Conformational analysis of misfolded protein aggregation by FRET and live-cell imaging techniques (Q28083085)

Förster resonance energy transfer

main subject

1 reference

19 September 2019

1 reference

inferred from abstract

protein

1 reference

PubMed publication ID

1

Akira Kitamura

1 reference

3

Masataka Kinjo

1 reference

2

Kazuhiro Nagata

1 reference

International Journal of Molecular Sciences

language of work or name

1 reference

16 March 2015

4 references

19 September 2019

8 October 2023

28 October 2023

4 references

19 September 2019

8 October 2023

28 October 2023

16

1 reference

issue

3

1 reference

page(s)

6076-92

1 reference

Creative Commons Attribution

copyright license

3 references

19 September 2019

8 October 2023

28 October 2023

0 references

Spreading of pathology in neurodegenerative diseases: a focus on human studies

1 reference

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The 1.6 Å resolution structure of a FRET-optimized Cerulean fluorescent protein

20 March 2017

1 reference

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Ligand binding and aggregation of pathogenic SOD1

20 March 2017

1 reference

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HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?

20 March 2017

1 reference

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Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%.

20 March 2017

1 reference

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Protein Folding and Quality Control in the ER

20 March 2017

1 reference

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Prions, protein homeostasis, and phenotypic diversity

20 March 2017

1 reference

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Misfolded proteins partition between two distinct quality control compartments

20 March 2017

1 reference

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20 March 2017

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HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

20 March 2017

1 reference

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RNA sequence- and shape-dependent recognition by proteins in the ribonucleoprotein particle

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

20 March 2017

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20 March 2017

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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

29 September 2017

1 reference

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Protein misfolding, functional amyloid, and human disease

20 March 2017

2 references

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20 March 2017

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Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

7 April 2017

1 reference

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Adapting proteostasis for disease intervention

20 March 2017

1 reference

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Proteasomes activate aggresome disassembly and clearance by producing unanchored ubiquitin chains

20 March 2017

1 reference

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Protein aggregation and neurodegenerative disease

20 March 2017

2 references

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20 March 2017

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Molecular chaperones in protein folding and proteostasis

7 April 2017

1 reference

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Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

7 April 2017

1 reference

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Aggresomes, inclusion bodies and protein aggregation

7 April 2017

1 reference

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Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum

7 April 2017

1 reference

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Failure of ubiquitin proteasome system: risk for neurodegenerative diseases

29 September 2017

1 reference

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Lost after translation: missorting of Tau protein and consequences for Alzheimer disease

29 September 2017

1 reference

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Control of systemic proteostasis by the nervous system.

29 September 2017

1 reference

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Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

29 September 2017

1 reference

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Organismal proteostasis: role of cell-nonautonomous regulation and transcellular chaperone signaling

29 September 2017

1 reference

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Quantitative in vivo fluorescence cross-correlation analyses highlight the importance of competitive effects in the regulation of protein-protein interactions

29 September 2017

1 reference

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How the nucleus copes with proteotoxic stress

29 September 2017

1 reference

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Proteostasis in endoplasmic reticulum--new mechanisms in kidney disease

29 September 2017

1 reference

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Dimerization, oligomerization, and aggregation of human amyotrophic lateral sclerosis copper/zinc superoxide dismutase 1 protein mutant forms in live cells

29 September 2017

1 reference

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Dysregulation of the proteasome increases the toxicity of ALS-linked mutant SOD1.

29 September 2017

1 reference

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Long-distance integration of nuclear ERK signaling triggered by activation of a few dendritic spines

29 September 2017

1 reference

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Spatial sequestration of misfolded proteins by a dynamic chaperone pathway enhances cellular fitness during stress

29 September 2017

1 reference

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Determination of dissociation constant of the NFκB p50/p65 heterodimer using fluorescence cross-correlation spectroscopy in the living cell

29 September 2017

1 reference

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Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation formation

29 September 2017

1 reference

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Minimum set of mutations needed to optimize cyan fluorescent proteins for live cell imaging.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Red fluorescent proteins: chromophore formation and cellular applications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Compartmentalization of superoxide dismutase 1 (SOD1G93A) aggregates determines their toxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

An orange fluorescent protein with a large Stokes shift for single-excitation multicolor FCCS and FRET imaging

29 September 2017

1 reference

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Quality Control of Mitochondrial Proteostasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Amyloid structure: conformational diversity and consequences

29 September 2017

1 reference

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Nucleolar aggresomes as counterparts of cytoplasmic aggresomes in proteotoxic stress. Proteasome inhibitors induce nuclear ribonucleoprotein inclusions that accumulate several key factors of neurodegenerative diseases and cancer

29 September 2017

1 reference

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Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast

29 September 2017

1 reference

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A novel fluorescent sensor protein for visualization of redox states in the cytoplasm and in peroxisomes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Amyloid oligomers: dynamics and toxicity in the cytosol and nucleus

29 September 2017

1 reference

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Quantitative study of synthetic Hox transcription factor-DNA interactions in live cells

29 September 2017

1 reference

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Fluorescent protein-based redox probes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Quantitative comparison of different fluorescent protein couples for fast FRET-FLIM acquisition.

