Concordant analysis of KRAS, BRAF, PIK3CA mutations, and PTEN expression between primary colorectal cancer and matched metastases (Q28088489)

phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase

2 August 2019

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20 November 2019

phosphatidylinositol 3-kinases

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18 December 2019

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Chen Mao

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Xin-Yin Wu

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Zu-Yao Yang

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Diane Erin Threapleton

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Jin-Qiu Yuan

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Yuan-Yuan Yu

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Jin-Ling Tang

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language of work or name

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2 February 2015

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page(s)

8065

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Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International

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21 March 2019

3 April 2019

2 August 2019

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on focus list of Wikimedia project

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ScienceSource

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cites work

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PTEN expression is consistent in colorectal cancer primaries and metastases and associates with patient survival

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KRAS mutations in primary tumours and post-FOLFOX metastatic lesions in cases of colorectal cancer

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KRAS mutations in primary colorectal cancer tumors and related metastases: a potential role in prediction of lung metastasis

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Molecular changes in the Ki-ras and APC genes in primary colorectal carcinoma and synchronous metastases compared with the findings in accompanying adenomas

29 September 2017

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Molecular staging of colorectal cancer: K-ras mutation analysis of lymph nodes upstages Dukes B patients

29 September 2017

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Stability of K-ras mutations throughout the natural history of human colorectal cancer

29 September 2017

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K-ras point mutations in human colorectal carcinomas: relation to aneuploidy and metastasis

2 June 2018

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21 January 2018

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K-Ras mutations and treatment outcome in colorectal cancer patients receiving exclusive fluoropyrimidine therapy.

21 January 2018

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Heterogeneity within and between primary colorectal carcinomas and matched metastases as revealed by analysis of Ki-ras and p53 mutations.

21 January 2018

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Analysis of KRAS, BRAF, PTEN, IGF1R, EGFR intron 1 CA status in both primary tumors and paired metastases in determining benefit from cetuximab therapy in colon cancer

21 January 2018

1 reference

Heterogeneity of KRAS status may explain the subset of discordant KRAS status between primary and metastatic colorectal cancer.

21 January 2018

1 reference

Mutation analysis of KRAS in primary colorectal cancer and matched metastases by means of highly sensitivity molecular assay.

21 January 2018

1 reference

Combined analysis of KRAS and PIK3CA mutations, MET and PTEN expression in primary tumors and corresponding metastases in colorectal cancer

21 January 2018

1 reference

PTEN status in advanced colorectal cancer treated with cetuximab.

21 January 2018

1 reference

Analysis of the concordance in the EGFR pathway status between primary tumors and related metastases of colorectal cancer patients:implications for cancer therapy.

21 January 2018

1 reference

PTEN expression and KRAS mutations on primary tumors and metastases in the prediction of benefit from cetuximab plus irinotecan for patients with metastatic colorectal cancer.

21 January 2018

1 reference

Degraded DNA may induce discordance of KRAS status between primary colorectal cancer and corresponding liver metastases.

21 January 2018

1 reference

RAF/RAS oncogenes and mismatch-repair status

21 January 2018

1 reference

KRAS Mutation Is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer

21 January 2018

1 reference

Delineation of the infrequent mosaicism ofKRASmutational status in metastatic colorectal adenocarcinomas

21 January 2018

1 reference

PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients

21 January 2018

1 reference

Sensitive detection of K-ras mutations augments diagnosis of colorectal cancer metastases in the liver

21 January 2018

1 reference

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KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression

27 November 2018

1 reference

Differential activation of ras genes by point mutation in human colon cancer with metastases to either lung or liver

21 January 2018

1 reference

12 December 2020

Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastases

1 reference

12 December 2020

High concordance of KRAS status between primary colorectal tumors and related metastatic sites: implications for clinical practice

1 reference

12 December 2020

Genotypic classification of colorectal adenocarcinoma. Biologic behavior correlates with K-ras-2 mutation type

1 reference

12 December 2020

Acquired KRAS mutations during progression of colorectal cancer metastases: possible implications for therapy and prognosis

1 reference

12 December 2020

High concordance of BRAF status between primary colorectal tumours and related metastatic sites: implications for clinical practice

1 reference

12 December 2020

Concordant analysis of KRAS status in primary colon carcinoma and matched metastasis

1 reference

12 December 2020

Heterogeneity of mutant versus wild-type Ki-ras in primary and metastatic colorectal carcinomas, and association of codon-12 valine with early mortality

1 reference

12 December 2020

Mutations of KRAS and BRAF in primary and matched metastatic sites of colorectal cancer

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12 December 2020

Identifiers

DOI

10.1038/SREP08065

1 reference

Dimensions Publication ID

1050678954

0 references

1 reference

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PubMed publication ID

25639985

1 reference