The Role of Connexins in Wound Healing and Repair: Novel Therapeutic Approaches (Q28068283)

Teresa Tan

2

1 reference

Catherine Chan

3

1 reference

Victoria Laxton

4

1 reference

Yin Wah Fiona Chan

5

1 reference

Tong Liu

6

1 reference

Wing Tak Wong

7

1 reference

language of work or name

1 reference

6 December 2016

1 reference

published in

Frontiers in Physiology

1 reference

volume

7

1 reference

page(s)

596

1 reference

Mechanisms of Electrical Activation and Conduction in the Gastrointestinal System: Lessons from Cardiac Electrophysiology

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Topical administration of a connexin43-based peptide augments healing of chronic neuropathic diabetic foot ulcers: A multicenter, randomized trial

29 September 2017

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Sodium channels in the Cx43 gap junction perinexus may constitute a cardiac ephapse: an experimental and modeling study

29 September 2017

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The effect of a connexin43-based Peptide on the healing of chronic venous leg ulcers: a multicenter, randomized trial

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Connexin expression patterns in diseased human corneas

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Specific Cx43 phosphorylation events regulate gap junction turnover in vivo

29 September 2017

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29 September 2017

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Catecholamine stress alters neutrophil trafficking and impairs wound healing by β2-adrenergic receptor-mediated upregulation of IL-6.

29 September 2017

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The use of connexin-based therapeutic approaches to target inflammatory diseases.

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A synthetic connexin 43 mimetic peptide augments corneal wound healing

29 September 2017

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Connexin 43 is involved in the generation of human-induced pluripotent stem cells

29 September 2017

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A comparison of epithelial-to-mesenchymal transition and re-epithelialization

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Sertoli-cell-specific knockout of connexin 43 leads to multiple alterations in testicular gene expression in prepubertal mice

29 September 2017

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29 September 2017

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29 September 2017

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Slug Is Upregulated during Wound Healing and Regulates Cellular Phenotypes in Corneal Epithelial Cells

29 September 2017

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Connexins in wound healing; perspectives in diabetic patients.

29 September 2017

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29 September 2017

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Endothelial mesenchymal transformation mediated by IL-1β-induced FGF-2 in corneal endothelial cells

29 September 2017

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Connexin43 phosphorylation in brain, cardiac, endothelial and epithelial tissues

29 September 2017

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29 September 2017

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Human dermal fibroblasts derived from oculodentodigital dysplasia patients suggest that patients may have wound-healing defects

29 September 2017

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29 September 2017

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29 September 2017

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Connexin 43 mimetic peptide Gap27 reveals potential differences in the role of Cx43 in wound repair between diabetic and non-diabetic cells

29 September 2017

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29 September 2017

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Targeting connexin 43 in diabetic wound healing: future perspectives

29 September 2017

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29 September 2017

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29 September 2017

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A gene signature of nonhealing venous ulcers: potential diagnostic markers

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Downregulation of connexin40 is associated with coronary endothelial cell dysfunction in streptozotocin-induced diabetic mice

29 September 2017

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29 September 2017

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29 September 2017

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Protein kinase C spatially and temporally regulates gap junctional communication during human wound repair via phosphorylation of connexin43 on serine368.

29 September 2017

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TGF-beta signal transduction in corneal wound healing as a therapeutic target

29 September 2017

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Characterization of putative stem cell phenotype in human limbal epithelia

29 September 2017

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29 September 2017

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Selective permeability of gap junction channels

29 September 2017

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Gap junction channel gating

29 September 2017

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Gap junction synthesis and degradation as therapeutic targets

29 September 2017

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Formation of the gap junction nexus: binding partners for connexins

29 September 2017

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Emerging issues of connexin channels: biophysics fills the gap.

29 September 2017

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Regeneration of rabbit cornea following excimer laser photorefractive keratectomy: a study on gap junctions, epithelial junctions and epidermal growth factor receptor expression in correlation with cell proliferation

29 September 2017

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v-Src phosphorylation of connexin 43 on Tyr247 and Tyr265 disrupts gap junctional communication

29 September 2017

1 reference

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Connexin mimetic peptides: specific inhibitors of gap-junctional intercellular communication

29 September 2017

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Corneal epithelial wound healing

29 September 2017

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Phosphorylation of connexin43 on serine368 by protein kinase C regulates gap junctional communication

29 September 2017

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29 September 2017

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Wounding alters epidermal connexin expression and gap junction-mediated intercellular communication

29 September 2017

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29 September 2017

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Switch in gap junction protein expression is associated with selective changes in junctional permeability during keratinocyte differentiation

29 September 2017

1 reference

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Increased gap junction assembly between cultured cells upon cholesterol supplementation

29 September 2017

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Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques

29 September 2017

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29 September 2017

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Transmission of hormonal stimulation by cell-to-cell communication

29 September 2017

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29 September 2017

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Both transmural dispersion of repolarization and of refractoriness are poor predictors of arrhythmogenicity: a role for iCEB (QT/QRS)?