29 September 2017

1 reference

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Highly sensitive and quantitative FRET-FLIM imaging in single dendritic spines using improved non-radiative YFP

29 September 2017

1 reference

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Mutant SOD1 detoxification mechanisms in intact single cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Soluble polyglutamine oligomers formed prior to inclusion body formation are cytotoxic

29 September 2017

1 reference

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Fluorescence as a method to reveal structures and membrane-interactions of amyloidogenic proteins

29 September 2017

1 reference

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The chaperonin TRiC controls polyglutamine aggregation and toxicity through subunit-specific interactions

29 September 2017

1 reference

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29 September 2017

1 reference

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Sensitivity of CFP/YFP and GFP/mCherry pairs to donor photobleaching on FRET determination by fluorescence lifetime imaging microscopy in living cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Fluorescence cross-correlation spectroscopy in living cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Structural properties and neuronal toxicity of amyotrophic lateral sclerosis-associated Cu/Zn superoxide dismutase 1 aggregates.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Expanded dynamic range of fluorescent indicators for Ca(2 ) by circularly permuted yellow fluorescent proteins.

29 September 2017

1 reference

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Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

The ubiquitin proteasome system in neurodegenerative diseases: sometimes the chicken, sometimes the egg.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Visualization of the spatial and temporal dynamics of intracellular signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Studying protein dynamics in living cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Rapid caspase-3 activation during apoptosis revealed using fluorescence-resonance energy transfer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Protein aggregation and pathogenesis of Huntington's disease: mechanisms and correlations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Monitoring protein conformations and interactions by fluorescence resonance energy transfer between mutants of green fluorescent protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Architecture of polyglutamine-containing fibrils from time-resolved fluorescence decay

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Intact protein folding in the glutathione-depleted endoplasmic reticulum implicates alternative protein thiol reductants

2 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

2 June 2018

https://pubmed.ncbi.nlm.nih.gov/25785563

12 December 2020

inferred from PubMed ID database lookup

Peroxisomal proteostasis involves a Lon family protein that functions as protease and chaperone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Genetically encoded probes for measurement of intracellular calcium

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Endoplasmic reticulum Ca2 increases enhance mutant glucocerebrosidase proteostasis.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Oxygen-induced maturation of SOD1: a key role for disulfide formation by the copper chaperone CCS.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4394520

Chaperonin TRiC promotes the assembly of polyQ expansion proteins into nontoxic oligomers

2 June 2018

1 reference

https://api.crossref.org/works/10.3390/IJMS16036076

Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/IJMS16036076

Detection of polyglutamine protein oligomers in cells by fluorescence correlation spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/IJMS16036076

Huntingtin and mutant SOD1 form aggregate structures with distinct molecular properties in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/IJMS16036076

Binding modes of thioflavin-T to the single-layer beta-sheet of the peptide self-assembly mimics

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/IJMS16036076

Amyotrophic lateral sclerosis mutations have the greatest destabilizing effect on the apo- and reduced form of SOD1, leading to unfolding and oxidative aggregation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/IJMS16036076

An intersubunit disulfide bond prevents in vitro aggregation of a superoxide dismutase-1 mutant linked to familial amytrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/IJMS16036076

Complementary methods for studies of protein interactions in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/IJMS16036076

Single-cell fluorescence resonance energy transfer analysis demonstrates that caspase activation during apoptosis is a rapid process. Role of caspase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/IJMS16036076

Spatio-temporal activation of caspase revealed by indicator that is insensitive to environmental effects

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/IJMS16036076

A high-throughput method for development of FRET-based indicators for proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/IJMS16036076

Direct detection of caspase-3 activation in single live cells by cross-correlation analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/IJMS16036076

The interaction of Hsp104 with yeast prion Sup35 as analyzed by fluorescence cross-correlation spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/IJMS16036076

An ultramarine fluorescent protein with increased photostability and pH insensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/IJMS16036076

Redox sensor proteins for highly sensitive direct imaging of intracellular redox state

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/IJMS16036076

Firefly luciferase mutants as sensors of proteome stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3390/IJMS16036076

Application of the fluorescence resonance energy transfer method for studying the dynamics of caspase-3 activation during UV-induced apoptosis in living HeLa cells

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/25785563

12 December 2020

inferred from PubMed ID database lookup

Polyglutamine protein aggregates are dynamic

1 reference

https://pubmed.ncbi.nlm.nih.gov/25785563

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.3390/IJMS16036076

0 references

Fatcat ID

release_bqt5u4a2vvdpfe3j2v4oo67xwy

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bqt5u4a2vvdpfe3j2v4oo67xwy

24 November 2022

mapped directly with Wikidata item

1 reference

PubMed publication ID

25785563

1 reference