TGF-β signaling and its targeting for glioma treatment (Q28082042)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26045979 AND SRC:MED&resulttype=core&format=json

16 February 2020

review article

1 reference

title

TGF-β signaling and its targeting for glioma treatment (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26045979 AND SRC:MED&resulttype=core&format=json

16 February 2020

author name string

Jianfeng Han

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26045979 AND SRC:MED&resulttype=core&format=json

16 February 2020

Christopher A Alvarez-Breckenridge

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26045979 AND SRC:MED&resulttype=core&format=json

16 February 2020

Qi-En Wang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26045979 AND SRC:MED&resulttype=core&format=json

16 February 2020

Jianhua Yu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26045979 AND SRC:MED&resulttype=core&format=json

16 February 2020

language of work or name

1 reference

15 February 2015

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26045979 AND SRC:MED&resulttype=core&format=json

American Journal of Cancer Research

16 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26045979 AND SRC:MED&resulttype=core&format=json

16 February 2020

volume

5

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26045979 AND SRC:MED&resulttype=core&format=json

16 February 2020

issue

3

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26045979 AND SRC:MED&resulttype=core&format=json

16 February 2020

page(s)

945-955

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26045979 AND SRC:MED&resulttype=core&format=json

The 2007 WHO classification of tumours of the central nervous system

16 February 2020

cites work

1 reference

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Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

20 March 2017

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TGF-β Receptor Inhibitors Target the CD44high/Id1high Glioma-Initiating Cell Population in Human Glioblastoma

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7 April 2017

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Pharmacokinetic, pharmacodynamic and biomarker evaluation of transforming growth factor-β receptor I kinase inhibitor, galunisertib, in phase 1 study in patients with advanced cancer

7 April 2017

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First-in-human dose study of the novel transforming growth factor-β receptor I kinase inhibitor LY2157299 monohydrate in patients with advanced cancer and glioma

29 September 2017

1 reference

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Natural killer cells eradicate galectin-1-deficient glioma in the absence of adaptive immunity

29 September 2017

1 reference

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Focal radiation therapy combined with 4-1BB activation and CTLA-4 blockade yields long-term survival and a protective antigen-specific memory response in a murine glioma model

29 September 2017

1 reference

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Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors.

29 September 2017

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Intratumoral IL-12 combined with CTLA-4 blockade elicits T cell-mediated glioma rejection

29 September 2017

1 reference

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CBTRUS statistical report: Primary brain and central nervous system tumors diagnosed in the United States in 2006-2010.

29 September 2017

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TGF-β-induced miR10a/b expression promotes human glioma cell migration by targeting PTEN.

29 September 2017

1 reference

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Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth.

29 September 2017

1 reference

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TGF-β1 enhances tumor-induced angiogenesis via JNK pathway and macrophage infiltration in an improved zebrafish embryo/xenograft glioma model

29 September 2017

1 reference

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TGF-β induces miR-182 to sustain NF-κB activation in glioma subsets.

29 September 2017

1 reference

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Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization.

29 September 2017

1 reference

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Retracted: Concomitant Targeting of EGF Receptor, TGF-beta and Src Points to a Novel Therapeutic Approach in Pancreatic Cancer

29 September 2017

1 reference

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Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β.

29 September 2017

1 reference

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Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-β1 signaling pathway

29 September 2017

1 reference

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Understanding the role of cytokines in Glioblastoma Multiforme pathogenesis

29 September 2017

1 reference

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Smad phosphoisoform signaling specificity: the right place at the right time

29 September 2017

1 reference

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Increased migration of a human glioma cell line after in vitro CyberKnife irradiation.

29 September 2017

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Exploring anti-TGF-β therapies in cancer and fibrosis

29 September 2017

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Trimodal Glioblastoma Treatment Consisting of Concurrent Radiotherapy, Temozolomide, and the Novel TGF-β Receptor I Kinase Inhibitor LY2109761

29 September 2017

1 reference

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Tumor localization of an anti-TGF-β antibody and its effects on gliomas

29 September 2017

1 reference

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Targeted therapy for high-grade glioma with the TGF-β2 inhibitor trabedersen: results of a randomized and controlled phase IIb study

29 September 2017

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Glioma cancer stem cells induce immunosuppressive macrophages/microglia

29 September 2017

1 reference

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Targeting the transforming growth factor-beta signaling pathway in human cancer

29 September 2017

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Treatment of malignant gliomas with TGF-beta2 antisense oligonucleotides

29 September 2017

1 reference

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Systemic inhibition of transforming growth factor-beta in glioma-bearing mice improves the therapeutic efficacy of glioma-associated antigen peptide vaccines

29 September 2017

1 reference

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Cancer stem cells: controversial or just misunderstood?

