A role for Hsc70 in regulating nucleocytoplasmic transport of a temperature-sensitive p53 (p53Val-135) (Q28211719)

https://api.crossref.org/works/10.1074/JBC.M100200200

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

p53 regulation by post-translational modification and nuclear retention in response to diverse stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Cancer. p53, guardian of the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Tumor suppressor p53: analysis of wild-type and mutant p53 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Amplification of a gene encoding a p53-associated protein in human sarcomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

The tumor suppressor p53 is subject to both nuclear import and export, and both are fast, energy-dependent and lectin-inhibited

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Nuclear exclusion of p53 in a subset of tumors requires MDM2 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Conformational phenotype of p53 is linked to nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Immunological evidence for the association of p53 with a heat shock protein, hsc70, in p53-plus-ras-transformed cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

CRM1 is an export receptor for leucine-rich nuclear export signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

CRM1 is responsible for intracellular transport mediated by the nuclear export signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

The Physical Association of Multiple Molecular Chaperone Proteins with Mutant p53 Is Altered by Geldanamycin, an hsp90-Binding Agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

The nuclear pore‐targeting complex binds to nuclear pores after association with a karyophile

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Antibodies against 70-kD heat shock cognate protein inhibit mediated nuclear import of karyophilic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

An intact HDM2 RING-finger domain is required for nuclear exclusion of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

The MDM2 RING-finger domain is required to promote p53 nuclear export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Cooperation of a single lysine mutation and a C-terminal domain in the cytoplasmic sequestration of the p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

A bipartite nuclear localization signal is required for p53 nuclear import regulated by a carboxyl-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Nucleocytoplasmic transport: signals, mechanisms and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Transport of proteins and RNAs in and out of the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Temperature-dependent switching between "wild-type" and "mutant" forms of p53-Val135.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Cytoplasmically sequestered wild-type p53 protein in neuroblastoma is relocated to the nucleus by a C-terminal peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Specific interaction between the p53 cellular tumour antigen and major heat shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Heat shock protein 84 forms a complex with mutant p53 protein predominantly within a cytoplasmic compartment of the cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Cytoplasmic retention of mutant tsp53 is dependent on an intermediate filament protein (vimentin) scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Protein folding in vivo: the importance of molecular chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Inactivation of tumor suppressor p53 by mot-2, a hsp70 family member.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Functional inactivation but not structural mutation of p53 causes liver cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Nuclear Exclusion of Wild-Type p53 in Immortalized Human Retinoblastoma Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Cellular accumulation of p53 protein: an independent prognostic factor in stage II breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074/JBC.M100200200

Leptomycins A and B, new antifungal antibiotics. I. Taxonomy of the producing strain and their fermentation, purification and characterization.

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.36.639

Identifiers

DOI

10.1074/JBC.M100200200

0 references

Fatcat ID

release_j5hopopcnngkbljt5qdciytvce

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/j5hopopcnngkbljt5qdciytvce