Concise Review: NANOG in Cancer Stem Cells and Tumor Development: An Update and Outstanding Questions (Q28088370)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821200 AND SRC:MED&resulttype=core&format=json

4 March 2020

review article

1 reference

title

Concise Review: NANOG in Cancer Stem Cells and Tumor Development: An Update and Outstanding Questions (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821200 AND SRC:MED&resulttype=core&format=json

4 March 2020

main subject

neoplastic stem cells

1 reference

Junchen Wang

3

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821200 AND SRC:MED&resulttype=core&format=json

4 March 2020

Collene R Jeter

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821200 AND SRC:MED&resulttype=core&format=json

4 March 2020

Dean G Tang

series ordinal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821200 AND SRC:MED&resulttype=core&format=json

4 March 2020

language of work or name

1 reference

13 May 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821200 AND SRC:MED&resulttype=core&format=json

4 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821200 AND SRC:MED&resulttype=core&format=json

4 March 2020

volume

33

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821200 AND SRC:MED&resulttype=core&format=json

4 March 2020

issue

8

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821200 AND SRC:MED&resulttype=core&format=json

4 March 2020

page(s)

2381-2390

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821200 AND SRC:MED&resulttype=core&format=json

The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration

4 March 2020

cites work

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Nanog1 in NTERA-2 and recombinant NanogP8 from somatic cancer cells adopt multiple protein conformations and migrate at multiple M.W species

20 March 2017

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Lineage-restricted function of the pluripotency factor NANOG in stratified epithelia.

20 March 2017

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Transcription factor heterogeneity in pluripotent stem cells: a stochastic advantage

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MBD3/NuRD facilitates induction of pluripotency in a context-dependent manner

29 September 2017

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On the origin and evolutionary history of NANOG.

29 September 2017

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Activated 5'flanking region of NANOGP8 in a self-renewal environment is associated with increased sphere formation and tumor growth of prostate cancer cells

29 September 2017

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Effect of shRNA-mediated inhibition of Nanog gene expression on the behavior of human gastric cancer cells

29 September 2017

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The cell-cycle state of stem cells determines cell fate propensity.

29 September 2017

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Nanog, a novel prognostic marker for lung cancer

29 September 2017

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Knockdown of Oct4 and Nanog expression inhibits the stemness of pancreatic cancer cells

29 September 2017

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In vivo functional studies of tumor-specific retrogene NanogP8 in transgenic animals

29 September 2017

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Brain tumor stem cell multipotency correlates with nanog expression and extent of passaging in human glioblastoma xenografts

29 September 2017

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The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis

29 September 2017

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Reprogramming activity of NANOGP8, a NANOG family member widely expressed in cancer

29 September 2017

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Enrichment of putative prostate cancer stem cells after androgen deprivation: upregulation of pluripotency transactivators concurs with resistance to androgen deprivation in LNCaP cell lines

29 September 2017

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Resveratrol promotes proteasome-dependent degradation of Nanog via p53 activation and induces differentiation of glioma stem cells

29 September 2017

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NANOG promotes liver cancer cell invasion by inducing epithelial-mesenchymal transition through NODAL/SMAD3 signaling pathway

29 September 2017

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Sox2 cooperates with inflammation-mediated Stat3 activation in the malignant transformation of foregut basal progenitor cells

29 September 2017

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NANOG-dependent function of TET1 and TET2 in establishment of pluripotency

29 September 2017

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Nanog signaling in cancer promotes stem-like phenotype and immune evasion

29 September 2017

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NANOG modulates stemness in human colorectal cancer

29 September 2017

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MicroRNA miR-214 regulates ovarian cancer cell stemness by targeting p53/Nanog

29 September 2017

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Human Nanog pseudogene8 promotes the proliferation of gastrointestinal cancer cells

29 September 2017

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Stem-like cells with luminal progenitor phenotype survive castration in human prostate cancer

29 September 2017

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RNA interference-mediated silencing of NANOG reduces cell proliferation and induces G0/G1 cell cycle arrest in breast cancer cells

29 September 2017

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Cancer vaccination drives Nanog-dependent evolution of tumor cells toward an immune-resistant and stem-like phenotype

29 September 2017

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Retracted: Prostate Cancer Cell Lines under Hypoxia Exhibit Greater Stem-Like Properties

29 September 2017

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Hypoxia-dependent inhibition of tumor cell susceptibility to CTL-mediated lysis involves NANOG induction in target cells

29 September 2017

1 reference

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Nanog-induced dedifferentiation of p53-deficient mouse astrocytes into brain cancer stem-like cells

29 September 2017

1 reference

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CD24 Liver Tumor-Initiating Cells Drive Self-Renewal and Tumor Initiation through STAT3-Mediated NANOG Regulation

29 September 2017

1 reference

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HIF induces human embryonic stem cell markers in cancer cells.

