A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage (Q28144576)

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E P Rogakou

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V Yamazaki

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C U Kirchgessner

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M Gellert

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W M Bonner

hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks

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language of work or name

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issue

15

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page(s)

886-95

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cites work

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7 January 2021

Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes

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Localization and dynamic relocalization of mammalian Rad52 during the cell cycle and in response to DNA damage

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Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

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7 January 2021

Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage

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7 January 2021

Altered regulation of cyclin G in human breast cancer and its specific localization at replication foci in response to DNA damage in p53 / cells.

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7 January 2021

In situ visualization of DNA double-strand break repair in human fibroblasts

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7 January 2021

A genetic study of x-ray sensitive mutants in yeast

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7 January 2021

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

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7 January 2021

Alteration of telomeric sequences and senescence caused by mutations in RAD50 of Saccharomyces cerevisiae

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7 January 2021

Telomere maintenance is dependent on activities required for end repair of double-strand breaks

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7 January 2021

Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae

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7 January 2021

The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae

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7 January 2021

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

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7 January 2021

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

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7 January 2021

Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95

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7 January 2021

Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response

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7 January 2021

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

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7 January 2021

Megabase chromatin domains involved in DNA double-strand breaks in vivo

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7 January 2021

The DNA-dependent protein kinase

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7 January 2021

c-Jun is phosphorylated by the DNA-dependent protein kinase in vitro; definition of the minimal kinase recognition motif

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7 January 2021

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

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7 January 2021

When is a lipid kinase not a lipid kinase? When it is a protein kinase

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7 January 2021

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

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7 January 2021

A phosphatidylinositol 3-kinase inhibitor wortmannin induces radioresistant DNA synthesis and sensitizes cells to bleomycin and ionizing radiation

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7 January 2021

Wortmannin inhibits repair of DNA double-strand breaks in irradiated normal human cells.

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7 January 2021

Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

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7 January 2021

Complementation of the radiosensitive M059J cell line

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7 January 2021

Characterization of ATM expression, localization, and associated DNA-dependent protein kinase activity

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7 January 2021

Lack of correlation between ATM protein expression and tumour cell radiosensitivity

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7 January 2021

Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart

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7 January 2021

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

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7 January 2021

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

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7 January 2021

Initial events in the cellular effects of ionizing radiations: clustered damage in DNA.

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7 January 2021

The role of DNA double strand breaks in lonizing radiation-induced killing of eukaryotic cells

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7 January 2021

Saturation of a DNA repair process in dividing and nondividing mammalian cells.

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7 January 2021

Kinetics of DNA Double-strand Break Repair Throughout the Cell Cycle as Assayed by Pulsed Field Gel Electrophoresis in CHO Cells

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7 January 2021

Saturated and unsaturated repair of DNA strand breaks in CHO cells after X-irradiation with doses ranging from 3 to 90 Gy.

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7 January 2021

A component of DNA double-strand break repair is dependent on the spatial orientation of the lesions within the higher-order structures of chromatin

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7 January 2021

Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family

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7 January 2021

Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways

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7 January 2021

Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae

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7 January 2021

TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1

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7 January 2021

Extended C-terminal tail of wheat histone H2A interacts with DNA of the "linker" region.

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7 January 2021

Histone 1 is proximal to histone 2A and to A24.

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7 January 2021

Use of an immobilized enzyme and specific antibodies to analyse the accessibility and role of histone tails in chromatin structure

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7 January 2021

10.1016/S0960-9822(00)00610-2

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

10959836

1 reference

Consolidated OpenCitations Corpus – April 2017