Structural and functional organization of the animal fatty acid synthase (Q28190255)

title

Structural and functional organization of the animal fatty acid synthase (English)

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23 December 2023

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23 December 2023

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23 December 2023

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Andrzej Witkowski

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23 December 2023

author name string

Stuart Smith

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Anil K. Joshi

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full work available at URL

23 December 2023

language of work or name

English

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publication date

July 2003

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https://api.elsevier.com/content/article/PII:S016378270200067X?httpAccept=text/xml

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23 December 2023

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Progress in Lipid Research

23 December 2023

published in

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volume

42

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issue

4

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page(s)

289-317

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cites work

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2-MERCAPTOETHYLAMINE AND BETA-ALANINE AS COMPONENTS OF ACYL CARRIER PROTEIN.

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ACYL CARRIER PROTEIN. IV. THE IDENTIFICATION OF 4'-PHOSPHOPANTETHEINE AS THE PROSTHETIC GROUP OF THE ACYL CARRIER PROTEIN

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ACYL-CARRIER PROTEIN. II. INTERMEDIARY REACTIONS OF FATTY ACID SYNTHESIS

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Mechanism of dissociation of pigeon liver fatty acid synthetase complex into half-molecular weight subunits and their reassociation to enzymatically active complex

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Sodium dodecyl sulfate disc-gel electrophoresis pattern of protease-free chicken liver fatty acid synthetase

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Regulation of synthesis of hepatic fatty acid synthetase: binding of fatty acid synthetase antibodies to polysomes

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Presence of two polypeptide chains comprising fatty acid synthetase

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Temperature-Sensitive Mutants of the Yeast Fatty-Acid-Synthetase Complex

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Separation of two active forms (holo-a and holo-b) of pigeon liver fatty acid synthetase and their interconversion by phosphorylation and dephosphorylation

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Subunits of fatty acid synthetase complexes. Comparative study of enzyme activities and properties of the half-molecular weight nonidentical subunits of fatty acid synthetase complexes obtained from rat, human, and chicken liver and yeast

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Biosynthesis and structure of the yeast fatty acid synthetase complex

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beta-Ketoacyl-ACP synthase I of Escherichia coli: nucleotide sequence of the fabB gene and identification of the cerulenin binding residue.

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The pentafunctional FAS1 gene of yeast: its nucleotide sequence and order of the catalytic domains.

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Rat mammary gland fatty acid synthase: localization of the constituent domains and two functional polyadenylation/termination signals in the cDNA

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Molecular cloning and sequencing of cDNAs encoding the entire rat fatty acid synthase

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Molecular cloning and sequencing of chicken liver fatty acid synthase cDNA.

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Structures of beta-ketoacyl-acyl carrier protein synthase I complexed with fatty acids elucidate its catalytic machinery

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Crystal structure of beta-ketoacyl-acyl carrier protein synthase II from E.coli reveals the molecular architecture of condensing enzymes

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Crystal structure of beta-ketoacyl-acyl carrier protein synthase III. A key condensing enzyme in bacterial fatty acid biosynthesis

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The 1.8 A crystal structure and active-site architecture of beta-ketoacyl-acyl carrier protein synthase III (FabH) from escherichia coli

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Three-dimensional structure of acyl carrier protein in solution determined by nuclear magnetic resonance and the combined use of dynamical simulated annealing and distance geometry.

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The Escherichia coli malonyl-CoA:acyl carrier protein transacylase at 1.5-A resolution. Crystal structure of a fatty acid synthase component

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A mechanism of drug action revealed by structural studies of enoyl reductase

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Structure of a dehydratase-isomerase from the bacterial pathway for biosynthesis of unsaturated fatty acids: two catalytic activities in one active site

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7 January 2021

Structure of beta-ketoacyl-[acyl carrier protein] reductase from Escherichia coli: negative cooperativity and its structural basis

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7 January 2021

Structure of fatty acid synthetase from the Harderian gland of guinea pig. Proteolytic dissection and electron microscopic studies

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7 January 2021

Structure-function relationships of the Saccharomyces cerevisiae fatty acid synthase. Three-dimensional structure

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7 January 2021

Quaternary structure of human fatty acid synthase by electron cryomicroscopy

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7 January 2021

Construction of a cDNA encoding the multifunctional animal fatty acid synthase and expression in Spodoptera frugiperda cells using baculoviral vectors

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7 January 2021

Heterologously expressed acyl carrier protein domain of rat fatty acid synthase functions in Escherichia coli fatty acid synthase and Streptomyces coelicolor polyketide synthase systems

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7 January 2021

Cloning and expression of the multifunctional human fatty acid synthase and its subdomains in Escherichia coli

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The Biosynthesis of Long-Chain Fatty Acids. Stereochemical Differentiation in the Enzymic Incorporation of Chiral Acetates

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7 January 2021

Stereochemistry of the reactions catalyzed by chicken liver fatty acid synthase

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Fatty acid synthase, a proficient multifunctional enzyme

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The animal fatty acid synthase: one gene, one polypeptide, seven enzymes

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Expression in Escherichia coli and refolding of the malonyl-/acetyltransferase domain of the multifunctional animal fatty acid synthase.