29 September 2017

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The action of mimetic peptides on connexins protects fibroblasts from the negative effects of ischemia reperfusion

2 June 2018

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Protective effects of carbenoxolone are associated with attenuation of oxidative stress in ischemic brain injury

2 June 2018

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Effect of gap junction on the cardioprotection of ischemic postconditioning in rat heart

2 June 2018

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Overexpression of connexin26 in the basal keratinocytes reduces sensitivity to tumor promoter TPA.

2 June 2018

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Hypoxia in high glucose followed by reoxygenation in normal glucose reduces the viability of cortical astrocytes through increased permeability of connexin 43 hemichannels

2 June 2018

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ATP release by cardiac myocytes in a simulated ischaemia model: inhibition by a connexin mimetic and enhancement by an antiarrhythmic peptide

2 June 2018

1 reference

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2 June 2018

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Upregulation of connexin 26 is a feature of keratinocyte differentiation in hyperproliferative epidermis, vaginal epithelium, and buccal epithelium

2 June 2018

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2 June 2018

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Enhanced gap junction formation with LDL and apolipoprotein B*1

2 June 2018

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Expression of Cx26, Cx32 AND Cx43 gap junction proteins in normal and neoplastic human tissues

2 June 2018

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2 June 2018

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NorLeu3-A(1-7) stimulation of diabetic foot ulcer healing: results of a randomized, parallel-group, double-blind, placebo-controlled phase 2 clinical trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Connexins are mechanosensitive

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Connexins 26, 30, and 43: differences among spontaneous, chronic, and accelerated human wound healing

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Dynamic changes in connexin expression correlate with key events in the wound healing process

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Connexin43 mimetic peptide reduces vascular leak and retinal ganglion cell death following retinal ischaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Manipulating Cx43 expression triggers gene reprogramming events in dermal fibroblasts from oculodentodigital dysplasia patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

High glucose down-regulates intercellular communication in retinal endothelial cells by enhancing degradation of connexin 43 by a proteasome-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Inhibition of cytokine-induced connexin43 hemichannel activity in astrocytes is neuroprotective

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

TGF-beta3 inhibits chondrogenesis of cultured chick leg bud mesenchymal cells via downregulation of connexin 43 and integrin beta4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

LOW-RESISTANCE COUPLING BETWEEN GLAND CELLS. SOME OBSERVATIONS ON INTERCELLULAR CONTACT MEMBRANES AND INTERCELLULAR SPACE.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Connexins, pannexins and innexins: protein cousins with overlapping functions

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Altered connexin expression and wound healing in the epidermis of connexin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

High glucose induces alteration of gap junction permeability and phosphorylation of connexin-43 in cultured aortic smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

High glucose alters connexin 43 expression and gap junction intercellular communication activity in retinal pericytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Bioglass promotes wound healing by affecting gap junction connexin 43 mediated endothelial cell behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Acute downregulation of connexin43 at wound sites leads to a reduced inflammatory response, enhanced keratinocyte proliferation and wound fibroblast migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Hexamethylene bisacetamide protects peritoneal mesothelial cells from glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

A Connexin43 Mimetic Peptide Promotes Regenerative Healing and Improves Mechanical Properties in Skin and Heart

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Neuroprotection by both NMDA and non-NMDA receptor antagonists in in vitro ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Targeting connexin43 expression accelerates the rate of wound repair

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Downregulation of connexin 43 expression by high glucose reduces gap junction activity in microvascular endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

The connexin43 carboxyl-terminal peptide ACT1 modulates the biological response to silicone implants

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Connexin43 phosphorylation at S368 is acute during S and G2/M and in response to protein kinase C activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Molecular mechanisms controlling the fibrotic repair phenotype in cornea: implications for surgical outcomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Ischemia opens neuronal gap junction hemichannels

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Differential expression of connexins during stratification of human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00596

Inhibition of corneal fibrosis by topical application of blocking antibodies to TGF beta in the rabbit

21 January 2018

1 reference

12 December 2020

The junctions of normal human epidermis. A freeze-fracture study

1 reference

12 December 2020

Unique and shared functions of different connexins in mice

1 reference

12 December 2020

Accelerated wound closure in neutrophil-depleted mice

1 reference

12 December 2020

Gap26, a connexin mimetic peptide, inhibits currents carried by connexin43 hemichannels and gap junction channels

1 reference

12 December 2020

Diversity of gap junctional proteins: does it play a role in cardiac excitation?

1 reference

12 December 2020

Differential regulation of key stages in early corneal wound healing by TGF-beta isoforms and their inhibitors

1 reference

12 December 2020

In vitro corneal endothelial permeability in rabbit and human: the effects of age, cataract surgery and diabetes

1 reference

12 December 2020

Identifiers

DOI

10.3389/FPHYS.2016.00596

0 references

1 reference

PubMed publication ID

27999549

1 reference