with breast carcinoma

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Interleukin-6 (IL-6) functions as an autocrine growth factor in cervical carcinomas in vitro

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Loss of IL-6 receptor expression in cervical carcinoma cells inhibits autocrine IL-6 stimulation: abrogation of constitutive monocyte chemoattractant protein-1 production

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Soluble interleukin-6 receptor activates the human papillomavirus type 18 long control region in SW756 cervical carcinoma cells in a STAT3-dependent manner

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

The designer cytokine hyper-IL-6 mediates growth inhibition and GM-CSF-dependent rejection of B16 melanoma cells

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Genetically modified tumour vaccines (GMTV) in melanoma clinical trials

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Generation of tumor-reactive CTL against the tumor-associated antigen HER2 using retrovirally transduced dendritic cells derived from CD34 hemopoietic progenitor cells.

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Optimizing therapeutic strategies to inhibit circulating soluble target molecules with monoclonal antibodies: example of the soluble IL-6 receptors

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Extramedullary expansion of hematopoietic progenitor cells in interleukin (IL)-6-sIL-6R double transgenic mice

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Astrocytic alterations in interleukin-6/Soluble interleukin-6 receptor alpha double-transgenic mice

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

Increased IL-6-production by cells isolated from the fibrous bone dysplasia tissues in patients with McCune-Albright syndrome

1 reference

https://api.crossref.org/works/10.1016/S0167-4889(02)00325-7

7 January 2021

10.1016/S0167-4889(02)00325-7

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

12421676

1 reference

Consolidated OpenCitations Corpus – April 2017