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7 January 2021

Characterization of the malonyl-/acetyltransacylase domain of the multifunctional animal fatty acid synthase by expression in Escherichia coli and refolding in vitro

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7 January 2021

Amino acid sequence around the active-site serine residue in the acyltransferase domain of goat mammary fatty acid synthetase

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7 January 2021

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Alteration of the substrate specificity of the malonyl-CoA/acetyl-CoA:acyl carrier protein S-acyltransferase domain of the multifunctional fatty acid synthase by mutation of a single arginine residue

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7 January 2021

Specific modification of the condensation domain of fatty acid synthase and the determination of the primary structure of the modified active site peptides

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7 January 2021

Mapping of functional interactions between domains of the animal fatty acid synthase by mutant complementation in vitro

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7 January 2021

Characterization of the Interthiol Acyltransferase Reaction Catalyzed by the β-Ketoacyl Synthase Domain of the Animal Fatty Acid Synthase

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7 January 2021

Distribution of reaction intermediates on chicken liver fatty acid synthase

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7 January 2021

beta-Ketoacyl-[acyl carrier protein] synthase I of Escherichia coli: aspects of the condensation mechanism revealed by analyses of mutations in the active site pocket

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7 January 2021

Mechanism of the beta-ketoacyl synthase reaction catalyzed by the animal fatty acid synthase

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7 January 2021

The crystal structure of beta-ketoacyl-acyl carrier protein synthase II from Synechocystis sp. at 1.54 A resolution and its relationship to other condensing enzymes

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7 January 2021

Conversion of a beta-ketoacyl synthase to a malonyl decarboxylase by replacement of the active-site cysteine with glutamine

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7 January 2021

Reaction of Yeast Fatty Acid Synthetase with Iodoacetamide. 3. Malonyl-Coenzyme A Decarboxylase as Product of the Reaction of Fatty Acid Synthetase with Iodoacetamide

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7 January 2021

Mapping the functional topology of the animal fatty acid synthase by mutant complementation in vitro

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7 January 2021

Redesign of the coenzyme specificity of a dehydrogenase by protein engineering

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7 January 2021

Transacylation as a chain-termination mechanism in fatty acid synthesis by mammalian fatty acid synthetase. Synthesis of butyrate and hexanoate by lactating cow mammary gland fatty acid synthetase

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7 January 2021

Specific release of the thioesterase component of the fatty acid synthetase multienzyme complex by limited trypsinization

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7 January 2021

The X-ray crystal structure of beta-ketoacyl [acyl carrier protein] synthase I

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7 January 2021

Correlation of enzymatic activities and aggregation state in chicken liver fatty acid synthase

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7 January 2021

Characterization of fatty acid synthase monomers restrained from reassociating by immobilization to a solid support

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7 January 2021

Release of two thioesterase domains from fatty acid synthetase by limited digestion with trypsin

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7 January 2021

Structural organization of the multifunctional animal fatty-acid synthase

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Human fatty acid synthase: role of interdomain in the formation of catalytically active synthase dimer

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7 January 2021

Mammalian fatty acid synthetase is a structurally and functionally symmetrical dimer

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7 January 2021

The Malonyl/Acetyltransferase and β-Ketoacyl Synthase Domains of the Animal Fatty Acid Synthase Can Cooperate with the Acyl Carrier Protein Domain of Either Subunit

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7 January 2021

Differential Affinity Labeling of the Two Subunits of the Homodimeric Animal Fatty Acid Synthase Allows Isolation of Heterodimers Consisting of Subunits That Have Been Independently Modified

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Fatty acid synthase dimers containing catalytically active beta-ketoacyl synthase or malonyl/acetyltransferase domains in only one subunit can support fatty acid synthesis at the acyl carrier protein domains of both subunits

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7 January 2021

Dibromopropanone cross-linking of the phosphopantetheine and active-site cysteine thiols of the animal fatty acid synthase can occur both inter- and intrasubunit. Reevaluation of the side-by-side, antiparallel subunit model

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7 January 2021

Fatty acid synthase: in vitro complementation of inactive mutants

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7 January 2021

Specificity and site of action of a mammary gland thioesterase which releases acyl moieties from thioester linkage to the fatty acid synthetase

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7 January 2021

Purification and some properties of a medium-chain acyl-thioester hydrolase from lactating-rabbit mammary gland which terminates chain elongation in fatty acid synthesis

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7 January 2021

Involvement of a thioesterase in the production of short-chain fatty acids in the uropygial glands of mallard ducks (Anas platyrhynchos)

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7 January 2021

Human fatty acid synthase: Assembling recombinant halves of the fatty acid synthase subunit protein reconstitutes enzyme activity

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7 January 2021

Purification and properties of fatty acid synthetase from a human breast cell line

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7 January 2021

Expression in Escherichia coli, purification and characterization of two mammalian thioesterases involved in fatty acid synthesis

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Derived amino acid sequence and identification of active site residues of Escherichia coli beta-hydroxydecanoyl thioester dehydrase

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Site-directed mutagenesis studies on the recombinant thioesterase domain of chicken fatty acid synthase expressed in Escherichia coli

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Identifiers

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017