Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis (Q28212224)

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6 November 2019

title

Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis (English)

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6 November 2019

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4

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6 November 2019

Jerry Adams

5

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6 November 2019

Andreas Strasser

6

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6 November 2019

author name string

G V Putcha

1

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6 November 2019

K L Moulder

2

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6 November 2019

J P Golden

3

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6 November 2019

E M Johnson

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6 November 2019

language of work or name

English

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publication date

1 March 2001

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6 November 2019

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6 November 2019

volume

29

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6 November 2019

issue

3

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6 November 2019

page(s)

615-628

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Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

6 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Translocation of C. elegans CED-4 to nuclear membranes during programmed cell death

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Signal transduction by the JNK group of MAP kinases

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

BAX is required for neuronal death after trophic factor deprivation and during development

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Placement of the BCL2 family member BAX in the death pathway of sympathetic neurons activated by trophic factor deprivation.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Staurosporine-induced neuronal death: multiple mechanisms and methodological implications

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Analysis of the Mechanism of Loss of Trophic Factor Dependence Associated with Neuronal Maturation: A Phenotype Indistinguishable fromBaxDeletion

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

The death programme in cultured sympathetic neurones can be suppressed at the posttranslational level by nerve growth factor, cyclic AMP, and depolarization

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Chronic depolarization prevents programmed death of sympathetic neurons in vitro but does not support growth: requirement for Ca2 influx but not Trk activation

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Molecular Cloning of a Novel Polypeptide, DP5, Induced during Programmed Neuronal Death

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Techniques in the tissue culture of rat sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Why do neurons die when deprived of trophic factor?

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Role of Ca2 channels in the ability of membrane depolarization to prevent neuronal death induced by trophic-factor deprivation: evidence that levels of internal Ca2 determine nerve growth factor dependence of sympathetic ganglion cells

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Spatially and Functionally Distinct Roles of the PI3-K Effector Pathway during NGF Signaling in Sympathetic Neurons

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Expression of the SM-20 gene promotes death in nerve growth factor-dependent sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Motoneuron Apoptosis Is Blocked by CEP-1347 (KT 7515), a Novel Inhibitor of the JNK Signaling Pathway

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

The release of cytochrome c from mitochondria during apoptosis of NGF-deprived sympathetic neurons is a reversible event

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Ras regulates sympathetic neuron survival by suppressing the p53-mediated cell death pathway

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cells

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Blocking cytochrome c activity within intact neurons inhibits apoptosis.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Bim: a novel member of the Bcl-2 family that promotes apoptosis

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Cell death during development of the nervous system

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Naturally occurring and induced neuronal death in the chick embryo in vivo requires protein and RNA synthesis: Evidence for the role of cell death genes

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Rapid hybridoma screening method for the identification of monoclonal antibodies to low-abundance cytoplasmic proteins

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Phosphorylation of c-jun mediated by MAP kinases.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

BAX translocation is a critical event in neuronal apoptosis: regulation by neuroprotectants, BCL-2, and caspases

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Inhibition of apoptotic signaling cascades causes loss of trophic factor dependence during neuronal maturation

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Nerve growth factor regulates sympathetic ganglion cell morphology and survival in the adult mouse

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Bax deficiency prevents the increased cell death of immature neurons in bcl-x-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Trophic support promotes survival of bcl-x-deficient telencephalic cells in vitro

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Caspases - controlling intracellular signals by protease zymogen activation

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

1 reference

7 January 2021

Apoptosis in the pathogenesis and treatment of disease

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

The contrasting roles of ICE family proteases and interleukin-1beta in apoptosis induced by trophic factor withdrawal and by copper/zinc superoxide dismutase down-regulation

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Phosphatidylinositol 3-kinase is required for the trophic, but not the survival-promoting, actions of NGF on sympathetic neurons

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Depolarization and neurotrophins converge on the phosphatidylinositol 3-kinase-Akt pathway to synergistically regulate neuronal survival

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Comparison between the timing of JNK activation, c-Jun phosphorylation, and onset of death commitment in sympathetic neurones.

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Widespread elimination of naturally occurring neuronal death in Bax-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

The effects of nerve growth factor and its antiserum on the postnatal development and survival after injury of sensory neurons in rat dorsal root ganglia

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

https://api.crossref.org/works/10.1016/S0896-6273(01)00238-0

7 January 2021