Entropic clocks in the service of electrical signaling: 'Ball and chain' mechanisms for ion channel inactivation and clustering (Q28087125)

Limor Lewin

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Valerie Nirenberg

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Irit Orr

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Ofer Yifrach

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language of work or name

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14 September 2015

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589

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issue

19 Pt A

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page(s)

2441-7

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Genetic analysis of protein stability and function

cites work

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

De novo enzymes by computational design

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Computational protein design of ligand binding and catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Computational tools for designing and engineering enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Biophysical and molecular mechanisms of Shaker potassium channel inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Inactivation of voltage-gated cardiac K channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

The inactivation gate of the Shaker K channel behaves like an open-channel blocker.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Interactions of amino terminal domains of Shaker K channels with a pore blocking site studied with synthetic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Editing of human KV1.1 channel mRNAs disrupts binding of the N-terminus tip at the intracellular cavity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

A random flight chain model for the tether of the Shaker K channel inactivation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Inactivation of the sodium channel. II. Gating current experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Regulation of fast inactivation of cloned mammalian IK(A) channels by cysteine oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Trypsin-sensitive, rapid inactivation of a calcium-activated potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Intrinsically disordered protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Intrinsic disorder and protein function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Intrinsic disorder in the C-terminal domain of the Shaker voltage-activated K channel modulates its interaction with scaffold proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Alternative splicing modulates Kv channel clustering through a molecular ball and chain mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Clustering of Shaker-type K channels by interaction with a family of membrane-associated guanylate kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

DLG differentially localizes Shaker K -channels in the central nervous system and retina of Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

PSD-95 and SAP97 exhibit distinct mechanisms for regulating K( ) channel surface expression and clustering

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Lipid- and protein-mediated multimerization of PSD-95: implications for receptor clustering and assembly of synaptic protein networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Disulfide-linked head-to-head multimerization in the mechanism of ion channel clustering by PSD-95.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Clustering membrane proteins: It's all coming together with the PSD-95/SAP90 protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Ion conduction pore is conserved among potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Voltage sensor of Kv1.2: structural basis of electromechanical coupling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Action-potential propagation gated by an axonal IA-like K conductance in hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Regulation of back-propagating action potentials in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Subcellular localization of K channels in mammalian brain neurons: remarkable precision in the midst of extraordinary complexity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Channel density regulation of firing patterns in a cortical neuron model

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Ion channel density regulates switches between regular and fast spiking in soma but not in axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Density of voltage-gated potassium channels is a bifurcation parameter in pyramidal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Statistical properties predicted by the ball and chain model of channel inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

NMR structure of inactivation gates from mammalian voltage-dependent potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Control of K channel gating by protein phosphorylation: structural switches of the inactivation gate

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Controlling entropy to tune the functions of intrinsically disordered regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Side-chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Multiple potassium-channel components are produced by alternative splicing at the Shaker locus in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Tissue-specific alternative splicing of hybrid Shaker/lacZ genes correlates with kinetic differences in Shaker K currents in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Four cDNA clones from the Shaker locus of Drosophila induce kinetically distinct A-type potassium currents in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

A-type potassium channels expressed from Shaker locus cDNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Alternative splicing in concert with protein intrinsic disorder enables increased functional diversity in multicellular organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Alternative splicing of intrinsically disordered regions and rewiring of protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Thermodynamic analysis of biomolecular interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Speeding molecular recognition by using the folding funnel: the fly-casting mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Capillarity theory for the fly-casting mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

N-Terminal Palmitoylation of PSD-95 Regulates Association with Cell Membranes and Interaction with K Channel Kv1.4

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Inactivation properties of voltage-gated K channels altered by presence of beta-subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Energetics of Shaker K channels block by inactivation peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Multiple intermediate states precede pore block during N-type inactivation of a voltage-gated potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Oxidation of NADPH on Kvβ1 inhibits ball-and-chain type inactivation by restraining the chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

A conserved pre-block interaction motif regulates potassium channel activation and N-type inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Molecular determinants of intracellular pH modulation of human Kv1.4 N-type inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Heme impairs the ball-and-chain inactivation of potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Intrinsically unstructured proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Linking folding and binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

The rules of disorder or why disorder rules

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Classification of intrinsically disordered regions and proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Intrinsically disordered C-terminal segments of voltage-activated potassium channels: a possible fishing rod-like mechanism for channel binding to scaffold proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

Fifty years of inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016/J.FEBSLET.2015.06.010

10.1016/J.FEBSLET.2015.06.010

21 January 2018

Identifiers

DOI

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PubMed publication ID

26112606

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