Hedgehog pathway inhibition in advanced basal cell carcinoma: latest evidence and clinical usefulness (Q28072902)

L. Chen

series ordinal

2

1 reference

M. R. Migden

series ordinal

3

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language of work or name

1 reference

September 2016

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Therapeutic advances in medical oncology

published in

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volume

8

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issue

5

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page(s)

375-82

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An Investigator-Initiated Open-Label Trial of Sonidegib in Advanced Basal Cell Carcinoma Patients Resistant to Vismodegib

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Smoothened variants explain the majority of drug resistance in basal cell carcinoma

20 March 2017

1 reference

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New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada

20 March 2017

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Activating Smoothened mutations in sporadic basal-cell carcinoma

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

20 March 2017

1 reference

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New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)

20 March 2017

1 reference

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Surgical excision versus Mohs' micrographic surgery for primary and recurrent basal-cell carcinoma of the face: a prospective randomised controlled trial with 5-years' follow-up

20 March 2017

1 reference

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Identification of mutations in the human PATCHED gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas

20 March 2017

1 reference

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Human homolog of patched, a candidate gene for the basal cell nevus syndrome

20 March 2017

1 reference

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Mutations affecting segment number and polarity in Drosophila

20 March 2017

1 reference

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Treatment with two different doses of sonidegib in patients with locally advanced or metastatic basal cell carcinoma (BOLT): a multicentre, randomised, double-blind phase 2 trial.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Pivotal ERIVANCE basal cell carcinoma (BCC) study: 12-month update of efficacy and safety of vismodegib in advanced BCC.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Hedgehog pathway blockade with the cancer drug LDE225 disrupts taste organs and taste sensation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Vismodegib, an antagonist of hedgehog signaling, directly alters taste molecular signaling in taste buds

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Vismodegib for the treatment of basal cell carcinoma: results and implications of the ERIVANCE BCC trial

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Efficacy and safety of vismodegib in advanced basal-cell carcinoma.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Phase I trial of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Non-melanoma skin cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Inhibition of the hedgehog pathway in advanced basal-cell carcinoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Basal cell carcinomas: attack of the hedgehog

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

In vivo inhibition of endogenous brain tumors through systemic interference of Hedgehog signaling in mice.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

The teratogenic Veratrum alkaloid cyclopamine inhibits sonic hedgehog signal transduction.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Dysgeusia and weight loss under treatment with vismodegib: benefit of nutritional management

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Effect of Calcium Channel Blockade on Vismodegib-Induced Muscle Cramps

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Absorption, distribution, metabolism, and excretion (ADME) of ¹⁴C-sonidegib (LDE225) in healthy volunteers

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

A phase I, multicenter, open-label, first-in-human, dose-escalation study of the oral smoothened inhibitor Sonidegib (LDE225) in patients with advanced solid tumors

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Pharmacokinetic Dose-Scheduling Study of Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Patients with Locally Advanced or Metastatic Solid Tumors

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Topical treatment of Basal cell carcinomas in nevoid Basal cell carcinoma syndrome with a smoothened inhibitor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4981290

Persistent alopecia induced by vismodegib

2 June 2018

1 reference

https://api.crossref.org/works/10.1177/1758834016653605

Teratogen-mediated inhibition of target tissue response to Shh signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1758834016653605

Advanced Basal Cell Carcinoma: Epidemiology and Therapeutic Innovations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1758834016653605

Genomic analysis of smoothened inhibitor resistance in basal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177/1758834016653605

Essential role for Sonic hedgehog during hair follicle morphogenesis

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/27583029

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Design and synthesis of inhibitors of Hedgehog signaling based on the alkaloid cyclopamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/27583029

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Influence of calcium channel blocker drugs in neuromuscular transmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/27583029

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1177/1758834016653605

1 reference

1 reference

PubMed publication ID

27583029

1 reference