Lymph node fibroblastic reticular cells in health and disease (Q28087190)

title

Lymph node fibroblastic reticular cells in health and disease (English)

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25998961 AND SRC:MED&resulttype=core&format=json

12 June 2020

Sophie E Acton

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25998961 AND SRC:MED&resulttype=core&format=json

12 June 2020

Konstantin Knoblich

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25998961 AND SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Anne L. Fletcher

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Sophie E. Acton

2

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language of work or name

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June 2015

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Nature Reviews Immunology

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25998961 AND SRC:MED&resulttype=core&format=json

12 June 2020

volume

15

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25998961 AND SRC:MED&resulttype=core&format=json

12 June 2020

issue

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25998961 AND SRC:MED&resulttype=core&format=json

12 June 2020

page(s)

350-361

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25998961 AND SRC:MED&resulttype=core&format=json

Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes

12 June 2020

cites work

1 reference

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A chemokine-driven positive feedback loop organizes lymphoid follicles

20 March 2017

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Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2

20 March 2017

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An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells

20 March 2017

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Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation

20 March 2017

1 reference

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Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytes

20 March 2017

1 reference

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Overlapping roles of CXCL13, interleukin 7 receptor alpha, and CCR7 ligands in lymph node development

20 March 2017

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Rapid leukocyte migration by integrin-independent flowing and squeezing

20 March 2017

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Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes

7 April 2017

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Hippo/Yap signaling controls epithelial progenitor cell proliferation and differentiation in the embryonic and adult lung

7 April 2017

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Syk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells

29 September 2017

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The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Dendritic cells control fibroblastic reticular network tension and lymph node expansion

29 September 2017

1 reference

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Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implications

29 September 2017

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Antifibrotic therapy in simian immunodeficiency virus infection preserves CD4 T-cell populations and improves immune reconstitution with antiretroviral therapy

29 September 2017

1 reference

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B cell homeostasis and follicle confines are governed by fibroblastic reticular cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Lymph node fibroblastic reticular cell transplants show robust therapeutic efficacy in high-mortality murine sepsis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Fibroblastic reticular cells of the lymph node are required for retention of resting but not activated CD8 T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Fate mapping reveals origin and dynamics of lymph node follicular dendritic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Lymph node stromal cells acquire peptide-MHCII complexes from dendritic cells and induce antigen-specific CD4⁺ T cell tolerance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

CLEC-2 is required for development and maintenance of lymph nodes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Identification of a new stromal cell type involved in the regulation of inflamed B cell follicles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

The intestinal micro-environment imprints stromal cells to promote efficient Treg induction in gut-draining lymph nodes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Pathobiology of HIV/SIV-associated changes in secondary lymphoid tissues

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Poor immune reconstitution in HIV-infected patients associates with high percentage of regulatory CD4 T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Stromal and hematopoietic cells in secondary lymphoid organs: partners in immunity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Pathology of experimental aerosol Zaire ebolavirus infection in rhesus macaques.

29 September 2017

1 reference

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Mesenchymal cell differentiation during lymph node organogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Recombinant human interleukin-7 (CYT107) promotes T-cell recovery after allogeneic stem cell transplantation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

IL-7-producing stromal cells are critical for lymph node remodeling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Lymphotoxin-β receptor signaling through NF-κB2-RelB pathway reprograms adipocyte precursors as lymph node stromal cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Critical role of CD4 T cells in maintaining lymphoid tissue structure for immune cell homeostasis and reconstitution.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Reproducible isolation of lymph node stromal cells reveals site-dependent differences in fibroblastic reticular cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Immortalized clones of fibroblastic reticular cells activate virus-specific T cells during virus infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Fibroblastic reticular cells from lymph nodes attenuate T cell expansion by producing nitric oxide

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Regulation of T cell priming by lymphoid stroma.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Coordinated regulation of lymph node vascular-stromal growth first by CD11c cells and then by T and B cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

CLEC-2 signaling via Syk in myeloid cells can regulate inflammatory responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Immune reconstitution after a decade of combined antiretroviral therapies for human immunodeficiency virus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Lymph node stroma broaden the peripheral tolerance paradigm

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Fibroblastic reticular cell infection by hemorrhagic fever viruses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Lymph node-resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Ontogeny of stromal organizer cells during lymph node development.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Fibroblastic reticular cells and their role in viral hemorrhagic fevers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Collagen deposition limits immune reconstitution in the gut

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Deletional self-tolerance to a melanocyte/melanoma antigen derived from tyrosinase is mediated by a radio-resistant cell in peripheral and mesenteric lymph nodes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

A novel reticular stromal structure in lymph node cortex: an immuno-platform for interactions among dendritic cells, T cells and B cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Cooperating mechanisms of CXCR5 and CCR7 in development and organization of secondary lymphoid organs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Splenic T zone development is B cell dependent

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Loss of lymph node fibroblastic reticular cells and high endothelial cells is associated with humoral immunodeficiency in mouse graft-versus-host disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Lymph node stromal cells constrain immunity via MHC class II self-antigen presentation.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Marginal reticular cells: a stromal subset directly descended from the lymphoid tissue organizer.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Conduits mediate transport of low-molecular-weight antigen to lymph node follicles

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Fibroblast-type reticular stromal cells regulate the lymph node vasculature

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Direct presentation of antigen by lymph node stromal cells protects against CD8 T-cell-mediated intestinal autoimmunity.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5152733

Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells.

2 June 2018

1 reference

Follicular dendritic cells: dynamic antigen libraries.

21 January 2018

1 reference

Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex

21 January 2018

1 reference

Native adipose stromal cells egress from adipose tissue in vivo: evidence during lymph node activation.

21 January 2018

1 reference

Endothelial cell-specific lymphotoxin-β receptor signaling is critical for lymph node and high endothelial venule formation

21 January 2018

1 reference

Follicular dendritic cells emerge from ubiquitous perivascular precursors

21 January 2018

1 reference

Follicular dendritic cells help establish follicle identity and promote B cell retention in germinal centers

21 January 2018

1 reference

Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self

21 January 2018

1 reference

Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses

21 January 2018

1 reference

Presumptive lymph node organizers are differentially represented in developing mesenteric and peripheral nodes.

21 January 2018

1 reference

A stroma-derived defect in NF-kappaB2-/- mice causes impaired lymph node development and lymphocyte recruitment.

21 January 2018

1 reference

I kappa B kinase complex alpha kinase activity controls chemokine and high endothelial venule gene expression in lymph nodes and nasal-associated lymphoid tissue.

21 January 2018

1 reference

Different cytokines induce surface lymphotoxin-alphabeta on IL-7 receptor-alpha cells that differentially engender lymph nodes and Peyer's patches

21 January 2018

1 reference

Human mesenchymal stem cells isolated from bone marrow and lymphoid organs support tumor B-cell growth: role of stromal cells in follicular lymphoma pathogenesis

31 March 2020

1 reference

RANKL Induces Organized Lymph Node Growth by Stromal Cell Proliferation

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRI3846

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25998961 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 June 2020

1011371145

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25998961 AND SRC:MED&resulttype=core&format=json

12 June 2020

PubMed publication ID

25998961

2 references