29 September 2017

1 reference

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NK cells recognize and kill human glioblastoma cells with stem cell-like properties

29 September 2017

1 reference

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Glioma gene therapy with soluble transforming growth factor-beta receptors II and III.

29 September 2017

1 reference

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TGF-beta utilizes SMAD3 to inhibit CD16-mediated IFN-gamma production and antibody-dependent cellular cytotoxicity in human NK cells

29 September 2017

1 reference

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Glioblastoma-secreted factors induce IGFBP7 and angiogenesis by modulating Smad-2-dependent TGF-beta signaling

29 September 2017

1 reference

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LY2109761, a novel transforming growth factor beta receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis

29 September 2017

1 reference

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Blocking transforming growth factor-beta up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells

29 September 2017

1 reference

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Endoglin in angiogenesis and vascular diseases

29 September 2017

1 reference

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Molecular pathology of malignant gliomas

29 September 2017

1 reference

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Inhibition of TGF-beta2 with AP 12009 in recurrent malignant gliomas: from preclinical to phase I/II studies

29 September 2017

1 reference

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TGF-beta and metalloproteinases differentially suppress NKG2D ligand surface expression on malignant glioma cells

29 September 2017

1 reference

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TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance

29 September 2017

1 reference

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Radiation enhances the invasive potential of primary glioblastoma cells via activation of the Rho signaling pathway

29 September 2017

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Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo

29 September 2017

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SD-208, a novel transforming growth factor beta receptor I kinase inhibitor, inhibits growth and invasiveness and enhances immunogenicity of murine and human glioma cells in vitro and in vivo

29 September 2017

1 reference

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RNA interference targeting transforming growth factor-beta enhances NKG2D-mediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo.

29 September 2017

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29 September 2017

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SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility.

29 September 2017

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The two faces of transforming growth factor beta in carcinogenesis

29 September 2017

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Transforming growth factor-beta signaling through the Smad pathway: role in extracellular matrix gene expression and regulation

29 September 2017

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Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta.

29 September 2017

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Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression

29 September 2017

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Malignant glioma biology: role for TGF-beta in growth, motility, angiogenesis, and immune escape

29 September 2017

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Role of TGF-beta in immune-evasion of cancer

29 September 2017

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Determinants of specificity in TGF-beta signal transduction.

29 September 2017

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TGF-beta downregulates the activating receptor NKG2D on NK cells and CD8 T cells in glioma patients

29 September 2017

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Infiltrating CTLs in human glioblastoma establish immunological synapses with tumorigenic cells

2 June 2018

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Transforming growth factor-beta: vasculogenesis, angiogenesis, and vessel wall integrity

2 June 2018

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2 June 2018

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Effect of the expression of transforming growth factor-beta 2 in primary human glioblastomas on immunosuppression and loss of immune surveillance

2 June 2018

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Transforming growth factor-beta 2 down-regulates HLA-DR antigen expression on human malignant glioma cells.

2 June 2018

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IL-10 and TGF-β2 are overexpressed in tumor spheres cultured from human gliomas.

28 July 2018

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Autocrine TGF-beta signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors.

27 November 2018

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TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma

27 November 2018

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Microglia-derived TGF-beta as an important regulator of glioblastoma invasion--an inhibition of TGF-beta-dependent effects by shRNA against human TGF-beta type II receptor.

27 November 2018

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High TGFbeta-Smad activity confers poor prognosis in glioma patients and promotes cell proliferation depending on the methylation of the PDGF-B gene

27 November 2018

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Pro- and antiinflammatory cytokine signaling: reciprocal antagonism regulates interferon-gamma production by human natural killer cells.

27 November 2018

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27 November 2018

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Enhanced expression of transforming growth factor‐β and its type‐I and type‐II receptors in human glioblastoma

27 November 2018

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Transforming growth factor beta and cell cycle regulation

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/26045979

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Excessive production of transforming growth-factor beta 1 can play an important role in the development of tumorigenesis by its action for angiogenesis: validity of neutralizing antibodies to block tumor growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/26045979

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

TGF-beta enhances macrophage ability to produce IL-10 in normal and tumor-bearing mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/26045979

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

1192708

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

1192708

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26045979 AND SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

26045979

2 references

Consolidated OpenCitations Corpus – April 2017

1192708