The class II phosphoinositide 3-kinase C2alpha is activated by clathrin and regulates clathrin-mediated membrane trafficking (Q28203805)

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M E Smith

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J Domin

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J H Keen

Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors

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language of work or name

English

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publication date

February 2001

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published in

Molecular Cell

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volume

7

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issue

2

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page(s)

443-9

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cites work

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7 January 2021

Phosphorylation and agonist-specific intracellular trafficking of an epitope-tagged mu-opioid receptor expressed in HEK 293 cells

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7 January 2021

Synergistic activation of dynamin GTPase by Grb2 and phosphoinositides

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7 January 2021

Phosphoinositides in membrane traffic

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7 January 2021

Essential role of phosphoinositide metabolism in synaptic vesicle recycling

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7 January 2021

AP-3: an adaptor-like protein complex with ubiquitous expression

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7 January 2021

Association of the AP-3 adaptor complex with clathrin

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Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin

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7 January 2021

The class II phosphoinositide 3-kinase PI3K-C2alpha is concentrated in the trans-Golgi network and present in clathrin-coated vesicles

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7 January 2021

Epsin binds to clathrin by associating directly with the clathrin-terminal domain. Evidence for cooperative binding through two discrete sites.

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7 January 2021

Phosphoinositide kinases

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Inhibition of calcium-independent mannose 6-phosphate receptor incorporation into trans-Golgi network-derived clathrin-coated vesicles by wortmannin

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7 January 2021

Phosphoinositide-AP-2 interactions required for targeting to plasma membrane clathrin-coated pits

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7 January 2021

A functional phosphatidylinositol 3,4,5-trisphosphate/phosphoinositide binding domain in the clathrin adaptor AP-2 alpha subunit. Implications for the endocytic pathway

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7 January 2021

Arrestin function in G protein-coupled receptor endocytosis requires phosphoinositide binding

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7 January 2021

Spatial control of coated-pit dynamics in living cells

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7 January 2021

Arrestin/clathrin interaction. Localization of the arrestin binding locus to the clathrin terminal domain

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7 January 2021

Regulation of AP-3 function by inositides. Identification of phosphatidylinositol 3,4,5-trisphosphate as a potent ligand

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7 January 2021

Phosphatidylinositol 3-kinase activity is required at a postendocytic step in platelet-derived growth factor receptor trafficking

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7 January 2021

Phosphatidylinositol-4,5-bisphosphate is required for endocytic coated vesicle formation

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7 January 2021

Clathrin assembly proteins: affinity purification and a model for coat assembly

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7 January 2021

Arrestin/clathrin interaction. Localization of the clathrin binding domain of nonvisual arrestins to the carboxy terminus

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7 January 2021

Dominant-negative inhibition of receptor-mediated endocytosis by a dynamin-1 mutant with a defective pleckstrin homology domain.

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7 January 2021

A dominant-negative clathrin mutant differentially affects trafficking of molecules with distinct sorting motifs in the class II major histocompatibility complex (MHC) pathway

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7 January 2021

A family of phosphoinositide 3-kinases in Drosophila identifies a new mediator of signal transduction

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7 January 2021

Wortmannin-sensitive Trafficking Pathways in Chinese Hamster Ovary Cells

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7 January 2021

A presynaptic inositol-5-phosphatase

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7 January 2021

Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain

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7 January 2021

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7 January 2021

Synaptotagmin is an inositol polyphosphate binding protein: isolation and characterization as an Ins 1,3,4,5-P4 binding protein

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7 January 2021

Molecular links between endocytosis and the actin cytoskeleton.

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7 January 2021

Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes

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7 January 2021

The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module

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7 January 2021

Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin

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7 January 2021

A clathrin-binding site in the hinge of the beta 2 chain of mammalian AP-2 complexes.

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7 January 2021

Tandem arrangement of the clathrin and AP-2 binding domains in amphiphysin 1 and disruption of clathrin coat function by amphiphysin fragments comprising these sites

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7 January 2021

Wortmannin alters the transferrin receptor endocytic pathway in vivo and in vitro

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7 January 2021

The CC chemokine monocyte chemotactic peptide-1 activates both the class I p85/p110 phosphatidylinositol 3-kinase and the class II PI3K-C2alpha.

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7 January 2021

Importance of the pleckstrin homology domain of dynamin in clathrin-mediated endocytosis

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7 January 2021

Signaling by distinct classes of phosphoinositide 3-kinases

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7 January 2021

Mouse p170 is a novel phosphatidylinositol 3-kinase containing a C2 domain

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7 January 2021

The role of ADP-ribosylation factor and phospholipase D in adaptor recruitment

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7 January 2021

Ultrastructural immunocytochemical localization of clathrin in cultured fibroblasts

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7 January 2021

Synaptojanin is the major constitutively active phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase in rodent brain.

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7 January 2021

Identification of the Binding Site for Acidic Phospholipids on the PH Domain of Dynamin: Implications for Stimulation of GTPase Activity

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7 January 2021