Analysis of vertebrate SCL loci identifies conserved enhancers (Q28143951)

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L M Barton

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J G Gilbert

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A J Bench

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M J Sanchez

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S Bahn

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S Mistry

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D Grafham

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A McMurray

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M Vaudin

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E Amaya

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D R Bentley

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A R Green

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A M Sinclair

Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx

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language of work or name

English

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publication date

February 2000

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published in

Nature Biotechnology

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volume

18

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issue

2

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page(s)

181-6

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cites work

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Detecting conserved regulatory elements with the model genome of the Japanese puffer fish, Fugu rubripes

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The conserved role of Krox-20 in directing Hox gene expression during vertebrate hindbrain segmentation.

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Large-scale comparative sequence analysis of the human and murine Bruton's tyrosine kinase loci reveals conserved regulatory domains

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Genomic sequence comparison of the human and mouse XRCC1 DNA repair gene regions

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Sequence analysis of the ERCC2 gene regions in human, mouse, and hamster reveals three linked genes

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Locus control regions of mammalian beta-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights

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Unsuspected role for the T-cell leukemia protein SCL/tal-1 in vascular development

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The SCL gene specifies haemangioblast development from early mesoderm.

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TAL1/SCL Is Expressed in Endothelial Progenitor Cells/Angioblasts and Defines a Dorsal-to-Ventral Gradient of Vasculogenesis

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Distinct 5' SCL enhancers direct transcription to developing brain, spinal cord, and endothelium: neural expression is mediated by GATA factor binding sites

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Distinct mechanisms direct SCL/tal-1 expression in erythroid cells and CD34 positive primitive myeloid cells

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Transcriptional regulation of the stem cell leukemia gene by PU.1 and Elf-1.

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Transcription of the SCL gene in erythroid and CD34 positive primitive myeloid cells is controlled by a complex network of lineage-restricted chromatin-dependent and chromatin-independent regulatory elements.

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The SCL gene is formed from a transcriptionally complex locus

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Structure of the gene encoding the murine SCL protein

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DIALIGN: finding local similarities by multiple sequence alignment

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A dot-matrix program with dynamic threshold control suited for genomic DNA and protein sequence analysis

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Characterization of a polypyrimidine/polypurine tract in the promoter of the gene for chicken malic enzyme

21 January 2018

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The upstream sequence element of the C2 complement poly(A) signal activates mRNA 3' end formation by two distinct mechanisms.

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Searching for regulatory elements in human noncoding sequences.

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The pufferfish SLP-1 gene, a new member of the SCL/TAL-1 family of transcription factors.

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Basic local alignment search tool

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MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

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Long Human–Mouse Sequence Alignments Reveal Novel Regulatory Elements: A Reason to Sequence the Mouse Genome

21 January 2018

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7 January 2021

The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages

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7 January 2021

The scl gene product is required for the generation of all hematopoietic lineages in the adult mouse

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7 January 2021

Definition of an efficient synthetic poly(A) site

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7 January 2021

Upstream sequence elements enhance poly(A) site efficiency of the C2 complement gene and are phylogenetically conserved

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7 January 2021