Fragile X mental retardation protein FMRP binds mRNAs in the nucleus (Q28119156)

4 January 2017

title

Fragile X mental retardation protein FMRP binds mRNAs in the nucleus (English)

1 reference

FMRP translational regulator 1

4 January 2017

main subject

1 reference

GOA release 2020-03-11

3

Stephanie Ceman

1 reference

4 January 2017

Miri Kim

1

1 reference

4 January 2017

Michel Bellini

series ordinal

2

1 reference

4 January 2017

language of work or name

English

0 references

publication date

1 January 2009

1 reference

Molecular and Cellular Biology

4 January 2017

published in

1 reference

4 January 2017

volume

29

1 reference

4 January 2017

issue

1

1 reference

4 January 2017

page(s)

214–228

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Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm

4 January 2017

cites work

1 reference

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20 March 2017

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20 March 2017

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20 March 2017

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Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them

20 March 2017

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Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes

20 March 2017

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FMRP Associates with Polyribosomes as an mRNP, and the I304N Mutation of Severe Fragile X Syndrome Abolishes This Association

20 March 2017

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The protein product of the fragile X gene, FMR1, has characteristics of an RNA-binding protein

20 March 2017

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The G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancer

20 March 2017

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Drosophila Y14 shuttles to the posterior of the oocyte and is required for oskar mRNA transport

20 March 2017

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20 March 2017

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Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations

20 March 2017

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20 March 2017

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The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif

20 March 2017

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TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus

20 March 2017

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20 March 2017

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Variation of the CGG repeat at the fragile X site results in genetic instability: Resolution of the Sherman paradox

20 March 2017

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Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

20 March 2017

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The fragile X mental retardation protein is a molecular adaptor between the neurospecific KIF3C kinesin and dendritic RNA granules

20 March 2017

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The fragile X mental retardation protein interacts with a distinct mRNA nuclear export factor NXF2

20 March 2017

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Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses

20 March 2017

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Transport of fragile X mental retardation protein via granules in neurites of PC12 cells

20 March 2017

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REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export.

20 March 2017

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Dissecting FMR1, the protein responsible for fragile X syndrome, in its structural and functional domains

20 March 2017

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The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences

20 March 2017

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CRM1 is responsible for intracellular transport mediated by the nuclear export signal

20 March 2017

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A short amino acid sequence able to specify nuclear location

7 April 2017

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7 April 2017

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Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function

7 April 2017

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Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome

7 April 2017

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The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay

7 April 2017

1 reference

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Transport of proteins and RNAs in and out of the nucleus

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

Evidence for a role of CRM1 in signal-mediated nuclear protein export

7 April 2017

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Sequence requirements for nuclear location of simian virus 40 large-T antigen

7 April 2017

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Formation of a Tap/NXF1 homotypic complex is mediated through the amino-terminal domain of Tap and enhances interaction with nucleoporins

7 April 2017

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Splicing-independent recruitment of spliceosomal small nuclear RNPs to nascent RNA polymerase II transcripts

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

Fragile X mental retardation protein FMRP and the RNA export factor NXF2 associate with and destabilize Nxf1 mRNA in neuronal cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

The tripartite motif of nuclear factor 7 is required for its association with transcriptional units

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

Fragile X mental retardation protein controls trailer hitch expression and cleavage furrow formation in Drosophila embryos

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

An intron with a constitutive transport element is retained in a Tap messenger RNA.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

Dynamic nuclear pore complexes: life on the edge.

29 September 2017

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The Wilms' tumor 1 (WT1) gene ( KTS isoform) functions with a CTE to enhance translation from an unspliced RNA with a retained intron

29 September 2017

1 reference

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Transcription, translation and fragile X syndrome

29 September 2017

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Identification and characterization of the methyl arginines in the fragile X mental retardation protein Fmrp

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

Mutations in tap uncouple RNA export activity from translocation through the nuclear pore complex

29 September 2017

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Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1.

29 September 2017

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SRprises along a messenger's journey

29 September 2017

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Tap and NXT promote translation of unspliced mRNA.

29 September 2017

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A novel family of nuclear transport receptors mediates the export of messenger RNA to the cytoplasm

29 September 2017

1 reference

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The nuclear connection in RNA transport and localization

29 September 2017

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Trapping of messenger RNA by Fragile X Mental Retardation protein into cytoplasmic granules induces translation repression

29 September 2017

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Lampbrush chromosomes and associated bodies: new insights into principles of nuclear structure and function

29 September 2017

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Reversible cross-linking combined with immunoprecipitation to study RNA-protein interactions in vivo

29 September 2017

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Dynamic imaging of endoplasmic reticulum Ca2 concentration in insulin-secreting MIN6 Cells using recombinant targeted cameleons: roles of sarco(endo)plasmic reticulum Ca2 -ATPase (SERCA)-2 and ryanodine receptors

29 September 2017

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Small bristles, the Drosophila ortholog of NXF-1, is essential for mRNA export throughout development

29 September 2017

1 reference

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Nucleocytoplasmic transport enters the atomic age.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

A nuclear role for the Fragile X mental retardation protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

Alternative splicing of exon 14 determines nuclear or cytoplasmic localisation of fmr1 protein isoforms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

Fine structure of the human FMR1 gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

High resolution methylation analysis of the FMR1 gene trinucleotide repeat region in fragile X syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

A major developmental transition in early xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage

29 September 2017

1 reference

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Dissection of a nuclear localization signal

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

Analysis of domains affecting intracellular localization of the FMRP protein.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

The molecular basis of fragile X syndrome

2 June 2018

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A point mutation in the FMR-1 gene associated with fragile X mental retardation

2 June 2018

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Polarization of both major body axes in Drosophila by gurken-torpedo signalling

2 June 2018

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Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

DNA methylation represses FMR-1 transcription in fragile X syndrome

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

Fragile X mental retardation protein (FMRP) binds specifically to the brain cytoplasmic RNAs BC1/BC200 via a novel RNA-binding motif

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

Two members of the Fxr gene family, Fmr1 and Fxr1, are differentially expressed in Xenopus tropicalis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

Characterisation of Fmrp in zebrafish: evolutionary dynamics of the fmr1 gene

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

The N-terminus of the fragile X mental retardation protein contains a novel domain involved in dimerization and RNA binding.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

SR splicing factors serve as adapter proteins for TAP-dependent mRNA export

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

Development and characterization of antibodies that immunoprecipitate the FMR1 protein

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

Binding and internalization of fluorescent opioid peptide conjugates in living cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

Human and murine FMR-1: alternative splicing and translational initiation downstream of the CGG-repeat

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2612477

The fragile X mental retardation protein is a ribonucleoprotein containing both nuclear localization and nuclear export signals

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/18936162