Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity (Q28213409)

27 March 2017

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Shashi Prajapati

1

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Udit Verma

2

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Yumi Yamamoto

3

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Youn Tae Kwak

4

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Richard B Gaynor

5

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S. Prajapati

1

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27 March 2017

U. Verma

2

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27 March 2017

Y. Yamamoto

3

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27 March 2017

Y. T. Kwak

4

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27 March 2017

R. B. Gaynor

5

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27 March 2017

language of work or name

English

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publication date

16 January 2004

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29 October 2003

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Journal of Biological Chemistry

27 March 2017

published in

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27 March 2017

volume

279

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27 March 2017

issue

3

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27 March 2017

page(s)

1739-46

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1739-1746

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NF-kappa B: ten years after

27 March 2017

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How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

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IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

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Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

21 January 2018

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TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90

21 January 2018

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Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation

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IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1.

21 January 2018

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IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein

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HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation

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Limb and skin abnormalities in mice lacking IKKalpha

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Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

21 January 2018

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Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

21 January 2018

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Protein phosphatase 2A interacts with and directly dephosphorylates RelA

21 January 2018

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Human T-lymphotropic virus type I tax activates I-kappa B kinase by inhibiting I-kappa B kinase-associated serine/threonine protein phosphatase 2A.

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21 January 2018

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21 January 2018

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21 January 2018

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TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

21 January 2018

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21 January 2018

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IkappaB kinase alpha (IKKalpha) regulation of IKKbeta kinase activity

21 January 2018

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21 January 2018

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Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNK MAPK pathways

21 January 2018

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21 January 2018

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21 January 2018

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p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation

21 January 2018

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21 January 2018

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Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M306273200

1 reference