29 September 2017

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Stem cell marker (Nanog) and Stat-3 signaling promote MicroRNA-21 expression and chemoresistance in hyaluronan/CD44-activated head and neck squamous cell carcinoma cells

29 September 2017

1 reference

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LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells.

29 September 2017

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Expression of NANOG in human gliomas and its relationship with undifferentiated glioma cells

29 September 2017

1 reference

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NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation

29 September 2017

1 reference

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Malignant transformation of 293 cells induced by ectopic expression of human Nanog

29 September 2017

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Connecting transcriptional control to chromosome structure and human disease.

29 September 2017

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Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation.

29 September 2017

1 reference

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Expression of NANOG and NANOGP8 in a variety of undifferentiated and differentiated human cells

29 September 2017

1 reference

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NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53.

29 September 2017

1 reference

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Transcriptional properties of human NANOG1 and NANOG2 in acute leukemic cells.

29 September 2017

1 reference

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EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cells

29 September 2017

1 reference

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Over-expression of Nanog predicts tumor progression and poor prognosis in colorectal cancer

29 September 2017

1 reference

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Hyaluronan-CD44 interaction with protein kinase C(epsilon) promotes oncogenic signaling by the stem cell marker Nanog and the Production of microRNA-21, leading to down-regulation of the tumor suppressor protein PDCD4, anti-apoptosis, and chemothera

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509798

Functional evidence that the self-renewal gene NANOG regulates human tumor development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509798

Mouse fibroblasts lacking RB1 function form spheres and undergo reprogramming to a cancer stem cell phenotype

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509798

Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509798

Requirement of Nanog dimerization for stem cell self-renewal and pluripotency

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509798

Application of stem cell markers in search for neoplastic germ cells in dysgenetic gonads, extragonadal tumours, and in semen of infertile men.

29 September 2017

1 reference

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Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues

29 September 2017

1 reference

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Nanog induces hyperplasia without initiating tumors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4509798

Coexpression of stemness factors Oct4 and Nanog predict liver resection.

2 June 2018

1 reference

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NANOGP8 is a retrogene expressed in cancers

2 June 2018

1 reference

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SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity.

2 June 2018

1 reference

Differential expression of nanog1 and nanogp8 in colon cancer cells

21 January 2018

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A short G1 phase is an intrinsic determinant of naïve embryonic stem cell pluripotency.

21 January 2018

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A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A.

21 January 2018

1 reference

Oct4 and Nanog directly regulate Dnmt1 to maintain self-renewal and undifferentiated state in mesenchymal stem cells.

21 January 2018

1 reference

Dynamics of TET family expression in porcine preimplantation embryos is related to zygotic genome activation and required for the maintenance of NANOG.

21 January 2018

1 reference

A preclinical xenograft model identifies castration-tolerant cancer-repopulating cells in localized prostate tumors.

21 January 2018

1 reference

Nanog regulates self-renewal of cancer stem cells through the insulin-like growth factor pathway in human hepatocellular carcinoma

21 January 2018

1 reference

RNA interference-mediated silencing of NANOG leads to reduced proliferation and self-renewal, cell cycle arrest and apoptosis in T-cell acute lymphoblastic leukemia cells via the p53 signaling pathway

21 January 2018

1 reference

A study of embryonic stem cell-related proteins in human astrocytomas: identification of Nanog as a predictor of survival

21 January 2018

1 reference

Nanog: a potential biomarker for liver metastasis of colorectal cancer.

21 January 2018

1 reference

LGR5 and Nanog identify stem cell signature of pancreas beta cells which initiate pancreatic cancer

21 January 2018

1 reference

Stem cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-cadherin and FoxJ1 and contributes to adverse clinical outcome in ovarian cancers.

21 January 2018

1 reference

Nanog Is Highly Expressed in Ovarian Serous Cystadenocarcinoma and Correlated with Clinical Stage and Pathological Grade

21 January 2018

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12 December 2020

Sox2 expression in breast tumours and activation in breast cancer stem cells

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12 December 2020

Prognostic significance of NANOG and KLF4 for breast cancer

1 reference

12 December 2020

Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells

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12 December 2020

Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells

1 reference

12 December 2020

Identifiers

DOI

10.1002/STEM.2007

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821200 AND SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25821200 AND SRC:MED&resulttype=core&format=json

4 March 2020

PubMed publication ID

25821200

2 references