The expression of Jagged1 in the developing mammalian heart correlates with cardiovascular disease in Alagille syndrome (Q28137728)

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J Morabito

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S Gottlieb

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D A Piccoli

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N B Spinner

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H S Baldwin

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R J Oakey

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

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language of work or name

English

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publication date

December 1999

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published in

Human Molecular Genetics

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volume

8

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issue

13

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page(s)

2443-9

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cites work

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Mutations in the human Jagged1 gene are responsible for Alagille syndrome

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TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

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Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

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Features of Alagille syndrome in 92 patients: frequency and relation to prognosis

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Syndromic paucity of interlobular bile ducts (Alagille syndrome or arteriohepatic dysplasia): review of 80 cases

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Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development

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Jagged: A mammalian ligand that activates notch1

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Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule

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Molecular regulation of atrioventricular valvuloseptal morphogenesis

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Expression patterns of Notch1, Serrate1, Serrate2 and Delta1 in tissues of the developing chick limb.

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Notch1 is essential for postimplantation development in mice.

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A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis

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Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1

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Common epicardial origin of coronary vascular smooth muscle, perivascular fibroblasts, and intermyocardial fibroblasts in the avian heart

21 January 2018

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Blood vessel formation: what is its molecular basis?

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Genetic analysis of blood vessel formation role of endothelial versus smooth muscle cells

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An antisense oligonucleotide to the notch ligand jagged enhances fibroblast growth factor-induced angiogenesis in vitro

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1 reference

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