ERK5 and Cell Proliferation: Nuclear Localization Is What Matters (Q28078572)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713878 AND SRC:MED&resulttype=core&format=json

25 March 2020

review article

1 reference

title

ERK5 and Cell Proliferation: Nuclear Localization Is What Matters (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713878 AND SRC:MED&resulttype=core&format=json

25 March 2020

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713878 AND SRC:MED&resulttype=core&format=json

25 March 2020

author name string

Nestor Gomez

series ordinal

1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713878 AND SRC:MED&resulttype=core&format=json

25 March 2020

Tatiana Erazo

series ordinal

2

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713878 AND SRC:MED&resulttype=core&format=json

25 March 2020

language of work or name

1 reference

22 September 2016

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713878 AND SRC:MED&resulttype=core&format=json

Frontiers in Cell and Developmental Biology

25 March 2020

published in

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713878 AND SRC:MED&resulttype=core&format=json

25 March 2020

volume

4

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713878 AND SRC:MED&resulttype=core&format=json

25 March 2020

page(s)

105

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713878 AND SRC:MED&resulttype=core&format=json

Dual kinase-bromodomain inhibitors for rationally designed polypharmacology

25 March 2020

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Canonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complex

20 March 2017

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The kinase ALK stimulates the kinase ERK5 to promote the expression of the oncogene MYCN in neuroblastoma

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Therapeutic potential of ERK5 targeting in triple negative breast cancer

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XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism.

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Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer

29 September 2017

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ERK5/BMK1 is a novel target of the tumor suppressor VHL: implication in clear cell renal carcinoma.

29 September 2017

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Extracellular signal-regulated kinase 5: a potential therapeutic target for malignant mesotheliomas

29 September 2017

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Mir143 expression inversely correlates with nuclear ERK5 immunoreactivity in clinical prostate cancer

29 September 2017

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The extracellular-regulated protein kinase 5 (ERK5) promotes cell proliferation through the down-regulation of inhibitors of cyclin dependent protein kinases (CDKs).

29 September 2017

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ERK5: structure, regulation and function.

29 September 2017

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ERK5 and its role in tumour development

29 September 2017

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ERK5 regulates invasiveness of osteosarcoma by inducing MMP-9.

29 September 2017

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ERK5 signalling in prostate cancer promotes an invasive phenotype

29 September 2017

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29 September 2017

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Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor.

29 September 2017

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Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling

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ERK5 knockdown generates mouse leukemia cells with low MHC class I levels that activate NK cells and block tumorigenesis.

29 September 2017

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29 September 2017

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29 September 2017

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ERK5 activates NF-kappaB in leukemic T cells and is essential for their growth in vivo.

29 September 2017

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29 September 2017

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The unique C-terminal tail of the mitogen-activated protein kinase ERK5 regulates its activation and nuclear shuttling.

29 September 2017

1 reference

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Granulocyte colony-stimulating factor induces ERK5 activation, which is differentially regulated by protein-tyrosine kinases and protein kinase C. Regulation of cell proliferation and survival

29 September 2017

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ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain

29 September 2017

1 reference

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Role of BMK1 in regulation of growth factor-induced cellular responses

29 September 2017

1 reference

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Activation of the protein kinase ERK5/BMK1 by receptor tyrosine kinases. Identification and characterization of a signaling pathway to the nucleus

29 September 2017

1 reference

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ERK1/2 MAP kinases promote cell cycle entry by rapid, kinase-independent disruption of retinoblastoma-lamin A complexes.

29 September 2017

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Activation of a C-terminal transcriptional activation domain of ERK5 by autophosphorylation.

2 June 2018

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2 June 2018

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Regulation of c-Fos and Fra-1 by the MEK5-ERK5 pathway

2 June 2018

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Changes in apoptosis-related pathways in acute myelocytic leukemia

2 June 2018

1 reference

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ERK5 is a critical mediator of inflammation-driven cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FCELL.2016.00105

Erk5 is activated and acts as a survival factor in mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FCELL.2016.00105

Alternative ERK5 regulation by phosphorylation during the cell cycle.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FCELL.2016.00105

MEKK2 regulates the coordinate activation of ERK5 and JNK in response to FGF-2 in fibroblasts

21 January 2018

1 reference

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Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FCELL.2016.00105

Activation of cyclin D1 expression by the ERK5 cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FCELL.2016.00105

The MAP kinase ERK5 binds to and phosphorylates p90 RSK.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FCELL.2016.00105

The mitogen-activated protein kinase ERK5 regulates the development and growth of hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FCELL.2016.00105

Induction of human Cdc37 in prostate cancer correlates with the ability of targeted Cdc37 expression to promote prostatic hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FCELL.2016.00105

ERK5 differentially regulates PDGF-induced proliferation and migration of hepatic stellate cells

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/27713878

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cyclin D1 overexpression is not a specific grouping marker, but may collaborate with CDC37 in myeloma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27713878

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Aberrant expression of extracellular signal-regulated kinase 5 in human prostate cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/27713878

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FCELL.2016.00105

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713878 AND SRC:MED&resulttype=core&format=json

25 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27713878 AND SRC:MED&resulttype=core&format=json

25 March 2020

PubMed publication ID

27713878

2 references