Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan (Q28203572)

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7 November 2019

title

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan (English)

1 reference

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7 November 2019

main subject

Saccharomyces cerevisiae

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1 reference

4

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7 November 2019

David A. Sinclair

12

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7 November 2019

author name string

Konrad T Howitz

1

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7 November 2019

Kevin J Bitterman

2

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7 November 2019

Haim Y Cohen

3

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7 November 2019

Siva Lavu

5

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7 November 2019

Jason G Wood

6

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7 November 2019

Robert E Zipkin

7

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7 November 2019

Phuong Chung

8

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7 November 2019

Anne Kisielewski

9

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7 November 2019

Li-Li Zhang

10

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7 November 2019

Brandy Scherer

11

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7 November 2019

language of work or name

English

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publication date

24 August 2003

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7 November 2019

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7 November 2019

volume

425

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7 November 2019

issue

6954

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7 November 2019

page(s)

191-196

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Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

7 November 2019

cites work

1 reference

7 January 2021

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

1 reference

7 January 2021

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

1 reference

7 January 2021

A phylogenetically conserved NAD -dependent protein deacetylase activity in the Sir2 protein family.

1 reference

7 January 2021

Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose

1 reference

7 January 2021

An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing

1 reference

7 January 2021

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

1 reference

7 January 2021

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

1 reference

7 January 2021

Negative control of p53 by Sir2alpha promotes cell survival under stress

1 reference

7 January 2021

Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

1 reference

7 January 2021

A conserved regulatory system for aging

1 reference

7 January 2021

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

1 reference

7 January 2021

Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1

1 reference

7 January 2021

Caloric restriction and aging: an update

1 reference

7 January 2021

Quercetin inhibits tyrosine phosphorylation by the cyclic nucleotide-independent, transforming protein kinase, pp60src

1 reference

7 January 2021

Role of plant polyphenols in genomic stability

1 reference

7 January 2021

Cancer chemopreventive activity of resveratrol, a natural product derived from grapes

1 reference

7 January 2021

Efficiency and mechanism of the antioxidant action of trans-resveratrol and its analogues in the radical liposome oxidation

1 reference

7 January 2021

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

1 reference

7 January 2021

Paradigms and pitfalls of yeast longevity research

1 reference

7 January 2021

Extrachromosomal rDNA circles--a cause of aging in yeast

1 reference

7 January 2021

Elimination of replication block protein Fob1 extends the life span of yeast mother cells.

1 reference

7 January 2021

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

1 reference

7 January 2021

Metabolic control and gene dysregulation in yeast aging

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7 January 2021

Molecular mechanism of the chemopreventive effect of resveratrol

1 reference

7 January 2021

Anti-apoptotic effect of trans-resveratrol on paclitaxel-induced apoptosis in the human neuroblastoma SH-SY5Y cell line

1 reference

7 January 2021

Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes.

1 reference

7 January 2021

Resveratrol: a molecule whose time has come? And gone?

1 reference

7 January 2021

Identifiers

DOI

10.1038/NATURE01960

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12939617 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 November 2019

1037301833

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017