Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formation (Q28139699)

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M Nogami

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T Yokozeki

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M Yamazaki

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H Nakamura

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H Watanabe

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K Kawamoto

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K Nakayama

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A J Morris

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M A Frohman

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Y Kanaho

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

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language of work or name

English

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publication date

24 November 1999

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published in

Cell

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volume

99

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issue

5

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page(s)

521-32

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cites work

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Inositol trisphosphate, a novel second messenger in cellular signal transduction

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Phospholipase D and cell signaling

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

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The sequence of phosphatidylinositol-4-phosphate 5-kinase defines a novel family of lipid kinases

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ADP-ribosylation factor, a small GTP-dependent regulatory protein, stimulates phospholipase D activity

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Oncogenes and signal transduction

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A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase

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The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells

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Catalytic properties of a purified phosphatidylinositol-4-phosphate kinase from rat brain

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Phospholipase D: a downstream effector of ARF in granulocytes

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Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization

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Complementation of growth factor receptor-dependent mitogenic signaling by a truncated type I phosphatidylinositol 4-phosphate 5-kinase.

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The cloning and sequence of the C isoform of PtdIns4P 5-kinase

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A role for POR1, a Rac1-interacting protein, in ARF6-mediated cytoskeletal rearrangements

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Protein N-myristoylation in Escherichia coli: reconstitution of a eukaryotic protein modification in bacteria

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ARF and PITP restore GTPγS-stimulated protein secretion from cytosol-depleted HL60 cells by promoting PIP2 synthesis

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EFA6, a sec7 domain-containing exchange factor for ARF6, coordinates membrane recycling and actin cytoskeleton organization

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Real-time visualization of PH domain-dependent translocation of phospholipase C-delta1 in renal epithelial cells (MDCK): response to hypo-osmotic stress

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Requirement of phosphatidylinositol 4,5-bisphosphate for alpha-actinin function

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ARF mediates recruitment of PtdIns-4-OH kinase-beta and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complex

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Human ADP-ribosylation factor-activated phosphatidylcholine-specific phospholipase D defines a new and highly conserved gene family

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Characterization of two alternately spliced forms of phospholipase D1. Activation of the purified enzymes by phosphatidylinositol 4,5-bisphosphate, ADP-ribosylation factor, and Rho family monomeric GTP-binding proteins and protein kinase C-alpha

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Thrombin receptor ligation and activated rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets

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ATP-dependent inositide phosphorylation required for Ca2 -activated secretion

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Structure and intracellular localization of mouse ADP-ribosylation factors type 1 to type 6 (ARF1-ARF6)

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Cloning of cDNAs encoding two isoforms of 68-kDa type I phosphatidylinositol-4-phosphate 5-kinase

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Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family

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A novel phosphatidylinositol-5-phosphate 4-kinase (phosphatidylinositol-phosphate kinase IIgamma) is phosphorylated in the endoplasmic reticulum in response to mitogenic signals

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Modulation of gelsolin function by phosphatidylinositol 4,5-bisphosphate

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Specific interaction between phosphatidylinositol 4,5-bisphosphate and profilactin

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Comparative activity of ADP-ribosylation factor family members in the early steps of coated vesicle formation on rat liver Golgi membranes

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Type I phosphatidylinositol-4-phosphate 5-kinases are distinct members of this novel lipid kinase family

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Production and characterization of monoclonal antibodies that bind to phosphatidylinositol 4,5-bisphosphate

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Aluminum fluoride stimulates surface protrusions in cells overexpressing the ARF6 GTPase

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A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

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Inhibition of receptor signaling to phospholipase D by Clostridium difficile toxin B. Role of Rho proteins

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PLD2 complexes with the EGF receptor and undergoes tyrosine phosphorylation at a single site upon agonist stimulation

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Rho Family GTPases Bind to Phosphoinositide Kinases

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Characterization of a Rac1- and RhoGDI-associated lipid kinase signaling complex

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Cytotoxicity of brefeldin A correlates with its inhibitory effect on membrane binding of COP coat proteins

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Stimulation of phosphatidylinositol 4-phosphate phosphorylation in human placenta membranes by GTP gamma S

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A small G-protein involved in phosphatidylinositol-4-phosphate kinase activation

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Visualization of phosphoinositides that bind pleckstrin homology domains: calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide pools

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Interaction of the small G protein RhoA with the C terminus of human phospholipase D1

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